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Inflated lambda values #51

@GabrielCabas

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@GabrielCabas

Hello, thank you very much for your work.

My question is regarding the GC Lambda values ​​that can be obtained from a tractor experiment. Is it normal for this value to be higher compared to a standard GWAS performed with Plink?

In particular my standard GWAS experiment achieves a lambda ~ 1.01. But separating by ancestry, I obtain ~1.18 in my target population.

Should I perform an extra step to correct this? or does TRACTOR prioritize other metrics?

Thanks for your time.

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