From 4778f790b97b19bce316f0c2f5a06242499e77a5 Mon Sep 17 00:00:00 2001 From: erinspace Date: Mon, 14 Sep 2015 18:11:26 -0400 Subject: [PATCH 1/3] Add openaire harvester, as OAI PMH for now In the future, we want to investigate many more sources for data as OpenAire has lots of rich APIs Using the OAI-PMH endpoint is a quick way to start using it as a data source right away. We can explore more routes of collaboration as we go forward. Addresses [#SHARE-14] and closes #274 --- scrapi/harvesters/openaire.py | 18 ++++++++++++++++++ 1 file changed, 18 insertions(+) create mode 100644 scrapi/harvesters/openaire.py diff --git a/scrapi/harvesters/openaire.py b/scrapi/harvesters/openaire.py new file mode 100644 index 00000000..f9e44a90 --- /dev/null +++ b/scrapi/harvesters/openaire.py @@ -0,0 +1,18 @@ +''' +Harvester for the OAI-PMH Publisher for OpenAIRE+. Powered by D-NET. for the SHARE project + +Example API call: http://api.openaire.eu/oai_pmh?verb=ListRecords&metadataPrefix=oai_dc +''' +from __future__ import unicode_literals + +from scrapi.base import OAIHarvester + + +class OpenaireHarvester(OAIHarvester): + short_name = 'openaire' + long_name = 'OAI-PMH Publisher for OpenAIRE+. Powered by D-NET.' + url = 'http://api.openaire.eu' + + base_url = 'http://api.openaire.eu/oai_pmh' + property_list = ['rights', 'source', 'relation', 'date', 'identifier', 'type', 'setSpec'] + timezone_granularity = True From 8fb630d5ac93e606425a67be4f1196631ba8be0a Mon Sep 17 00:00:00 2001 From: erinspace Date: Mon, 14 Sep 2015 18:14:06 -0400 Subject: [PATCH 2/3] Add openaire favicon --- img/favicons/openaire_favicon.ico | Bin 0 -> 32988 bytes 1 file changed, 0 insertions(+), 0 deletions(-) create mode 100644 img/favicons/openaire_favicon.ico diff --git a/img/favicons/openaire_favicon.ico b/img/favicons/openaire_favicon.ico new file mode 100644 index 0000000000000000000000000000000000000000..151eca1baaa93b204ded4693423dac971f11d08d GIT binary patch literal 32988 zcmeHv2Ut~Cx;ArX?!7a2(kC&ofz-42+WQc94&dw&hwlk4$Ee-%L!R-AqiL;p@iF|HZ_lz}v(` z;&=Ellh@g_*P9>B5@?pduP1>>C-KDkj^d>?Jq+dvy>z;bPLjH@mtw26ExlF4mI1Po z*hjKS9H48L($CN$r=Q{Pzh3XZ-<=Aboc_>d zI?2Hsd&wc2dyC~;`iZv_`-(+d`pQ$2`l-W{2g{vP21qS`zhD0IdtM^Me?{2qT19uT zvXAa44UKVBrmyQFzqhuVvMH{coDXQ-mU#b zc5;7Zed<8*&h~*~%Jw00-y|0+kL7%{)z^W^^W z$0>tEL&`u=kvvpNP8nwXdd4st*Q^n;8MN)`5BNypn1?wC({Ov6fsqc6wHHU%I4I{= zIY`%IyAU(+ZzTSW8h&E`G5p)_!k;x%#m-@r!7zn#5Z`3E$sg@-lgqPQM0D10;hybo z^}-)P0!vJs{t~Vzmf?D3QiPpIi?CO|Sl3BKTqix&bW+#^)^=fY6o~CA5Z7HGzJ~zU zKQ=lG&H(}HKXCqIYd?W){RNT-2y7oDkUCf(W2iv3tBRZvDze-JcDjl)8E#@jw!0X$ z!(Eta`t|pcLz0R6pMw>pZI~*L4l{_fNPGFhY6le>eyug(U-L8Zrx1TS@n^Xx*gafD z?no8cZsNucH*qFwgp#y#l$em|Zrl3z!vBty-3wuQ;U1y9cTlj3 z_*ZlMV>tf51b-TJK!&ykToq(f204_$Znj+`#KoPXlr1|)>IbE{+CKAp>)f2w|M%ung>hF%>Ejx*IO)=<@q5(u3v3uz}gPB;M&JZy$!;JIhz?G^cGm%LBiUu zTo2v#T>I1u)c^6+fg7m*Y5QRl_5Wt-|1EvF4^aPY8=!FQtJM2?qzu;f0~@6Dw?JzD zc1Ry&3GM^LZa}`L9=W5`%XuD3>27ziFxO48`K|D4Yd%;f#uI;5up)gOV{eN!9qmB< zhZT}JmbZHm%T51*Fzc3xwzs~6Keh?~zv(~XzgzzifASz=AIdgJMsi0Mdwyi68rIrq(w73 zY*j?ssR&c75n|Pb_*)>v{6&P@v_gbpiYVK5SY>aH7zYci>uim*;z+hzy^uVmTVT-+Kae*w_`I!Qm-~hc4~=~-mQ>6pdB(@bl5dYMX9eH%6)CI z$3w2q^_1u5k5w#>&$9aO$0>st2Z#T8Uy?>Fm*s*LigF{`)=}ex zJc}sl1;iLyVr~02Sl6KqVmr3M`p#{zp>tbo=+p`u9G*wK-P1<=+d2RDOdf=NOZ-u_ zbS}ykjYiIBN9-7EiOgYE)B_6j0QW^t@eSv|;XPi;n}y!07Rq^Sk6>Bu!xj-N#F+?H z<@^?SzilhL+wytD^yrMd*B9et-X5GgScQfiDacH)j+M5w~JFIuK z0{uUu{@c`xSFV9g-OaIu^FOJdg!JJZkUwh_4u&np=^dN!N#PD0-?j=BulZrOR|m?V z9d-_BN4v-dg`Ua}d7k3SJWqK;p1XCY#|EA^4w2=FA&Qc*T!@RIk`5u3=6L6&7qF~d zYi#p%M}1ZXZhZeew8uAJe2z0E1*l#ViITS$V|T!0q>pvQcK5zW^&Ws76I_w)KMFhj zT(HBpA2P@E$DWxUC|fcEHIZ-PL~1-ftt`QnvmfI7OJCrNV^ye&dmjZ;`XXaMTcr1S z0lS8^Lz%B09Cze-O1ld@bORozO~|o-l`=RGBFR^lTUlahn^wfn^{tnX6)*!I?kh85 zZ~F87SC?`5qYrWM*b$u0+l51M(WnS{6Z=BmKxNcY)T|9fRn&W^SiTrlE8jvxavaX? 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+++++++++++++++++++++++++++++++++++++++ 1 file changed, 3134 insertions(+) create mode 100644 tests/vcr/openaire.yaml diff --git a/tests/vcr/openaire.yaml b/tests/vcr/openaire.yaml new file mode 100644 index 00000000..f5ec91fa --- /dev/null +++ b/tests/vcr/openaire.yaml @@ -0,0 +1,3134 @@ +interactions: +- request: + body: null + headers: + Accept: ['*/*'] + Accept-Encoding: ['gzip, deflate'] + Connection: [keep-alive] + User-Agent: [python-requests/2.4.1 CPython/2.7.9 Darwin/13.4.0] + method: GET + uri: http://api.openaire.eu/oai_pmh?verb=ListRecords&metadataPrefix=oai_dc&from=2015-09-12T00:00:00Z&until=2015-09-14T00:00:00Z + response: + body: {string: "\n\n\n\t2015-09-14T22:30:38Z\n\thttp://api.openaire.eu/oai_pmh\n\n\t\n\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d9724fead4e24076eb906d34e7262a3d\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Anterior segment dysgenesis after + overexpression of transforming growth factor-\u03B2-induced gene, \u03B2igh3, + in the mouse eye\n\t\t\t\t 2007-10-16\n\t\t\t\t + \ Molecular Vision\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:749841\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmid/17982418\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC2185514\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Kim, + Jung-Eun\n\t\t\t\t Kim, Hong-Kyun\n\t\t\t\t + \ Kim, Eung Kweon\n\t\t\t\t Han, + Min-Su\n\t\t\t\t Bae, Yong-Chul\n\t\t\t\t + \ Kim, In-San\n\t\t\t\t Kim, Tae-Im\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC2185514\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::36d55c9c218aed3d4146ed2ad42b3274\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2194569\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::6f96b740738d7cf9b4050ecd653d4ec9\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8795384\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/3675291\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16710170\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8077289\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12963107\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12242711\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9799082\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12577311\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8921218\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10906123\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11867580\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/3079999\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/7738366\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10845607\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2177343\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/5867355\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/7862405\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9054935\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12882779\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10201945\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8425829\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/5469558\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/3678824\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9112985\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/3281888\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11784073\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15448476\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11127579\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::521798dc67f2e1fdd4bd7fcced825a69\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9217007\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8024701\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/1388724\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10723086\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::d93d3162166c20e9653c57808a2dd846\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9449696\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10424302\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/4824179\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9878215\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8942889\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8287980\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d5744f18c928bb975ef204dc7bc6b399\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Transcription, + Chromatin, and Epigenetics\n\t\t\t\t The Deubiquitinating + Enzyme BAP1 Regulates Cell Growth via Interaction with HCF-1*\n\t\t\t\t + \ 2009-10-08\n\t\t\t\t American Society + for Biochemistry and Molecular Biology\n\t\t\t\t eng\n\t\t\t\t + \ The deubiquitinating enzyme BRCA1-associated protein 1 + (BAP1) possesses growth inhibitory activity and functions as a tumor suppressor. + In this study we report that BAP1 also plays positive roles in cell proliferation. + BAP1 depletion by RNAi inhibits cell proliferation as does overexpression + of a dominant negative mutant of BAP1. Mass spectrometry analyses of copurified + proteins revealed that BAP1 is associated with factors involved in chromatin + modulation and transcriptional regulation. We show that the interaction with + host cell factor-1 (HCF-1), a cell-cycle regulator composed of HCF-1N and + HCF-1C, is critical for the BAP1-mediated growth regulation. We found that + HCF-1N is modified with Lys-48-linked polyubiquitin chains on its Kelch domain. + The HCF-1 binding motif of BAP1 is required for interaction with HCF-1N and + mediates deubiquitination of HCF-1N by BAP1. The importance of the BAP1-HCF-1 + interaction is underscored by the fact that growth suppression by the dominant + negative BAP1 mutant is entirely dependent on the HCF-1 binding motif. These + results suggest that BAP1 regulates cell proliferation by deubiquitinating + HCF-1.\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC2797188\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2025082\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Machida, + Yuka\n\t\t\t\t Wohlschlegel, James A\n\t\t\t\t + \ Vashisht, Ajay A.\n\t\t\t\t Machida, + Yuichi J.\n\t\t\t\t Dutta, Anindya\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC2797188\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d63f15c62a5ee8ea3079a49a3759b8cd\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Presence of vancomycin-resistant + enterococci in farm and pet animals.\n\t\t\t\t 1996-10-01\n\t\t\t\t + \ eng\n\t\t\t\t Enterococcus + faecium strains with vanA-mediated glycopeptide resistance were isolated by + enrichment culture from the intestines and feces of several animal species, + mainly horses and dogs (8% positive), chickens (7% positive), and pigs (6% + positive). Other vanA-positive enterococcal strains were identified as E. + durans in gallinaceous birds, E. faecalis in a horse, and E. gallinarum in + a pheasant. Samples from pigeons, cage birds, and ruminants were negative. + It was concluded that vancomycin resistance is widespread among isolates from + farm and pet animals.\n\t\t\t\t Europe PubMed + Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC163520\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:209901\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Devriese, + L A\n\t\t\t\t Haesebrouck, F\n\t\t\t\t + \ Goossens, H\n\t\t\t\t Vandamme, + P.\n\t\t\t\t Pot, B.\n\t\t\t\t Hommez, + J\n\t\t\t\t Ieven, M.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC163520\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d37aac895de4276422f6b52bbd7e775e\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Case + Reports\n\t\t\t\t Removal of Retained Lead Shot + Through Laparoscopic Appendectomy\n\t\t\t\t 2003-01-01\n\t\t\t\t + \ Society of Laparoendoscopic Surgeons\n\t\t\t\t + \ eng\n\t\t\t\t We describe + a patient presenting with lead shot in his appendix. A plain radiograph of + his lumbar spine was performed for back pain, and an incidental finding of + lead shot retained within the appendix was seen. Lead shot in the appendix + is associated with appendicitis, and 2 cases have been reported of lead intoxication. + We suggest that an elective laparoscopic appendectomy should be offered to + patients as a possible management option.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2053221\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmid/12856854\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC3015486\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Sian, + P. S.\n\t\t\t\t Lloyd, D. M., Coates, A., Knopp, + J., Oram, S., & Rowbotham, S.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3015486\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/5538761\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9892790\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/5229946\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/7877052\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d85417b40813888d1827931888f9a962\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Discrimination among pheromone + component blends by interneurons in male antennal lobes of two populations + of the turnip moth, Agrotis segetum.\n\t\t\t\t 1996-07-23\n\t\t\t\t + \ eng\n\t\t\t\t A difference + in female pheromone production and male behavioral response has previously + been found in two populations of the turnip moth, Agrotis segetum, originating + from Sweden and Zimbabwe, respectively. In this study, we investigated the + pheromone response of antennal lobe interneurons of males of the two populations + by intracellular recordings, stimulating with single pheromone components + and various inter- and intra-populational pheromone blends. Three major physiological + types of antennal lobe neurons were established in the two populations according + to their responses to different stimuli. One type responded broadly to almost + all the stimuli tested. The second type responded selectively to some of the + single components and blends. The third type did not respond to any single + components but did respond to certain blends. Furthermore, some neurons of + the second and third type recognized strain specific differences in ratios + between pheromone components. Both projection neurons and local interneurons + were found among these three types. Two pheromone responding bilateral projection + neurons are reported for the first time in this paper.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC38868\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:71649\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Anton, + S.\n\t\t\t\t Hansson, B S\n\t\t\t\t + \ Wu, W.\n\t\t\t\t L\xF6fstedt, + C\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC38868\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d9f970294f7157f3e1d47545dea10198\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ The Role of Childhood Traumatic Experience in Personality Disorders + in China\n\t\t\t\t 2011-12-14\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC4159500\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:3130547\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Zhang, + Tianhong\n\t\t\t\t Dai, Yunfei\n\t\t\t\t + \ Wang, Lanlan\n\t\t\t\t Chow, Annabelle\n\t\t\t\t + \ Xiao, ZePing\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC4159500\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d41b79800d4deff8711b54eebe7368c8\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Editorials\n\t\t\t\t + \ Cheaper antiretrovirals to treat AIDS in South Africa : They + are at their most cost effective in preventing mother to child transmission\n\t\t\t\t + \ 2000-06-10\n\t\t\t\t British Medical + Journal\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC1127350\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:246925\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Schneider, + Helen\n\t\t\t\t Zwi, Karen\n\t\t\t\t + \ S\xF6derlund, Neil\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1127350\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::db4bfbdc2ddb580362dd33261d5b7def\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Intra-myocardial Delivery of Mesenchymal Stem Cells Ameliorates + Left Ventricular and Cardiomyocyte Contractile Dysfunction Following Myocardial + Infarction\n\t\t\t\t 2010-03-18\n\t\t\t\t + \ eng\n\t\t\t\t Although mesenchymal + stem cells (MSC) transplantation may improve the overall heart function, the + heterogeneity of myocardial cells makes it difficult to determine the nature + of cells benefited from transplantation. This study evaluated the effect of + intra-myocardial MSC transplantation on myocardial function following MI. + Enhanced green fluorescent protein (EGFP)-expressing donor MSCs from C57BL/6-Tg + (UBC-GFP) 30Scha/J mice were transplanted into LV free wall in the region + bordering an infarct in C57 recipient mice following ligation of left main + coronary artery (MI+MSC group). Ten days after MI, LV function was assessed + using echocardiography. Cardiomyocyte contractility and intracellular Ca2+ + transients were measured in cells from the area at risk surrounding the infarct + scar. The EGFP donor cells were traced in the MSC recipient mice using fluorescence + microscopy. TUNEL, H&E and Masson trichrome staining were used to assess + apoptosis, angiogenesis and myocardial fibrosis, respectively. MI dilated + LV as evidenced by increased end-diastolic and systolic diameters. MI significantly + reduced fractional shortening, cardiomyocyte peak shortening, and maximal + velocity of shortening and relengthening, all of which were attenuated or + abrogated by MSC therapy. MI also reduced resting intracellular Ca2+, intracellular + Ca2+ rise and decay rate, which were reconciled by MSC. MSC therapy attenuated + MI-induced apoptosis and decreased angiogenesis but not myocardial fibrosis + in peri-infarct area. Taken together, our results demonstrated that MSC therapy + significantly improved both LV and cardiomyocyte function possibly associated + with its beneficial role in apoptosis and angiogenesis, indicating a key role + for cardiomyocytes in stem cell tissue engineering.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2862825\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2113660\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Li, + Qun\n\t\t\t\t Turdi, Subat\n\t\t\t\t + \ Thomas, D Paul\n\t\t\t\t Ren, + Jun\n\t\t\t\t Zhou, Tianjie\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC2862825\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d985f98c13ca4ebf12b41a96abd1e5a4\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Survival.\n\t\t\t\t + \ 1971-02-01\n\t\t\t\t Royal College + of General Practicioners\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2156301\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:648762\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Miles, + S.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2156301\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da50b8c53cbc058ee077f41fe18fc02a\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Clinical + Research\n\t\t\t\t Effect of cardiac resynchronization + therapy in patients without left intraventricular dyssynchrony\n\t\t\t\t + \ 2012-01-24\n\t\t\t\t Oxford University + Press\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3345550\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2611212\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Witkowski, + Tomasz G.\n\t\t\t\t Bleeker, Gabe B\n\t\t\t\t + \ Ng, Arnold C. T.\n\t\t\t\t van + Erven, Lieselot\n\t\t\t\t Ewe, See H.\n\t\t\t\t + \ Delgado, Victoria\n\t\t\t\t Bax, + Jeroen J.\n\t\t\t\t Auger, Dominique\n\t\t\t\t + \ van Bommel, Rutger J.\n\t\t\t\t Martin + J. Schalij\n\t\t\t\t Bertini, Matteo\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC3345550\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d974c8f655184d9ef1a03b7964e654a5\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Poster + Presentation\n\t\t\t\t Trend in outcome of critically + ill patients with co-morbidity: a 15-year study\n\t\t\t\t 2010-01-01\n\t\t\t\t + \ BioMed Central\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2934109\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.1186/cc8658\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1962462\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Keegan, + MT\n\t\t\t\t Gajic, O\n\t\t\t\t Afessa, + B\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2934109\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d995a5fbbabc07aad80b708bb462e0d9\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Articles\n\t\t\t\t + \ STUDIES ON CHEYNE-STOKES RESPIRATION\n\t\t\t\t 1932-11-01\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC435882\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:762083\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Steele, + J. Murray\n\t\t\t\t Anthony, Albert J.\n\t\t\t\t + \ Cohn, Alfred E.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC435882\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d58550704a56183ff3942548c6116a2b\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Domain communication in the dynamical + structure of human immunodeficiency virus 1 protease.\n\t\t\t\t + \ 1990-11-01\n\t\t\t\t eng\n\t\t\t\t + \ A dynamical model for the structure of the human immunodeficiency + virus 1 (HIV-1) protease dimer in aqueous solution has been developed on the + basis of molecular dynamics simulation. The model provides an accurate account + of the crystal geometry and also a prediction of the structural reorganization + expected to occur in the protein in aqueous solution compared to the crystalline + environment. Analysis of the results by means of dynamical cross-correlation + coefficients for atomic displacements indicates that domain-domain communication + is present in the protein in the form of a molecular \"cantilever\" and is + likely to be involved in enzyme function at the molecular level. The dynamical + structure also suggests information that may ultimately be useful in understanding + and further development of specific inhibitors of HIV-1 protease.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC55060\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1244115\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Rosenberg, + I E\n\t\t\t\t Swaminathan, S.\n\t\t\t\t + \ Harte, W E\n\t\t\t\t Mansuri, + M M\n\t\t\t\t Martin, J C\n\t\t\t\t + \ Beveridge, D.L.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC55060\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d589319ffaa44dbc04be9876e36d0802\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Article\n\t\t\t\t + \ Medicare Beneficiary Knowledge of the Part D Program and Its + Relationship with Voluntary Enrollment\n\t\t\t\t 2012-12-12\n\t\t\t\t + \ Centers for Medicare & Medicaid Services\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC4006476\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2989305\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Wolff, + Jennifer\n\t\t\t\t Howell, Benjamin Lee\n\t\t\t\t + \ Herring, Bradley\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC4006476\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d5936876102cd0a5b666424c1f97541a\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Articles\n\t\t\t\t + \ Anatomic Pathway of Bile Formation\n\t\t\t\t 1960-09-01\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC1942313\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1537544\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Sanders, + E\n\t\t\t\t Ashworth, C.T.\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC1942313\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d59f1effa7aa05979a732d8368dfd1a7\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Editorials\n\t\t\t\t + \ Holding relationships in general practice: What are they? How + do they work? Are they worth having?\n\t\t\t\t 2011-08-01\n\t\t\t\t + \ Royal College of General Practitioners\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC3145501\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2412437\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t George + K. Freeman\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3145501\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d6510444cb0f4578ec8f7949edd4d0e1\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ RNA Binding by the Brome Mosaic Virus Capsid Protein and the + Regulation of Viral RNA Accumulation\n\t\t\t\t 2009-05-27\n\t\t\t\t + \ eng\n\t\t\t\t Viral capsid + proteins (CPs) can regulate gene expression and encapsulate viral RNAs. Low-level + expression of the brome mosaic virus (BMV) CP was found to stimulate viral + RNA accumulation, while higher levels inhibited translation and BMV RNA replication. + Regulation of translation acts through an RNA element named the B box, which + is also critical for the replicase assembly. The BMV CP has also been shown + to preferentially bind to an RNA element named SLC that contains the core + promoter for genomic minus-strand RNA synthesis. To further elucidate CP interaction + with RNA, Available online we used a reversible cross-linking\u2013peptide + fingerprinting assay to identify 27 May 2009 peptides in the capsid that contact + the SLC, the B-box RNA, and the encapsidated RNA. Transient expression of + three mutations made in residues within or close by the cross-linked peptides + partially released the normal inhibition of viral RNA accumulation in agroinfiltrated + Nicotiana benthamiana. Interestingly, two of the mutants, R142A and D148A, + were found to retain the ability to down-regulate reporter RNA translation. + These two mutants formed viral particles in inoculated leaves, but only R142Awas + able to move systemically in the inoculated plant. The R142A CP was found + to have higher affinities for SLC and the B box compared with those of wild-type + CP and to alter contacts to the RNA in the virion. These results better define + how the BMV CP can interact with RNA and regulate different viral processes.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2774812\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1668857\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Vaughan, + Robert C.\n\t\t\t\t Kao, C. Cheng\n\t\t\t\t + \ Yarbrough, Ian\n\t\t\t\t Yi, Guanghui\n\t\t\t\t + \ Dharmaiah, S.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2774812\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d656d13f0fa73340df102ff99f09a0cf\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ KATP channel blocker does not abolish the protective effect + of NHE1 inhibition against ischaemia/reperfusion in aged myocardium\n\t\t\t\t + \ 2010-08-01\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2900462\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2151389\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Liu, + Hong\n\t\t\t\t Moore, Peter G.\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC2900462\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d6576011e3c94fae6eeda62291375188\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Abstracts\n\t\t\t\t + \ Medical genetics: advances in brief: Factor V Leiden mutation: + an unrecognised cause of hemiplegic cerebral palsy, neonatal stroke and placental + thrombosis\n\t\t\t\t 1998-02-01\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC1051231\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:789006\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Reid, + Evan\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1051231\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d65cb116f90b88f86d27b073eedb7e8c\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Obituary\n\t\t\t\t + \ FREDERICK WILLCOCKS, M.D., F.R.C.P\n\t\t\t\t 1908-02-08\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC2435915\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1054379\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2435915\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d37b20b9f5529d7519326e281b3e4aae\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Scientific + and General\n\t\t\t\t Symposium on Civilian Wartime + Problems in Nutrition: From the Standpoint of the Physician: What Constitutes + a Normal Diet*\n\t\t\t\t 1944-12-01\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC1780873\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1428636\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Hardgrove, + Grace G.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1780873\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d37b80b5cd4ea94117af6dbbee86fb96\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t News + Roundup\n\t\t\t\t Woman who had attended euthanasia + workshop kills herself\n\t\t\t\t 2002-12-07\n\t\t\t\t + \ BMJ\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC1169957\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:290050\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Zinn, + Christopher\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1169957\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d37ce5829aa5beb30831a53339f0086c\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Targeting Trauma-related Interventions and Improving Outcomes + for Women with Co-occurring Disorders\n\t\t\t\t 2007-11-13\n\t\t\t\t + \ eng\n\t\t\t\t National attention + to the effects of interpersonal trauma has led mental health systems to adopt + policies on trauma-related services; however, there is a lack of clarity regarding + targeting of these services. Data from the Women, Co-occurring Disorders and + Violence Study (WCDVS) were reanalyzed by grouping women on their baseline + PTSD and substance abuse presentation and assessing the differential response + to an integrated mental health/substance abuse intervention. Treatment effects + were largest for subgroups characterized by high levels of PTSD, whereas the + effects for those in the low symptom group were near zero. These findings + underscore the need for clinicians to conduct careful assessments of trauma-related + symptoms and to target the most intensive trauma-related interventions to + individuals with PTSD symptoms.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2743153\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1877621\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Ellis, + Alan R\n\t\t\t\t Morrissey, Joseph P.\n\t\t\t\t + \ Cusack, Karen J.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2743153\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d3bc190bfe3cb9a135eafe44bf98c10f\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t E. + Pediatrics and Lung Development\n\t\t\t\t Transcriptomic + Analysis of Human Lung Development\n\t\t\t\t 2009-10-08\n\t\t\t\t + \ American Thoracic Society\n\t\t\t\t eng\n\t\t\t\t + \ Rationale: Current understanding of the molecular regulation + of lung development is limited and derives mostly from animal studies.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2797628\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1898414\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Bhattacharya, + Soumyaroop\n\t\t\t\t Kho, Alvin T\n\t\t\t\t + \ Kohane, Isaac S\n\t\t\t\t Leeder, + J Steven\n\t\t\t\t Carey, Vincent J\n\t\t\t\t + \ Tantisira, Kelan G\n\t\t\t\t Weiss, + Scott T.\n\t\t\t\t Gaedigk, Roger\n\t\t\t\t + \ Mariani, Thomas J.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2797628\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d8584fb8a0f06c2c69fb0235d451947d\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Echoes\n\t\t\t\t + \ Real time PCR diagnosis of genital herpes in routine practice\n\t\t\t\t + \ 2004-12-01\n\t\t\t\t BMJ Group\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC1770520\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:633574\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1770520\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d862131ba5bd724fbfaf3b50d710f136\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Functional and structural characterization of chimeras of a + bacterial genotoxin and human type I deoxyribonuclease\n\t\t\t\t + \ 2008-12-11\n\t\t\t\t eng\n\t\t\t\t + \ Chimeras composed of the cdtB gene of a novel bacterial + genotoxin and the human type I deoxyribonuclease (DNase I) gene were constructed + and their products characterized relative to the biochemical and enzymatic + properties of the native proteins. The product of a cdtB/DNase I chimera formed + a heterotrimer with the CdtA and CdtC subunits of the genotoxin and targeted + mutations increased the specific activity of the hybrid protein. Expression + of active chimeric gene products established that the CdtB protein is an atypical + divalent cation-dependent endonuclease and demonstrated the potential for + genetically engineering a new class of therapeutic agent for inhibiting the + proliferation of cancer cells.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3523320\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2522554\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Bandelac, + Georges\n\t\t\t\t Volgina, Alla\n\t\t\t\t + \ Cao, Linsen\n\t\t\t\t Dirienzo, + Joseph M.\n\t\t\t\t Korostoff, Jonathan\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC3523320\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d892a182aad274a355c958fa5f59ce68\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Antioxidant effects of green tea\n\t\t\t\t 2011-05-02\n\t\t\t\t + \ eng\n\t\t\t\t Consumption + of green tea (Camellia sinensis) may provide protection against chronic diseases, + including cancer. Green tea polyphenols are believed to be responsible for + this cancer preventive effect, and the antioxidant activity of the green tea + polyphenols has been implicated as a potential mechanism. This hypothesis + has been difficult to study in vivo due to metabolism of these compounds and + poor understanding of the redox environment in vivo. Green tea polyphenols + can be direct antioxidants by scavenging reactive oxygen species or chelating + transition metals as has been demonstrated in vitro. Alternatively, they may + act indirectly by up-regulating phase II antioxidant enzymes. Evidence of + this latter effect has been observed in vivo, yet more work is required to + determine under which conditions these mechanisms occur. Green tea polyphenols + can also be potent pro-oxidants, both in vitro and in vivo, leading to the + formation of hydrogen peroxide, the hydroxyl radical, and superoxide anion. + The potential role of these pro-oxidant effects in the cancer preventive activity + of green tea is not well understood. The evidence for not only the antioxidant, + but also pro-oxidant, properties of green tea are discussed in the present + review.\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC3679539\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2676653\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Forester, + Sarah C.\n\t\t\t\t Lambert, Joshua D\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC3679539\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d8a3856a40477fe40b1e8c6e66a6f0be\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Prieurianin Causes Weight Loss in Diet-Induced Obese Mice and + Inhibits Adipogenesis in Cultured Preadipocytes\n\t\t\t\t 2010-09-29\n\t\t\t\t + \ eng\n\t\t\t\t The global + increase in the incidence of obesity has emerged as one of the most serious + public health risks in recent years. Despite the enormity of the obesity pandemic, + there are currently only two FDA-approved therapies for its treatment and + these drugs exhibit modest efficacy and have limiting side effects. Prieurianin + is a plant limonoid product that deters feeding in insect larvae. We investigated + in this study the effects of prieurianin on weight loss and adipogenesis. + Our results showed that prieurianin causes weight loss by reducing energy + intake in obese mice on high-calorie diet. We also found that prieurianin + is anti-adipogenic in cultured preadipocytes and adipocytes by inhibiting + proliferation and differentiation of preadipocytes into adipocytes, and induces + either dedifferentiation or delipidation of mature adipocytes. Whether prieurianin + can potentially be used for obesity treatment in human warrants further investigation.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3093537\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2102971\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Kablan, + Ahmed\n\t\t\t\t Bosio, Raul M.\n\t\t\t\t + \ Chin, Khew-Voon\n\t\t\t\t Chin, + Andrew J.B.\n\t\t\t\t Saunders, Rudel A.\n\t\t\t\t + \ Shapiro, Joseph\n\t\t\t\t Szkudlarek-Mikho, + Maria\n\t\t\t\t Fujii, Kazuyuki\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC3093537\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da00cc2d674ee2b0e5bb78195518bec3\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Editor's + Spotlight/Take 5\n\t\t\t\t Editor\u2019s Spotlight/Take + 5: Orthopaedic Surgeons Frequently Underestimate the Cost of Orthopaedic Implants + (DOI 10.1007/s11999-012-2757-x)\n\t\t\t\t 2013-04-02\n\t\t\t\t + \ Springer-Verlag\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3706660\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:3014937\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Leopold, + Seth. S.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3706660\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da047405cd60cec80efa397c70127658\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Evidence for regulation of 3-hydroxy-3-methylglutaryl + coenzyme A reductase activity and cholesterol synthesis in nonhepatic tissues + of rat.\n\t\t\t\t 1976-08-01\n\t\t\t\t eng\n\t\t\t\t + \ The adenine analogue 4-aminopyrazolopyrimidine has been + reported previously to reduce the hepatic secretion of plasma lipoproteins + in rats, thereby lowering the plasma cholesterol level. In the current studies, + reduction of the plasma cholesterol level by 90% in rats through the administration + of aminopyrazolopyrimidine was found to be associated with a 5- to 30-fold + increase in the activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase + [mevalonate:NADP+ oxidoreductase (CoA-acylating), EC1.1.1.34] in kidney and + lung. In both tissues, the enhanced activity of this microsomal enzyme was + associated with a 3-fold elevation in the rate of cholesterol synthesis from + either [14C]acetate or [14C]octanoate. Comparable increases were not observed + in the activities of several other microsomal enzymes or in the rates of [14C]acetate + incorporation into saponifiable lipids or CO2. When administration of 4-aminopyrazolopyrimidine + was terminated, plasma cholesterol levels rose and 3-hydroxy-3-methylglutaryl-coenzyme + A reductase activity declined in the kidney in a reciprocal manner. These + data are consistent with the hypothesis that the low levels of 3-hydroxy-3-methylglutaryl-coenzyme + A reductase activity and cholesterol synthesis that are normally observed + in certain nonhepatic tissues of the rat are due to an active form of feedback + regulation mediated by cholesterol carried in plasma lipoproteins.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC430688\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:65584\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Goldstein, + J L\n\t\t\t\t Balasubramaniam, S\n\t\t\t\t + \ Faust, J R\n\t\t\t\t Brown, M. + S.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC430688\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da050547f33731516f396a195b4fdd64\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Inhibition of endothelium-dependent + vasorelaxation by arginine analogues: a pharmacological analysis of agonist + and tissue dependence.\n\t\t\t\t 1992-03-01\n\t\t\t\t + \ eng\n\t\t\t\t 1. Isolated + rings of rabbit external jugular vein (RbJV) and rat thoracic aorta (RA) were + used to study the effect of the NO synthase inhibitor L-NG-nitroarginine methyl + ester (L-NAME) on muscarinic and 5-hydroxytryptamine (5-HT) receptor-stimulated, + endothelium-dependent vascular relaxations. 2. In RbJV relaxations produced + by the endothelial 5-HT receptor agonist alpha-methyl-5-HT were potently and + non-surmountably inhibited by L-NAME (10 microM), whereas acetylcholine relaxations + in this tissue were unaffected by this concentration of inhibitor. By contrast, + acetylcholine relaxations in RA were virtually abolished by 10 microM L-NAME. + In each case an equivalent concentration of D-NAME was without effect on agonist-induced + relaxations. 3. The different effect of L-NAME on acetylcholine relaxations + in RbJV and RA was not due to muscarinic receptor differences. Affinity estimates + for acetylcholine (pKA = 6.12 +/- 0.09; 6.09 +/- 0.08 respectively) and for + 4-diphenyl-acetoxy-N-methylpiperidine methobromide (4-DAMP, pKB = 9.01 +2- + 0.012; 9.24 +/- 0.16 respectively) indicated that the receptors in both tissues + belong to the same M3 class. Tissue differences resulting from the release + of a cyclo-oxygenase product or a glibenclamide-sensitive K(+)-channel-linked + hyperpolarizing factor were also ruled out by selective inhibition of these + pathways. 4. When phenoxybenzamine was used to reduce the efficacy of acetylcholine + in RbJV so that it behaved as a partial agonist in this tissue, L-NAME (10 + microM) now produced non-surmountable inhibition of relaxation responses. + In untreated tissues the same concentration of L-NAME also profoundly inhibited + responses produced by butyrylcholine and pilocarpine, both of which behave + as partial agonists at the M3 receptor in RbJV. 5. A simple model was developed + which describes the theoretical behaviour of receptor-stimulated synthesis + and release of NO. The model predicts that competitive inhibition of NO formation + results in parallel displacements of the agonist response curve in the case + of high efficacy agonist, but right-shift with concomitant depression of the + curve maximum in the case of low efficacy agonists. Simulations based on the + model showed reasonable agreement with the experimental data. 6. It is concluded + that analogues of L-arginine demonstrate tissue- and agonist-dependence in + terms of their ability to inhibit receptor-mediated events involving the liberation + of NO. This behaviour can reflect differences in agonist efficacy in the receptor + systems being studied, a possibility that should be ruled out before apparent + resistance to inhibition is taken as evidence for the involvement of heterogeneous + endothelium-derived relaxing factors (EDRFs).\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC1908470\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:663456\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Giles, + H\n\t\t\t\t Martin, G. R.\n\t\t\t\t + \ Bolofo, M. L.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1908470\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d42989edb5b89763c8566e33487233d3\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Physical + Sciences: Astronomy\n\t\t\t\t Unstable spiral modes + in disk-shaped galaxies: Enhancement of growth rate*\n\t\t\t\t + \ 1976-11-01\n\t\t\t\t eng\n\t\t\t\t + \ An additional effect not considered in our earlier papers + is found to enhance the rate of growth of spiral modes in disk-shaped galaxies. + This enhanced growth appears to be attributable to the combined influence + of differential rotation and tangential forces. For certain galaxy models, + rapid temporal growths are possible (comparable to those found in numerical + experiments), but in many real galaxies, these tendencies to extreme growth + rates are probably reduced to lower levels by competing effects such as wave + absorption at inner Lindblad resonance.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC431208\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:760622\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Mark, + James W.-K.\n\t\t\t\t Lau, Y. Y.\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC431208\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d43521916c74762826b49c024d3e5dfe\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Clinical + Medicine\n\t\t\t\t Standardized Treatment of Severe + Methanol Poisoning With Ethanol and Hemodialysis\n\t\t\t\t 1985-03-01\n\t\t\t\t + \ eng\n\t\t\t\t Seven patients + with methanol poisoning were treated with ethanol, hemodialysis and supportive + measures. The interval between ingestion and initiation of ethanol therapy + varied from 3 to 67 hours and from ingestion to dialysis from 9 to 93 hours. + All patients survived, but one had permanent visual impairment. A 10% ethanol + solution administered intravenously is a safe and effective antidote for severe + methanol poisoning. Ethanol therapy is recommended when plasma methanol concentrations + are higher than 20 mg per dl, when ingested doses are greater than 30 ml and + when there is evidence of acidosis or visual abnormalities in cases of suspected + methanol poisoning.\n\t\t\t\t Europe PubMed + Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC1306022\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1131729\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Ekins, + Brent R.\n\t\t\t\t Rollins, Douglas E.\n\t\t\t\t + \ Gregory, Martin C.\n\t\t\t\t Duffy, + Douglas P.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1306022\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::db5205f0d9246c5dc9320ad09142c5e9\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Original + Article\n\t\t\t\t Growth Inhibition and Apoptosis + with H31 Metabolites from Marine Bacillus SW31 in Head and Neck Cancer Cells\n\t\t\t\t + \ 2010-12-01\n\t\t\t\t Korean Society + of Otorhinolaryngology-Head and Neck Surgery\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/doi/10.3342/ceo.2010.3.4.217\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmid/21217964\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1999054\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC3010542\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Kim, + Jang Hee\n\t\t\t\t Choi, Eun Chang\n\t\t\t\t + \ Kang, Sung Un\n\t\t\t\t Kwon, + Hak Cheol\n\t\t\t\t Pyun, Jung Hee\n\t\t\t\t + \ Lee, Ha Neul\n\t\t\t\t Lee, Mi + Hye\n\t\t\t\t HWANG, Hye Sook\n\t\t\t\t + \ Lim, Young Chang\n\t\t\t\t Cho, + Ki Woong\n\t\t\t\t Kim, Chul-Ho\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC3010542\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18045195\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18486742\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16406520\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9097412\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17268607\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15510160\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/14767508\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10213228\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/14645636\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11295816\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10412949\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::a8ce1a5cddd5cc3e27acacc12b626374\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12543647\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18287387\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18005350\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12678733\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/7463489\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17045795\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______261::43136b08a7340e473bac5df6ee78d40d\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10403638\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18931972\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9006499\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8863440\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9190289\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______970::01e297d4513824c8854eb390dcb5fa93\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19072995\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16763277\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12833244\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18493941\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/7984417\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9218414\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:dedup_wf_001::4a8840994412a4c4c25d74ecbbcf4d9d\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18950535\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16307377\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::db901522d13ef3a34063b74231c8b7ff\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Three-dimensional visualization of nanostructured surfaces and + bacterial attachment using Autodesk\xAE Maya\xAE\n\t\t\t\t 2014-02-28\n\t\t\t\t + \ Nature Publishing Group\n\t\t\t\t eng\n\t\t\t\t + \ There has been a growing interest in understanding the + ways in which bacteria interact with nano-structured surfaces. As a result, + there is a need for innovative approaches to enable researchers to visualize + the biological processes taking place, despite the fact that it is not possible + to directly observe these processes. We present a novel approach for the three-dimensional + visualization of bacterial interactions with nano-structured surfaces using + the software package Autodesk Maya. Our approach comprises a semi-automated + stage, where actual surface topographic parameters, obtained using an atomic + force microscope, are imported into Maya via a custom Python script, followed + by a \u2018creative stage', where the bacterial cells and their interactions + with the surfaces are visualized using available experimental data. The \u2018Dynamics' + and \u2018nDynamics' capabilities of the Maya software allowed the construction + and visualization of plausible interaction scenarios. This capability provides + a practical aid to knowledge discovery, assists in the dissemination of research + results, and provides an opportunity for an improved public understanding. + We validated our approach by graphically depicting the interactions between + the two bacteria being used for modeling purposes, Staphylococcus aureus and + Pseudomonas aeruginosa, with different titanium substrate surfaces that are + routinely used in the production of biomedical devices.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/doi/10.1038/srep04228\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2926580\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmid/24577105\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC3937790\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Elena + P Ivanova\n\t\t\t\t Boshkovikj, Veselin\n\t\t\t\t + \ Fluke, Christopher J\n\t\t\t\t Crawford, + Russell J.\n\t\t\t\t info:eu-repo/semantics/dataset/openaire/oai:dnet:datacite____::da75fe21c5530dc5709166348bf11f55\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC3937790\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10033323\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21979427\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19399426\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22546051\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21288031\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19291757\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19631553\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22355680\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19842625\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22674670\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22719236\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22432024\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18698626\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19280970\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17608555\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22686938\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21728964\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21663769\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17900745\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d98e1b6d58974e64334e81a762575275\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Instructional + Courses/Symposia\n\t\t\t\t Activity-based Therapies + in Spinal Cord Injury:: Clinical Focus and Empirical Evidence in Three Independent + Programs\n\t\t\t\t 2012-01-01\n\t\t\t\t Thomas + Land Publishers, Inc.\n\t\t\t\t eng\n\t\t\t\t + \ This article summarizes presentations of a symposium examining + the potential impact of activity-based therapies (ABT) in promoting neurological + and functional recovery after spinal cord injury (SCI). The symposium addressed + 3 key questions concerning activity-based therapy in SCI: (1) What clinical + approaches are used? (2) Is there empirical evidence supporting efficacy of + ABT in promoting neurological recovery and improving overall function, health, + and quality of life? (3) What are the issues related to long-term viability + of ABT?\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC3584743\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2587933\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Tefertiller, + Candy\n\t\t\t\t Larson, Cathy A.\n\t\t\t\t + \ Michael L. Jones\n\t\t\t\t Harness, + Eric\n\t\t\t\t Denison, Paula\n\t\t\t\t + \ Evans, Nicholas\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3584743\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da59e4cbe9894a3b273b60b3ff99eb65\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Hospital infections in Spain. + I. Staphylococcus aureus (1978-91).\n\t\t\t\t 1993-06-01\n\t\t\t\t + \ Cambridge University Press\n\t\t\t\t eng\n\t\t\t\t + \ This study was undertaken to determine the distribution + of phage types of Staphylococcus aureus isolates from hospital outbreaks or + sporadic cases received in our laboratory during the past 14 years. The records + for 15,803 isolates from 55 Spanish hospitals have been analysed. In relation + to sporadic isolates we have been able to detect the predominance of phage + group I and non-typable staphylococcal strains. Since 1989, we have observed + a considerable increase in hospital infection caused by methicillin-resistant + S. aureus strains which we could differentiate in to two groups; one belonging + to phage group III (6/47/54/75/77/84/85) and other groups of nontypable strains + which could be classified as phage group I-III after heat treatment (29/77/84) + and with similar patterns by reverse typing (6/47/53/54/75/83A/84/85/W57/1030/18042). + During 1990 and 1991, these strains have extended widely to at least six different + autonomous regions creating an epidemic situation in Spain.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2272293\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1603726\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t J.A. + S\xE1ez Nieto\n\t\t\t\t G\xF3mez, E\n\t\t\t\t + \ Mart\xEDn Bourgon, C.\n\t\t\t\t Trincado, + P.\n\t\t\t\t Mart\xEDn de Nicol\xE1s, M. M.\n\t\t\t\t + \ Vindel, A.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2272293\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da5b136267a37faea28d0c29bef46fde\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Role of flagella in adhesion of + Pseudomonas fluorescens to tendon slices.\n\t\t\t\t 1991-06-01\n\t\t\t\t + \ eng\n\t\t\t\t Tendon slices + were used as model surfaces to investigate the role of flagella in the adhesion + of Pseudomonas fluorescens to meat. The slices were introduced into a specially + designed flow chamber, which was then filled with a suspension of the organism, + and the tendon surface was observed at a x640 magnification. The same events + that occur during the colonization of glass surfaces (apical adhesion of cells + with rotation around the contact point, longitudinal adhesion, detachment + of apically and longitudinally adherent cells) were also observed on tendon. + Mechanical removal of the flagella resulted in no change in the contact angles + with 0.1 M saline or alpha-bromonaphthalene, in the electrophoretic mobility, + or in the adhesion of the organism to hydrophobic and ion-exchange resins. + In addition, cells from which flagella had been mechanically removed still + adhered extensively to tendon. Nevertheless, under comparable conditions (bacterial + concentration, contact time), flagellated cells adhered to tendon in larger + numbers than did deflagellated cells. This was entirely due to the ability + of the motile flagellated cells to reach tendon in greater numbers than deflagellated + cells.\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC183444\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:10546\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Idziak, + E S\n\t\t\t\t Piette, J P\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC183444\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da64ffb33dee53612879f3c35dad4e78\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Hyperoxaluria and recurrent stone + formation apparently cured by short courses of pyridoxine.\n\t\t\t\t + \ 1981-06-27\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC1506478\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:332344\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Harrison, + A. R.\n\t\t\t\t Rose, G A\n\t\t\t\t + \ Kasidas, G P\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1506478\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da988f49d057fab0ec0685d2ad71868c\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Author's + Replay\n\t\t\t\t AUTHOR'S REPLAY\n\t\t\t\t + \ 2013-01-01\n\t\t\t\t Polish Urological + Association\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3921853\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.5173/ceju.2013.01.art33\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2917178\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Felberg, + Karina\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3921853\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::dcd954e5c175806832525aab88f07f71\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Bacteriology\n\t\t\t\t + \ Heteroresistance to Vancomycin in Enterococcus faecium\n\t\t\t\t + \ 2001-09-01\n\t\t\t\t American Society + for Microbiology\n\t\t\t\t eng\n\t\t\t\t + \ This study presents the first report of vancomycin heteroresistance + in an Enterococcus faecium isolate from a patient. The original isolate was + susceptible in vitro to vancomycin. E-tests showed growth of subcolonies in + a zone of inhibition with a vancomycin MIC of >256 \u03BCg/ml. Both the + susceptible and resistant colonies were from the same strain as determined + by PFGE, and both contained the vanA gene as determined by PCR.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC88352\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:204096\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Donabedian, + Susan\n\t\t\t\t Chow, Joseph W.\n\t\t\t\t + \ Brown, William\n\t\t\t\t Hershberger, + Ellie\n\t\t\t\t Zervos, Marcus J.\n\t\t\t\t + \ Alam, M. Rabiul\n\t\t\t\t Gordon, + James\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC88352\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::dcd96b5f0f43ced92b8a0ca206267499\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Original + Articles\n\t\t\t\t CHALLENGE! Visco-elastic heel + supports\n\t\t\t\t 1982-03-01\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC1858828\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:843244\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Sperryn, + Peter\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1858828\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::dcf2283bd6433366f06de1905e53e50c\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Nucleotide + sequences of the Chlorella ellipsoidea chloroplast genes for tRNA(ArgACG) + and tRNA(SerGCU).\n\t\t\t\t 1989-06-12\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC317946\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:34112\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Yamada, + T.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC317946\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d7d05107f108b9adbf4bcce2ed4b8d2e\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Physiology + and Metabolism\n\t\t\t\t Effect of Glycine on Thiazole + Biosynthesis in Escherichia coli\n\t\t\t\t 1970-03-01\n\t\t\t\t + \ eng\n\t\t\t\t Glycine was + found to replace thiamine thiazole for the growth of the thiazoleless mutant + of Escherichia coli; it also stimulated the production of thiamine thiazole + by washed cell suspensions of the mutant.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC250430\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:452118\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Iwashima, + Akio\n\t\t\t\t Nose, Yoshitsugu\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC250430\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d999a60bbd55678b5c6666e5e700657f\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Human + and Medical Genetics\n\t\t\t\t Interleukin-8-251T + > A, Interleukin-1\u03B1-889C > T and Apolipoprotein E polymorphisms + in Alzheimer\u2019s disease\n\t\t\t\t 2011-01-01\n\t\t\t\t + \ Sociedade Brasileira de Gen\xE9tica\n\t\t\t\t + \ eng\n\t\t\t\t An inflammatory + process has been involved in numerous neurodegenerative disorders such as + Parkinson\u2019s disease, stroke and Alzheimer\u2019s disease (AD). In AD, + the inflammatory response is mainly located in the vicinity of amyloid plaques. + Cytokines, such as interleukin-8 (IL-8) and interleukin-1\u03B1 (IL-1\u03B1), + have been clearly involved in this inflammatory process. Polymorphisms of + several interleukin genes have been correlated to the risk of developing AD. + The present study investigated the association of AD with polymorphisms IL-8 + -251T > A (rs4073) and IL-1\u03B1-889C > T (rs1800587) and the interactive + effect of both, adjusted by the Apolipoprotein E genotype. 199 blood samples + from patients with AD, 146 healthy elderly controls and 95 healthy young controls + were obtained. DNA samples were isolated from blood cells, and the PCR-RFLP + method was used for genotyping. The genotype distributions of polymorphisms + IL-8, IL-1\u03B1 and APOE were as expected under Hardy-Weinberg equilibrium. + The allele frequencies did not differ significantly among the three groups + tested. As expected, the APOE4 allele was strongly associated with AD (p < + 0.001). No association of AD with either the IL-1\u03B1 or the IL-8 polymorphism + was observed, nor was any interactive effect between both polymorphisms. These + results confirm previous studies in other populations, in which polymorphisms + IL-8 -251T > A and IL-1\u03B1-889C > T were not found to be risk factors + for AD.\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2115904\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.1590/S1415-47572010005000098\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC3085352\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t dos + Reis, Nathali Mattiuzo\n\t\t\t\t de L\xE1bio, + Roger Willian\n\t\t\t\t Rasmussen, Lucas Trevizani\n\t\t\t\t + \ Mazzotti, Diego Robles\n\t\t\t\t Vendramini, + Alex Augusto\n\t\t\t\t de Arruda Cardoso Smith, + Mar\xEDlia\n\t\t\t\t de Souza Pinhel, Marcela + Augusta\n\t\t\t\t Minett, Thais\n\t\t\t\t + \ Pay\xE3o, Spencer Luiz Marques\n\t\t\t\t Bertolucci, + Paulo Henrique Ferreira\n\t\t\t\t Souza, Dorot\xE9ia + Rossi Silva\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3085352\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8422590\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8304236\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15270199\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16914858\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18717723\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10953177\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19155622\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12666129\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16606766\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::91d606143cf98a70517b691f901f8ce2\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2529544\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17195884\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/1164215\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12662377\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::4ba8ac1c88c64a10433f5df5122d1c4f\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15377701\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2341813\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18709454\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15083298\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2864910\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12794386\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/6610841\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9203678\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18334755\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15079806\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16378839\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18410513\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18057554\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16733901\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10714678\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d99c8505851904b716ada59a886df41e\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t General + Articles and News\n\t\t\t\t Obituary: G. W. DRYLAND, + M.B., B.Ch\n\t\t\t\t 1960-03-12\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC1966889\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:531518\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1966889\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d9adca640e7474da5a92a574771ca9cb\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Original + Article\n\t\t\t\t Non-invasive intraductal papillary + neoplasms of the common bile duct: a clinicopathologic study of six cases\n\t\t\t\t + \ 2012-09-05\n\t\t\t\t e-Century Publishing + Corporation\n\t\t\t\t eng\n\t\t\t\t + \ Recently, several studies of intraductal papillary neoplasms + (IPN) of the biliary tracts have been reported in the liver, but there have + been only one study of them in the common bile duct (CBD). The author reviewed + 34 archival pathologic materials of surgically resected specimens containing + CBD tumors. Results: Six cases (18%) of IPN of the CBD were found. All cases + were non-invasive intraductal papillary carcinomas (IPC). The age of the patients + with IPC ranged from 49 to 77 years with a mean of 67 years. The male to female + ratio was 4:2. The initial symptoms were abdominal pain in 2 cases, abdominal + discomfort in 1 case, and obstructive jaundice in 3 cases. Imaging modalities + including US, CT, MRI, and ERCP revealed the CBD luminal tumors and biliary + dilations in all cases. Surgical procedures were pancreaticoduodenectomy in + 4 cases and segmental resection in 2 cases. The survival is relatively good; + five patients are now alive, and one died of other disease. Grossly, all the + 6 IPC showed intraductal papillary tumors. No mucus was found. Histologically, + papillary proliferation of atypical cells with hyperchromatic nuclei regarded + as malignant was recognized. The papillary proliferation was accompanied by + fine fibrovascular cores in all cases. No stromal invasion was recognized, + but lateral non-papillary in situ extension was recognized in 5 cases. Tubular + formations were present in some areas in all cases. Goblet cells were present + in 5 cases. No mucous hypersecretion was recognized. In one case, the tumor + was composed of malignant oncocytes, and was regarded as intraductal oncocytic + papillary carcinoma. Immunohistochemically, p53 expression was present in + 5 cases, and Ki-67 labeling ranged from 30% to 70%. The author presented clinicopathologic + findings of 6 cases of non-invasive IPC of the CBD.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3438766\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2444242\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Terada, + Tadashi\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3438766\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d9c49741a0b191082ee4a9ab51f6e402\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Editorial\n\t\t\t\t + \ Childhood leukaemia and nuclear installations: the long and + winding road\n\t\t\t\t 2014-10-07\n\t\t\t\t + \ Nature Publishing Group\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/doi/10.1038/bjc.2014.517\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:3426065\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC4453740\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Wakeford, + R.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC4453740\n\t\t\t\t + \ http://europepmc.org/abstract/MED/25290088\n\t\t\t\t + \ http://dx.doi.org/10.1038/bjc.2014.517\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::464b01bcf6733d8fd5cb3dc55eeb3178\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8051520\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/bjc.2014.357\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8107860\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::ca315316b128d9ad43fbddcc28abea5b\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2107892\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::37cfa5af841b1ee0f302d5c4b00d9543\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17589605\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::f2406d4508a251406e35d087be1b69b3\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21063418\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2904050\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::1907fb44d957fdb2409256d61dcc3112\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8490337\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::517816050707cb28b8df02e7dbd4b3ae\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22955857\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od______3071::9853bb7b17030bb9fca1930d09c5afcf\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/24938793\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::75594835e0d0e7dce8bd22b8d18e3a5c\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15121523\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20309707\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/14750684\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/23296257\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::d9c49741a0b191082ee4a9ab51f6e402\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/24477409\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d9c7f201412227faed7755f0664557d4\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Neuroticism, Negative Affect, and Negative Affect Instability: + Establishing Convergent and Discriminant Validity Using Ecological Momentary + Assessment\n\t\t\t\t 2009-12-01\n\t\t\t\t + \ eng\n\t\t\t\t Few investigations + have examined the role of affective instability within a broad model of general + personality functioning. The present study employed self-report and ecological + momentary assessments (EMA) to examine the relations between self-reported + Five-Factor Model Neuroticism, EMA average negative affect, and EMA negative + affect instability. Results suggest that Neuroticism and negative affect instability + are related yet distinct constructs, and that Neuroticism better represents + average negative affect across time. Results also suggest that negative affect + instability is related to low Agreeableness and specific externalizing facets + of Neuroticism, such as Angry Hostility and Impulsiveness. The implications + of these findings and potential areas for future research are discussed.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2760940\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1884496\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Vachon, + David D.\n\t\t\t\t Miller, Drew J.\n\t\t\t\t + \ Lynam, Donald R\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2760940\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da02e06b6e1815250f6c0b5c5e7c0e2b\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Role of NFkappaB in the mortality + of sepsis.\n\t\t\t\t 1997-09-01\n\t\t\t\t + \ eng\n\t\t\t\t Binding activity + for nuclear factor kappa B (NFkappaB) consensus probes was studied in nuclear + extracts from peripheral blood mononuclear cells of 15 septic patients (10 + surviving and 5 not surviving). Nonsurvivors could be distinguished from survivors + by an increase in NFkappaB binding activity during the observation period + (P < 0.001). The increase in NFkappaB binding activity was comparable to + the APACHE-II score as a predictor of outcome. Intravenous somatic gene transfer + with an expression plasmid coding for IkappaBalpha was used to investigate + the role of members of the NFkappaB family in a mouse model of endotoxemia. + In this model, increased NFkappaB binding activity was present after injection + of LPS. Intravenous somatic gene transfer with IkappaBalpha given before LPS + attenuated renal NFkappaB binding activity and increased survival. Endothelial + cells and monocytes/macrophages were the major target cells for somatic gene + transfer, transfected with an average transfection efficiency of 20-35%. Tissue + factor, a gene under regulatory control of NFkappaB, was induced by LPS. Somatic + gene transfer with a reporter plasmid containing the functional tissue factor + promoter demonstrated NFkappaB-dependent stimulation by LPS. Intravenous somatic + gene transfer with IkappaBalpha reduced LPS-induced renal tissue factor expression, + activation of the plasmatic coagulation system (decrease of thrombin-antithrombin + III complexes) and renal fibrin/fibrinogen deposition. Somatic gene transfer + with an expression plasmid with tissue factor cDNA in the antisense direction + (in contrast to sense or vector alone) also increased survival. Furthermore, + antisense tissue factor decreased renal tissue factor expression and the activation + of the plasmatic coagulation system.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC508272\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1323154\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Jllmer, + T\n\t\t\t\t Nawroth, P. P.\n\t\t\t\t + \ Bierhaus, A\n\t\t\t\t M\xE4nnel, + D.\n\t\t\t\t Ziegler, R.\n\t\t\t\t + \ Waldherr, R\n\t\t\t\t Martin, + E.\n\t\t\t\t B\xF6hrer, H\n\t\t\t\t + \ Zimmermann, T\n\t\t\t\t F. Qiu\n\t\t\t\t + \ B\xF6ttiger, B W\n\t\t\t\t Zhang, + Y\n\t\t\t\t Stern, D. M.\n\t\t\t\t + \ Saeger, H. D.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC508272\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da098ab40f0c64a76a8ba7d89fb1e836\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Retrospective serological survey + of antibodies to porcine circovirus type 1 and type 2.\n\t\t\t\t + \ 2000-07-01\n\t\t\t\t eng\n\t\t\t\t + \ A retrospective serological survey was performed to determine + the presence of antibodies to porcine circovirus type 1 (PCV1) and porcine + circovirus type 2 (PCV2) in serum samples collected from sows at slaughterhouses + in Canada in 1985, 1989, and 1997. Each serum sample was tested by indirect + immunofluorescence on PCV-free PK15 cells, on PCV1-infected PK15 cells and + on PCV2-infected PK15 cells. For the 3 years studied, sera positive to PCV1 + and PCV2 were identified and the number of sera positive for PCV2 was greater + than the number of sera positive for PCV1. The results indicated 1) that PCV2 + appears to be the main PCV type circulating in the Canadian pig population, + 2) that PCV2 had been circulating in the Canadian pig population at least + 10 years before the postweaning multisystemic wasting syndrome (PMWS) was + reported, and 3) that serological evaluation using PCV1 underestimates the + seroprevalence of PCV2.\n\t\t\t\t Europe PubMed + Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC1189611\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:168381\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Magar, + R\n\t\t\t\t M\xFCller, P.\n\t\t\t\t + \ Larochelle, R\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1189611\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da18f1a5f1819fbe9697ffc392abc3be\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Bacillus anthracis HssRS signaling to HrtAB regulates heme resistance + during infection\n\t\t\t\t 2009-05-01\n\t\t\t\t + \ eng\n\t\t\t\t Bacillus anthracis + proliferates to high levels within vertebrate tissues during the pathogenesis + of anthrax. This growth is facilitated by the acquisition of nutrient iron + from host heme. However, heme acquisition can lead to the accumulation of + toxic amounts of heme within B. anthracis. Here, we show that B. anthracis + resists heme toxicity by sensing heme through the HssRS two-component system, + which regulates expression of the heme-detoxifying transporter HrtAB. In addition, + we demonstrate that B. anthracis exhibits elevated HssRS function compared + to its evolutionary relative S. aureus. Elevated heme sensing is likely required + by B. anthracis due to the significant heme sensitivity exhibited by members + of the genus Bacilli. We also demonstrate that B. anthracis depends on conserved + residues within the previously uncharacterized sensing domain of the histidine + kinase HssS for HssS function. Finally, we show that the heme- and HssRS-regulated + hrtAB promoter is activated in a murine model of anthrax. These results demonstrate + the evolutionary conservation of heme sensing among multiple Gram-positive + bacteria and begin to provide a mechanistic explanation for the heme resistance + of B. anthracis. Further, these data suggest that heme stress is experienced + by bacterial pathogens during infection.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2891670\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1990682\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Skaar, + Eric P\n\t\t\t\t Stauff, Devin L.\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC2891670\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da3314a516635145db7f3cd8865604ff\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Genetics + and Molecular Biology\n\t\t\t\t Volatilization of + Mercuric Chloride by Mercury-Resistant Plasmid-Bearing Strains of Escherichia + coli, Staphylococcus aureus, and Pseudomonas aeruginosa\n\t\t\t\t + \ 1973-02-01\n\t\t\t\t eng\n\t\t\t\t + \ Several bacterial strains carrying genes determining mercury + resistance on naturally occurring plasmids will convert 10\u22125m Hg2+ (chloride) + to a form of mercury which is volatile and soluble in organic solvents. The + volatilization activity is induced by exposure to HgCl2.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC285330\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:462886\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Lewis, + Elaine\n\t\t\t\t Summers, Anne O.\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC285330\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da52b63ee37476cb8fe0b83a46012a61\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Thrombosis + and Hemostasis\n\t\t\t\t Activated protein C inhibits + high mobility group box 1 signaling in endothelial cells\n\t\t\t\t + \ 2011-10-06\n\t\t\t\t American Society + of Hematology\n\t\t\t\t eng\n\t\t\t\t + \ A pathogenic role for high-mobility group box 1 (HMGB1) + protein has been postulated in severe sepsis. Activated protein C (APC) is + the only drug approved by the Food and Drug Administration for severe sepsis; + however, its effect on HMGB1 signaling has never been investigated. Here, + we monitored the effect of APC on the lipopolysaccharide-mediated release + of HMGB1 and the HMGB1-mediated modulation of proinflammatory responses in + HUVECs. APC potently inhibited the release of HMGB1 and down-regulated the + adhesion of the monocytic cell line, THP-1, to HMGB1-activated endothelial + cells. HMGB1 up-regulated proinflammatory responses by interacting with 3 + pathogen-related pattern recognition receptors: TLR2 and TLR4 and the receptor + for advanced glycation end products. APC not only inhibited HMGB1 release + but also down-regulated the cell surface expression of all 3 HMGB1 receptors + in endothelial cells. The protective effects of APC were mediated through + endothelial cell protein C receptor (EPCR) and protease-activated receptor + 1 (PAR-1). Interestingly, a thrombin derivative containing the Gla-domain + of APC recapitulated all protective effects of APC with a 20- to 50-fold higher + efficacy. These results suggest that the EPCR- and PAR-1\u2013dependent protective + effects of APC in severe sepsis may partially be mediated through the inhibition + of HMGB1 signaling and that the chimeric thrombin mutant has potential therapeutic + utility for severe sepsis.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3193270\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2456243\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Alireza + R. Rezaie\n\t\t\t\t Bae, Jong-Sup\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC3193270\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da65aa76df07af6e3d12a8093b9beba1\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Isolation and Clonal Analysis of Satellite Cells from Chicken + Pectoralis Muscle\n\t\t\t\t 1987-01-01\n\t\t\t\t + \ eng\n\t\t\t\t Satellite + cells, liberated from the breast muscle of young adult chickens by sequential + treatment with collagenase and trypsin, were fractionated by Percoll density + centrifugation to remove myofibril fragments and cell debris which otherwise + heavily contaminate the preparation. This procedure allowed direct measurements + of cell yields (1.5\u20134 \xD7 105 cells/g tissue), plating efficiencies + (27\u201340%) and identification of single cells in culture. In mass cultures, + satellite cells gave rise to myotubes on the fifth day, and the progeny of + these cells were sequentially passaged several times without losing myogenic + traits. In clonal studies, over 90% of the satellite cells gave rise to large + clones of which more than 99% were myogenic as demonstrated by the appearance + of myotubes. The results obtained with satellite cells differ from observations + made using embryonic muscle cell preparation from chicks. In the embryonic + system massive formation of myotubes was observed following the third day + of culture; sequential subculturing led to overgrowth of fibroblast-like cells + following the first passage; and cells gave rise to both small myogenic clones + (up to 16 terminally differentiated cells per clone) and non-myogenic clones + in addition to large myogenic clones. We conclude that the isolated satellite + cells represent a homogeneous cell population and reside in a stem cell compartment.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC4128172\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:3097351\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Yablonka-Reuveni, + Zipora\n\t\t\t\t Nameroff, Mark\n\t\t\t\t + \ Quinn, LeBris S.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC4128172\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da793789d627505022cb692015814d96\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Asymmetries in the Hippocampus and Amygdala of Chimpanzees (Pan + troglodytes)\n\t\t\t\t 2004-12-01\n\t\t\t\t + \ eng\n\t\t\t\t Magnetic resonance + imaging was used to measure the hippocampal and amygdalar volumes of 60 chimpanzees + (Pan troglodytes). An asymmetry quotient (AQ) was then used to calculate the + asymmetry for each of the structures. A one-sample t test indicated that there + was a population-level right hemisphere asymmetry for the hippocampus. There + was no significant population-level asymmetry for the amygdala. An analysis + of variance using sex and rearing history as between-group variables showed + no significant main effects or interaction effects on the AQ scores; however, + males were more strongly lateralized than females. Several of these findings + are consistent with results found in the human literature.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2025580\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1827740\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Hani + D. Freeman\n\t\t\t\t Cantalupo, Claudio\n\t\t\t\t + \ Hopkins, William D.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2025580\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da8394bfdd7e91ff44999acfd82a07bc\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ A winding road to origin discovery\n\t\t\t\t 2010-01-01\n\t\t\t\t + \ eng\n\t\t\t\t Studies in + our laboratory over the last three decades have shown that the Chinese hamster + dihydrofolate reductase (DHFR) origin of replication corresponds to a broad + zone of inefficient initiation sites distributed throughout the spacer between + the convergently transcribed DHFR and 2BE2121 genes. It is clear from mutational + analysis that none of these sites is genetically required for controlling + origin activity. However, the integrity of the promoter of the DHFR gene is + needed to activate the downstream origin, while the 3\u2032 processing signals + prevent invasion and inactivation of the downstream origin by transcription + forks. Several other origins in metazoans have been shown to correspond to + zones of inefficient sites, while a different subset appears to be similar + to the fixed replicators that characterize origins in S. cerevisiae and lower + organisms. These observations have led us to suggest a model in which the + mammalian genome is dotted with a hierarchy of degenerate, redundant, and + inefficient replicators at intervals of a kilobase or less, some of which + may have evolved to be highly circumscribed and efficient. The activities + of initiation sites are proposed to be largely regulated by local transcription + and chromatin architecture. Recently, we and others have devised strategies + for identifying active origins on a genome-wide scale in order to define their + distributions between fixed and dispersive origin types and to detect relationships + among origins, genes, and epigenetic markers. The global pictures emerging + are suggestive but far from complete and appear to be plagued by some of the + same uncertainties that have led to conflicting views of individual origins + in the past (particularly DHFR). In this paper, we will trace the history + of origin discovery in mammalian genomes, primarily using the well-studied + DHFR origin as a model, because it has been analyzed by nearly every available + origin mapping technique in several different laboratories, while many origins + have been identified by only one. We will address the strengths and shortcomings + of the various methods utilized to identify and characterize origins in complex + genomes and will point out how we and others were sometimes led astray by + false assumptions and biases, as well as insufficient information. The goal + is to help guide future experiments that will provide a truly comprehensive + and accurate portrait of origins and their regulation. After all, in the words + of George Santayana, \u201CThose who do not learn from history are doomed + to repeat it.\u201D\n\t\t\t\t Europe PubMed + Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2904547\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1956093\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Mesner, + Larry D\n\t\t\t\t Hamlin, Joyce L\n\t\t\t\t + \ Dijkwel, Pieter A.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2904547\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da8dfbf9003036206b121a5cdc25a001\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Articles\n\t\t\t\t + \ THE SYNTHESIS OF AMINO ACIDS BY ESCHERICHIA COLI IN PURE CULTURES1\n\t\t\t\t + \ 1949-10-01\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC385653\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:91594\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Dunlop, + Stuart G.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC385653\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::da98a0528c69d18fe5b71da8d47f63f1\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Articles\n\t\t\t\t Spatially Resolved Genomic, Stable + Isotopic, and Lipid Analyses of a Modern Freshwater Microbialite from Cuatro + Ci\xE9negas, Mexico\n\t\t\t\t 2012-07-01\n\t\t\t\t + \ Mary Ann Liebert, Inc.\n\t\t\t\t eng\n\t\t\t\t + \ Microbialites are biologically mediated carbonate deposits + found in diverse environments worldwide. To explore the organisms and processes + involved in microbialite formation, this study integrated genomic, lipid, + and both organic and inorganic stable isotopic analyses to examine five discrete + depth horizons spanning the surface 25\u2009mm of a modern freshwater microbialite + from Cuatro Ci\xE9negas, Mexico. Distinct bacterial communities and geochemical + signatures were observed in each microbialite layer. Photoautotrophic organisms + accounted for approximately 65% of the sequences in the surface community + and produced biomass with distinctive lipid biomarker and isotopic (\u03B413C) + signatures. This photoautotrophic biomass was efficiently degraded in the + deeper layers by heterotrophic organisms, primarily sulfate-reducing proteobacteria. + Two spatially distinct zones of carbonate precipitation were observed within + the microbialite, with the first zone corresponding to the phototroph-dominated + portion of the microbialite and the second zone associated with the presence + of sulfate-reducing heterotrophs. The coupling of photoautotrophic production, + heterotrophic decomposition, and remineralization of organic matter led to + the incorporation of a characteristic biogenic signature into the inorganic + CaCO3 matrix. Overall, spatially resolved multidisciplinary analyses of the + microbialite enabled correlations to be made between the distribution of specific + organisms, precipitation of carbonate, and preservation of unique lipid and + isotopic geochemical signatures. These findings are critical for understanding + the formation of modern microbialites and have implications for the interpretation + of ancient microbialite records. Key Words: Microbial ecology\u2014Microbe-mineral + interactions\u2014Microbial mats\u2014Stromatolites\u2014Genomics. Astrobiology + 12, 685\u2013698.\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC3426887\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2691777\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Nitti, + Anthony\n\t\t\t\t Siefert, Janet\n\t\t\t\t + \ Daniels, Camille A.\n\t\t\t\t Hollander, + David\n\t\t\t\t Souza, Valeria\n\t\t\t\t + \ Breitbart, Mya\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3426887\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::daab63149474c725aa2133db08ee0647\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ An Efficient Simulation Budget Allocation Method Incorporating + Regression for Partitioned Domains*\n\t\t\t\t 2014-05-01\n\t\t\t\t + \ eng\n\t\t\t\t Simulation + can be a very powerful tool to help decision making in many applications but + exploring multiple courses of actions can be time consuming. Numerous ranking + & selection (R&S) procedures have been developed to enhance the simulation + efficiency of finding the best design. To further improve efficiency, one + approach is to incorporate information from across the domain into a regression + equation. However, the use of a regression metamodel also inherits some typical + assumptions from most regression approaches, such as the assumption of an + underlying quadratic function and the simulation noise is homogeneous across + the domain of interest. To extend the limitation while retaining the efficiency + benefit, we propose to partition the domain of interest such that in each + partition the mean of the underlying function is approximately quadratic. + Our new method provides approximately optimal rules for between and within + partitions that determine the number of samples allocated to each design location. + The goal is to maximize the probability of correctly selecting the best design. + Numerical experiments demonstrate that our new approach can dramatically enhance + efficiency over existing efficient R&S methods.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC4055954\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.1016/j.automatica.2014.03.011\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:3377765\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Brantley, + Mark W.\n\t\t\t\t Lee, Loo Hay\n\t\t\t\t + \ Chen, Chun-Hung\n\t\t\t\t Xu, + Jie\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC4055954\n\t\t\t\t + \ http://europepmc.org/abstract/MED/24936099\n\t\t\t\t + \ http://dx.doi.org/10.1016/j.automatica.2014.03.011\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::daaca267e3074856530561e98ff88c2e\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Papers\n\t\t\t\t The use of nerve and muscle biopsy + in the diagnosis of vasculitis: a 5 year retrospective study\n\t\t\t\t + \ 2008-09-26\n\t\t\t\t BMJ Publishing + Group\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmid/18819942\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1935702\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.1136/jnnp.2008.151126\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC2582330\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Ginsberg, + L\n\t\t\t\t King, R.H.M.\n\t\t\t\t + \ Groves, M.\n\t\t\t\t Blake, J.\n\t\t\t\t + \ Bennett, D L H\n\t\t\t\t Orrell, + R W\n\t\t\t\t Reilly, M M\n\t\t\t\t + \ Holton, J.L.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2582330\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15806339\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16297843\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/4037764\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2839104\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/1657271\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12963752\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/3651797\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8931569\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16519779\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8129773\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15367863\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10980725\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12395371\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/1965205\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/7671454\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15015005\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::b2f782d42e29421b31ed5edaf2056176\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/3025376\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8813273\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15365139\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2557297\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10714582\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19078569\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10094252\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::edcd53dbf9ecd0b008321b4b784ce680\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17550992\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::dab2906ab1ac981b83111907cbc20fc4\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research\n\t\t\t\t + \ Down-regulation of miR-675-5p contributes to tumor progression + and development by targeting pro-tumorigenic GPR55 in non-small cell lung + cancer\n\t\t\t\t 2015-04-01\n\t\t\t\t BioMed + Central\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:3358248\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.1186/s12943-015-0342-0\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC4392735\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t GAO, + YANG\n\t\t\t\t Chen, Zhuchu\n\t\t\t\t + \ Chen, Wei\n\t\t\t\t SHAN, BIN\n\t\t\t\t + \ Li, Bin\n\t\t\t\t Zhang, ChunFang\n\t\t\t\t + \ Zhou, Yanwu\n\t\t\t\t Deng, XiYun\n\t\t\t\t + \ He, Dan\n\t\t\t\t DUAN, CHAOJUN\n\t\t\t\t + \ Hong, Jidong\n\t\t\t\t Wang, Jun\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC4392735\n\t\t\t\t + \ http://dx.doi.org/10.1186/s12943-015-0342-0\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/nature02871\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15372042\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/onc.2010.402\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20818416\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:dedup_wf_001::6be91740c4d9208de190de056b3c189c\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1186/1476-4598-7-81\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18947422\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:dedup_wf_001::bc13f3f04df2a85c5c6a054cc1851fa9\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/nature08460\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19847166\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/S0092-8674(04)00045-5\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/14744438\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1261/rna.351707\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17237358\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/nrc1997\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17060945\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/j.ajpath.2012.11.019\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/23306155\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::83d7be030b5a200a25d3068351bfaf94\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1371/journal.pone.0088022\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/24505359\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::08b763b82b99a7157208119f9f9ca810\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1007/s10555-010-9204-9\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20130964\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1002/jcb.24480\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/23255405\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1615/JEnvironPatholToxicolOncol.2013005859\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/23394450\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1111/j.1476-5381.2010.00743.x\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20590578\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/j.ccr.2012.03.007\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22439939\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1096/fj.08-108670\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18757503\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1245/s10434-013-3106-3\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/23864307\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/onc.2010.502\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21057532\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.3322/caac.20107\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21296855\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1002/ijc.29041\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/24961907\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::deb8f65f5ebae9a29db4d54561f5bb5d\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/ncb2521\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22684254\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/j.devcel.2006.09.009\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17011485\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::54985b5cdb9e035882178d218bdbc23e\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/j.cell.2007.04.040\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17604727\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/j.gene.2012.09.093\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/23036707\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::f375cc45864be0dd547979118e1bc4c4\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/24810858\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/nature03315\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15685193\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::573b33d174e659c08f9c4a31c8841d11\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/sj.bjc.6605901\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20859290\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/nature03702\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15944708\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1093/carcin/bgs100\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22331473\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/j.gene.2012.06.008\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22732573\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/j.bbrc.2007.08.078\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17765871\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::8d158cb5ea787b4f13edf90003ef1bc6\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/j.bcp.2013.11.020\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/24355564\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/onc.2012.278\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22751111\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/onc.2010.417\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20838378\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/j.tips.2011.01.005\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21367464\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::1ed494717edf34091221f66f2ed973a4\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1136/jcp.2010.085621\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21471143\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1074/jbc.M802786200\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18499657\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::457d7f83a30c8818f3dcf7ed92f26b01\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1371/journal.pone.0086295\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/24466011\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::9ef3cc976c346c6e28afff13a91b89be\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1371/journal.pone.0030240\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22279574\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/nrg3471\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/23817310\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1158/1078-0432.CCR-13-1221\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/24602839\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1093/carcin/bgp181\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19926638\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::c881ae6fa2eb8e111011d82cf87f7ba3\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/j.cell.2009.02.005\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19239879\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1038/onc.2013.108\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/23584484\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17094486\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1111/febs.12902\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/24988946\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/j.bbrc.2013.12.126\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/24388988\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::dab87b6dcfc9d3606814d79882f85146\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Identification of immunoreactive + antigens of human papillomavirus type 6b by using Escherichia coli-expressed + fusion proteins.\n\t\t\t\t 1988-06-01\n\t\t\t\t + \ eng\n\t\t\t\t Human papillomavirus + (HPVs) infect the genital epithelium and are found in proliferative lesions + ranging from benign condylomata to invasive carcinomas. The immunological + response to these infections is poorly understood because of the lack of purified + viral antigens. In this study, bacterially derived fusion proteins expressing + segments of all the major open reading frames (ORFs) of HPV type 6b (HPV-6b) + have been used in Western blot (immunoblot) assays to detect antibodies directed + against HPV-encoded proteins. The most striking reactivities present in sera + from patients with genital warts were to the HPV-6b L1 ORF protein and, to + a lesser extent, to the HPV-6b L2 ORF protein. Two cases of reactivity to + HPV-6b E2 ORF were observed, but no reactivities were seen with other HPV-6b + constructs. Two sera reacted with the HPV-16 L2 fusion protein, and two sera + reacted with the HPV-16 E4 protein. The antibodies directed against the HPV-6b + fusion proteins showed no cross-reactivity with comparable regions of the + HPV-16 ORFs. This assay provides a useful approach for further studies of + HPV serology.\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC253307\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1472487\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Firzlaff, + J M\n\t\t\t\t Jenison, S A\n\t\t\t\t + \ Galloway, D A\n\t\t\t\t Langenberg, + A.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC253307\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::dab99b77d8161f271bce2ff847aae536\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Binding of ATP to TK1-like Enzymes Is Associated with a Conformational + Change in the Quaternary Structure\n\t\t\t\t 2007-03-15\n\t\t\t\t + \ eng\n\t\t\t\t Human thymidine + kinase 1 (hTK1) and structurally related TKs from other organisms catalyze + the initial phosphorylation step in the thymidine salvage pathway. Though + ATP is known to be the preferred phosphoryl donor for TK1-like enzymes, its + exact binding mode and effect on the oligomeric state has not been analyzed. + Here we report the structures of hTK1 and of the Thermotoga maritima thymidine + kinase (TmTK) in complex with the bisubstrate inhibitor TP4A. The TmTK-TP4A + structure reveals that the adenosine moiety of ATP binds at the subunit interface + of the homotetrameric enzyme and that the majority of the ATP-enzyme interactions + occur between the phosphate groups and the P-loop. In the hTK1 structure the + adenosine group of TP4A exhibited no electron density. This difference between + hTK1 and TmTK is rationalized by a difference in the conformation of their + quaternary structure. A more open conformation, as seen in the TmTK-TP4A complex + structure, is required to provide space for the adenosine moiety. Our analysis + supports the formation of an analogous open conformation in hTK1 upon ATP + binding.\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC1899836\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1345869\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Konrad, + Manfred\n\t\t\t\t Lavie, Arnon\n\t\t\t\t + \ Lutz, Stefan\n\t\t\t\t Segura-Pe\xF1a, + Dario\n\t\t\t\t Monnerjahn, Christian\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC1899836\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::dad7902e06f3c4fcdd5cd41fde76a7f9\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Circulating levels of sulphasalazine + and its metabolites and their relation to the clinical efficacy of the drug + in ulcerative colitis.\n\t\t\t\t 1980-08-01\n\t\t\t\t + \ eng\n\t\t\t\t One hundred + and eighty-five patients with ulcerative colitis have been studied serially + while receiving regular maintenance treatment with sulphasalazine (SASP) in + a dose of 0.5 g four times daily. The circulating levels of the drug and its + principal metabolites during remission do not influence the liability to relapse. + When relapse does occur, the circulating level of sulphapyridine falls and + remains depressed until remission occurs. This fall during a relapse is most + pronounced when the patient suffers from universal colitis and is least marked + in cases of distal colitis.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC1419120\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:467708\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Truelove, + S C\n\t\t\t\t A K Azad Khan\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC1419120\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::dad9cbc142a6d5677097d1f56cca1b3c\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ A Secondary Gate As a Mechanism for Inhibition of the M2 Proton + Channel by Amantadine\n\t\t\t\t 2008-05-14\n\t\t\t\t + \ eng\n\t\t\t\t The mechanism + of inhibition of the influenza A virus M2 proton channel by the antiviral + drug amantadine has been under intense investigation. The importance of a + mechanistic understanding is heightened by the prevalence of amantadine-resistant + mutations. To gain mechanistic insight at the molecular level, we carried + out extensive molecular dynamics simulations of the tetrameric M2 proton channel + in both apo and amantadine-bound forms in a lipid bilayer. The simulation + of the apo form revealed that Val27 from the four M2 subunits can form a secondary + gate near the channel entrance and break the water wire in the channel pore. + This gate arises from physical occlusion and the elimination of hydrogen-bonding + partners for water molecules. In the presence of amantadine, the secondary + gate formed by Val27 and the drug molecule lying just below form an extended + blockage, which breaks the water wire throughout the simulation. The location + and orientation of amantadine inside of the channel pore as found in our simulation + are supported by a host of experimental observations. Our study suggests a + novel role for Val27 in the inhibition of the M2 proton channel by amantadine.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3801206\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2792791\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Yi, + Myunggi\n\t\t\t\t ZHOU, HUAN-XIANG\n\t\t\t\t + \ Cross, Timothy A\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3801206\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::dada283eece4e3624bc68933c5c09e2c\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Earth + Science\n\t\t\t\t On the Helmert-blocking technique: + its acceleration by block Choleski decomposition and formulae to insert observations + into an adjusted network\n\t\t\t\t 2015-04-22\n\t\t\t\t + \ The Royal Society Publishing\n\t\t\t\t eng\n\t\t\t\t + \ The Helmert-blocking technique is a common approach to + adjust large geodetic networks like Europeans and Brazilians. The technique + is based upon a division of the network into partial networks called blocks. + This way, the global network adjustment can be done by manipulating these + blocks. Here we show alternatives to solve the block system that arises from + the application of the technique. We show an alternative that optimizes its + implementation as the elapsed processing time is decreased by about 33%. We + also show that to insert observations into an adjusted network it is not necessary + to readjust the whole network. We show the formulae to insert new observations + into an adjusted network that are more efficient than simply readjusting the + whole new network.\n\t\t\t\t Europe PubMed + Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:3425898\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.1098/rsos.140417\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC4448856\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Del + Rio, Eduardo\n\t\t\t\t de Oliveira, Leonardo\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC4448856\n\t\t\t\t + \ http://dx.doi.org/10.1098/rsos.140417\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d5a407d899a5ca3fbe3f76170411ada2\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Osteotomy as an indicator of antiseptic + surgical practice.\n\t\t\t\t 1994-04-01\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC1036843\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmid/8007752\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:224495\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Pennington, + T H\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1036843\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d5a84f29f157e5ad52ba5bf2b0d7e11e\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Evidence that the National Committee + for Clinical Laboratory Standards disk test is less sensitive than the screen + plate for detection of low-expression-class methicillin-resistant Staphylococcus + aureus.\n\t\t\t\t 1995-07-01\n\t\t\t\t eng\n\t\t\t\t + \ A low-expression-class methicillin-resistant Staphylococcus + aureus strain (strain 9302-2) was sent to 207 laboratories as part of the + bacteriology component of the Laboratory Proficiency Testing Program of Ontario. + An incorrect (susceptible) result was reported by 16 of 76 (21%) of laboratories + that used the National Committee for Clinical Laboratory standards disk test, + whereas 1 of 104 laboratories that used other methods reported an incorrect + result (P < 0.05). Experiments showed discrepancies in the disk test results + given by Mueller-Hinton agars from three manufacturers. We advise that laboratories + should use a low expression-class methicillin-resistant S. aureus isolate + as a control for the National Committee for Clinical Laboratory Standards + disk test.\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC228296\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:159676\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Richardson, + H.\n\t\t\t\t Mackenzie, A. M.\n\t\t\t\t + \ Wood, D.\n\t\t\t\t Lannigan, R.\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC228296\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d5abbb8c7c86e9c4127a9351cdc8815d\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Original + Research\n\t\t\t\t Glycemic Control, Coping, and + Internalizing and Externalizing Symptoms in Adolescents With Type 1 Diabetes: + A cross-lagged longitudinal approach\n\t\t\t\t 2010-03-31\n\t\t\t\t + \ American Diabetes Association\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2119452\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.2337/dc09-2017\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC2890333\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmid/20357383\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Seiffge-Krenke, + Inge\n\t\t\t\t Hampson, Sarah E.\n\t\t\t\t + \ Luyckx, Koen\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2890333\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16732028\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9028691\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::e54bee891656397467cc36169819cdd6\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19171719\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2283571\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/3224248\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/3385578\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::edc01fc4ec590383b5da6a21d25d9870\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19389814\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/6131280\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9063039\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2794185\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8410569\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19236405\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15161781\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:dedup_wf_001::a971f12502d316df76aa705fbaf545e3\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19196897\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18667479\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11293366\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/3562706\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8442570\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15616254\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d5bacb31e9142c453b8d49c7ba91e79e\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Articles\n\t\t\t\t + \ The Formol Titration of Bacteriological Media\n\t\t\t\t + \ 1923-05-01\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC379014\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:113683\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Brown, + J. Howard\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC379014\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d5cbd99946b0c12d3b4f2ff83c8261fd\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research\n\t\t\t\t + \ Differences in one-year health outcomes and resource utilization + by definition of prolonged mechanical ventilation: a prospective cohort study\n\t\t\t\t + \ 2007-01-01\n\t\t\t\t BioMed Central\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC2147069\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmid/17244364\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.1186/cc5667\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1358171\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Olsen, + Maren K\n\t\t\t\t Chelluri, Lakshmipathi\n\t\t\t\t + \ Lindquist, Jennifer H.\n\t\t\t\t Carson, + Shannon S\n\t\t\t\t Govert, Joseph A.\n\t\t\t\t + \ Cox, Christopher E.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2147069\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1378/chest.121.2.549\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11834671\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______645::44410900e9be1e98753e6f906b8df8db\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1001/jama.284.21.2762\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11105183\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1378/chest.118.4.1100\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11035684\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10228128\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1378/chest.120.3.928\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11555531\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/S0749-0704(02)00015-5\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12140908\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/0021-9681(87)90171-8\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/3558716\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1097/01.CCM.0000098029.65347.F9\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/14707560\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1001/jama.278.12.1001\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9307348\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15640633\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1378/chest.128.2.507\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16100132\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1097/01.CCM.0000164543.14619.00\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15942342\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1097/00003246-200212000-00008\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12483055\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1378/chest.123.4.1073\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12684296\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1378/chest.125.1.220\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/14718444\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/3743148\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/1729073\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/1545576\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.2307/2290630\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1097/00003246-200011000-00006\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11098960\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12734653\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1378/chest.125.2.597\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/14769744\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/14044222\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/1959406\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1097/00003246-199909000-00003\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10507588\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/5349366\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1378/chest.128.6.3937\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16354866\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1111/j.1530-0277.2000.tb02070.x\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10888079\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1016/j.jcrc.2004.11.003\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16015521\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1001/archinte.166.18.1993\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17030833\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1007/s001340050845\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10229171\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9187189\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1097/00005650-199206000-00002\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/1593914\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1007/s00134-005-2744-8\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16132895\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d5e29c7762eb32918b7c55cc80149692\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Organic + Papers\n\t\t\t\t 2-(4-Hydroxy\xADphen\xADyl)acetic + acid\u20134,4\u2032-bipyridine (1/1)\n\t\t\t\t 2010-05-26\n\t\t\t\t + \ International Union of Crystallography\n\t\t\t\t + \ eng\n\t\t\t\t In the acid + mol\xADecule of the title complex, C10H8N2\xB7C8H8O3, the acetyl C\u2014C\u2014C\u2014O + torsion angle is \u221232.1\u2005(3)\xB0, and in the mol\xADecule of the base, + the dihedral angle between the two pyridine rings is 23.41\u2005(10)\xB0. + In the crystal structure, inter\xADmolecular O\u2014H\u22EFN hydrogen bonds + link the acid and the base mol\xADecules into a one-dimensional triple-helix + framework extended along the b axis.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2979409\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.1107/S1600536810018842\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1979069\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t LIU, + JIAN-FENG\n\t\t\t\t Zhao, Guo-Liang\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC2979409\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d5edd881c6caf75e9f1f70ec3f423fb1\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Health + Services Research\n\t\t\t\t Early primary care physician + contact and health service utilisation in a large sample of recently released + ex-prisoners in Australia: prospective cohort study\n\t\t\t\t 2015-06-11\n\t\t\t\t + \ BMJ Publishing Group\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/doi/10.1136/bmjopen-2015-008021\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:3432394\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC4466622\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Lennox, + Nick\n\t\t\t\t Arnold-Reed, Diane\n\t\t\t\t + \ Bulsara, Max\n\t\t\t\t Kinner, + Stuart A\n\t\t\t\t Preen, David\n\t\t\t\t + \ Young, Jesse T\n\t\t\t\t info:eu-repo/grantAgreement///409966//PASSPORTS + TO ADVANTAGE: Health and capacity building as a basis for social integration/\n\t\t\t\t + \ info:eu-repo/grantAgreement///1078168//Monitoring and improving + the health of justice-involved populations: A public health priority/\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC4466622\n\t\t\t\t + \ http://europepmc.org/abstract/MED/26068513\n\t\t\t\t + \ http://dx.doi.org/10.1136/bmjopen-2015-008021\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21093904\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11297662\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:dedup_wf_001::038d3b96bdc5fa2b6b8659522bbfde86\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16020641\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12069208\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19648129\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19150898\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::ad7e4c88ae8e34320cc7488dbc8bb2ec\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21239522\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21632740\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19847638\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::8d674f30c2c0832236645f8410a23748\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/23877707\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21627727\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::2a688b3ebdabe4ba86409ed6df62f9a7\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19244192\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18048559\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/23711803\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15581440\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9702163\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::596d67eae6c4c2bda88f0c33c5db48ca\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15043376\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22762077\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20403022\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8725975\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9736872\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::86ab2ce8d086255fa84359a2996659b3\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16202000\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15635299\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15521163\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17223630\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22134521\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/23850859\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::4cf08203ded1b92454292ae389528962\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15230939\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12578436\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11824981\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/24690052\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:project_eucl::8012706d94331cb816ec793488969a48\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10985240\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/7981390\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::eb74c8888237d987eb91ce12cab05e6e\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19452569\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21225900\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/24938332\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21117913\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::6c8201cabadc023ab782f043071d1544\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21042930\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21915745\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16719762\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/22813476\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::0cd99d3786665e01fbe285dbe032ae76\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20579009\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d5f9d00bc77c9760b425fc4660a8fec8\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Primary + Care\n\t\t\t\t Reducing antibiotic use for acute + bronchitis in primary care: blinded, randomised controlled trial of patient + information leaflet\n\t\t\t\t 2002-01-12\n\t\t\t\t + \ BMJ Group\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC64506\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2014602\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Gard, + Philip\n\t\t\t\t Macfarlane, John\n\t\t\t\t + \ Hubbard, Richard\n\t\t\t\t Macfarlane, + Rosamund\n\t\t\t\t Holmes, William\n\t\t\t\t + \ Thornhill, David\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC64506\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d60ceb78ebe48037860fe3a0ee8fa3fe\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Abstracts\n\t\t\t\t + \ Equilibration and Exchange of Fluorescently Labeled Molecules + in Skeletal Muscle Fibers Studied Using Confocal Microscopy\n\t\t\t\t + \ 1995-04-01\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC1282010\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:323553\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Brenner, + B.\n\t\t\t\t Kraft, T\n\t\t\t\t Chalovich, + J. M.\n\t\t\t\t Rutishauser, B.\n\t\t\t\t + \ Messerli, M\n\t\t\t\t Perriard, + J.-C.\n\t\t\t\t Wallimann, T.\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC1282010\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d61ba4b71af96111e2f8fff65632d10b\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Fifth Pivotal Research in Cardiology in the Elderly (PRICE-V) + Symposium Preventive Cardiology in the Elderly\n\t\t\t\t 2009-01-01\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC2920485\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2005081\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t RICH, + MICHAEL W.\n\t\t\t\t Mensah, George A\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC2920485\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d63766d5a82f6ec5b0008dfa9e58ac17\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Letter + to the Editor\n\t\t\t\t An uncommon cause of vulval + pruritus in childhood: Lichen sclerosus\n\t\t\t\t 2014-03-01\n\t\t\t\t + \ Turkish Pediatrics Association\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC4462259\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.5152/tpa.2014.1365\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:3429806\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Say\u0131lgan, + Ay\u015Fe T\xFClay\n\t\t\t\t Topal, \u0130lteri\u015F + O\u011Fuz\n\t\t\t\t Kal\xE7\u0131n, Sibel\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC4462259\n\t\t\t\t + \ http://dx.doi.org/10.5152/tpa.2014.1365\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d63bae9c426510d1fba4d2a2bed3174e\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Original + Articles\n\t\t\t\t A Sketch of John Abernethy\n\t\t\t\t + \ 1904-04-01\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC1692193\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1101674\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Foster, + Burnside\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1692193\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d63d29f128beb2f0b002f0990b2afe89\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Original + Article\n\t\t\t\t Neuroendoscopic evacuation of + intraventricular hematoma associated with thalamic hemorrhage to shorten the + duration of external ventricular drainage\n\t\t\t\t 2010-08-10\n\t\t\t\t + \ Medknow Publications\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/doi/10.4103/2152-7806.68342\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC2940103\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1963606\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmid/20847924\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Nomura, + Sadahiro\n\t\t\t\t Shinoyama, Mizuya\n\t\t\t\t + \ Yoneda, Hiroshi\n\t\t\t\t Ishihara, + Hideyuki\n\t\t\t\t Shirao, Satoshi\n\t\t\t\t + \ Suzuki, Michiyasu\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2940103\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10920821\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15798667\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15926724\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19452411\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17905069\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15446586\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19300098\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/6182486\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15344894\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15335420\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/6977795\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19061146\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::dcd8e3583547695e8b994a3f4dc57ae2\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19246695\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8751626\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16051009\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/14968408\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2080366\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19763212\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16234662\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12182415\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19066112\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17468874\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16174973\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17948179\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19231066\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17553525\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17999899\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17405269\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18976083\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17084196\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15335426\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/2894232\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19348801\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:dedup_wf_001::124433b3c28c40b00597310f47a6d94e\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17204141\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17519550\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d6422242b8143319871d22165fcf5f95\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Original + Articles\n\t\t\t\t Immediate postoperative inflammatory + response predicts long-term outcome in lung-transplant recipients\u2020\n\t\t\t\t + \ 2012-07-19\n\t\t\t\t Oxford University + Press\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3445394\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2777589\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Hall, + David J\n\t\t\t\t Baz, Maher\n\t\t\t\t + \ Moldawer, Lyle L.\n\t\t\t\t Staples, + Edward Denmark\n\t\t\t\t Beaver, Thomas M.\n\t\t\t\t + \ Klodell, Charles T.\n\t\t\t\t Daniels, + Michael J\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3445394\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d65047578b523118342806202aae3be9\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Tribolium Wnts: evidence for a larger repertoire in insects + with overlapping expression patterns that suggest multiple redundant functions + in embryogenesis\n\t\t\t\t 2008-04-01\n\t\t\t\t + \ eng\n\t\t\t\t wingless (wg)/Wnt + family genes encode secreted glycoproteins that function as signaling molecules + in the development of vertebrates as well as invertebrates. In a survey of + Wnt family genes in the newly sequenced Tribolium genome, we found a total + of nine Wnt genes. In addition to wg or Wnt1, Tribolium contains orthologs + of the vertebrate Wnt5\u20137 and 9\u201311 genes. As in Drosophila, Wnt1, + 6 and 10 are clustered in the genome. Comparative genomics indicates that + Wnt9 is also a conserved member of this cluster in several insects for which + genome sequence is available. One of the Tribolium Wnt genes appears to be + a member of the WntA family, members of which have been identified in Anopheles + and other invertebrates, but not in Drosophila or vertebrates. Careful phylogenetic + examination suggests an Apis Wnt gene, previously identified as a Wnt4 homolog, + is also a member of the WntA family. The ninth Tribolium Wnt gene is related + to the diverged Drosophila WntD gene, both of which phylogenetically group + with Wnt8 genes. Some of the Tribolium Wnt genes display multiple overlapping + expression patterns, suggesting that they may be functionally redundant in + segmentation, brain, appendage and hindgut development. In contrast, the unique + expression patterns of Wnt5, Wnt7 and Wnt11 in developing appendages likely + indicate novel functions.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3206738\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2210132\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Beermann, + Anke\n\t\t\t\t Brown, Susan J.\n\t\t\t\t + \ Lutz, Rebekka\n\t\t\t\t Wittkopp, + Nadine\n\t\t\t\t Bolognesi, Renata\n\t\t\t\t + \ Farzana, Laila\n\t\t\t\t Balavoine, + Guillaume\n\t\t\t\t Schr\xF6der, Reinhard\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC3206738\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d65297ab5ba729cd473a3ff63dbb022e\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Medical + Practice\n\t\t\t\t Personal View\n\t\t\t\t + \ 1988-06-18\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC2546106\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1175978\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2546106\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d65c02609485f19afda91fca30b138ac\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Drug-resistant pulmonary tuberculosis + in the Baja California-San Diego County border population.\n\t\t\t\t + \ 1998-10-01\n\t\t\t\t eng\n\t\t\t\t + \ A study was conducted to determine the frequency of, and + risk factors for, drug-resistant pulmonary tuberculosis (TB) among Baja California + (BC) and San Diego County (SDC) residents. Another purpose was to document + the amount of contact between pulmonary TB patients and residents of the opposite + side of the the border. During the period from February 1995 to May 1996, + pulmonary TB patients from BC (n = 427) and SDC (n = 331) were evaluated with + cultures, drug susceptibility tests, and questionnaires. Drug resistance was + found in 41% of the BC Mycobacterium tuberculosis complex (MTB) isolates and + 20% of the SDC isolates. Resistance to both isoniazid (INH) and rifampin (RIF) + varied from 1% of isolates from SDC patients to 17% of isolates from BC patients. + Patients with a history of previous treatment had increased odds of drug-resistant + disease. Older BC patients were more likely to have INH- or RIF-resistant + TB. Although 42% of Tijuana TB patients reported recent contact with residents + from SDC, travel to Mexico and contact with residents from Mexico were not + significant risk factors for drug-resistant TB among SDC residents. However, + the demonstrated contact between TB patients and residents on opposite sides + of the border indicates the importance of coordinating efforts internationally + to control TB.\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC1305288\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:268640\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Freeman, + R\n\t\t\t\t COX, M\n\t\t\t\t Lomeli, + M R\n\t\t\t\t Ramirez-Zetina, M\n\t\t\t\t + \ Moser, K.\n\t\t\t\t Schultz, E.\n\t\t\t\t + \ Peter, C R\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1305288\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d65eb5976df8ce24d7e059c4d009674c\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Clinical, electrocardiographic, + and haemodynamic effects of long-term use of propranolol in Prinzmetal's variant + angina pectoris.\n\t\t\t\t 1971-11-01\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC458444\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:717478\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t F. + Magrini\n\t\t\t\t Guazzi, M.\n\t\t\t\t + \ Fiorentini, C\n\t\t\t\t Polese, + A.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC458444\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d6663f94a72f643df4ae65ff7cbfdd45\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Article\n\t\t\t\t + \ Mutational Effect of Fission Yeast Pol\u03B1 on Cell Cycle Events\n\t\t\t\t + \ 1998-08-01\n\t\t\t\t The American + Society for Cell Biology\n\t\t\t\t eng\n\t\t\t\t + \ Pol\u03B1 is the principal DNA polymerase for initiation + of DNA replication and also functions in postinitiation DNA synthesis. In + this study, we investigated the cell cycle responses induced by mutations + in pol\u03B1+. Germinating spores carrying either a deletion of pol\u03B1+ + (pol\u03B1\u0394) or a structurally intact but catalytically dead pol\u03B1 + mutation proceed to inappropriate mitosis with no DNA synthesis. This suggests + that the catalytic function, and not the physical presence of Pol\u03B1, is + required to generate the signal that prevents the cells from entering mitosis + prematurely. Cells with a pol\u03B1ts allele arrest the cell cycle near the + hydroxyurea arrest point, but, surprisingly, pol\u03B1ts in cdc20 (pol\u03B5 + mutant) background arrested with a cdc phenoytpe, not a pol\u03B1ts-like phenotype. + At 25\xB0C, replication perturbation caused by pol\u03B1ts alleles induces + Cds1 kinase activity and requires the checkpoint Rads, Cds1, and Rqh1, but + not Chk1, to maintain cell viability. At 36\xB0C, replication disruption caused + by pol\u03B1ts alleles induces the phosphorylation of Chk1; however, mutant + cells arrest with heterogeneous cell sizes with a population of the cells + entering aberrant mitosis. Together, our results indicate that the initiation + DNA structure synthesized by Pol\u03B1 is required to bring about the S phase + to mitosis checkpoint, whereas replication defects of different severity caused + by pol\u03B1ts mutations induce differential downstream kinase responses.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC25465\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1799569\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Bhaumik, + Dipa\n\t\t\t\t Wang, Teresa S.-F.\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC25465\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d667b2e3f35d9c87703cc1789a91d1d4\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Letters\n\t\t\t\t + \ Dr. Norman responds\n\t\t\t\t 1992-06-01\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC1490363\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:299811\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Norman, + Richard W.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1490363\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d675599a4479b79267035fa21bd2df0d\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ THE FREEZING POINT DEPRESSION OF MAMMALIAN TISSUES IN RELATION + TO THE QUESTION OF OSMOTIC ACTIVITY OF CELL FLUID\n\t\t\t\t 1956-11-20\n\t\t\t\t + \ The Rockefeller University Press\n\t\t\t\t + \ eng\n\t\t\t\t The freezing + point depression of freshly excised frozen tissues, pulverized in a hydraulic + press or in a mortar, is greater than that of plasma. Even at 0\xB0C. the + freezing point depression of such homogenates increases significantly with + time. Dilution data indicate that such freezing point data are valid. The + presence of intact cells has been shown in smears of tissues pulverized in + a mortar, but not in smears of those crushed in a hydraulic press. The osmolarity + of various diluent solutions affects the calculated osmotic activity of tissue + homogenates presumably because of delayed diffusion between the diluent and + cell fluid. With a hypertonic NaCl diluent, spuriously low values of tissue + osmotic activity are found from calculations assuming instantaneous mixing + between homogenates and diluents. The limitations of data from cryoscopic + experiments and from tissue-swelling experiments are discussed in relation + to the basic question of whether or not cell fluid is isotonic to extracellular + fluid.\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC2147618\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmid/13385447\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1574746\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Dennis, + Warren H.\n\t\t\t\t Miley, John F.\n\t\t\t\t + \ Brodsky, William A.\n\t\t\t\t Rehm, + Warren S.\n\t\t\t\t Diamond, Israel\n\t\t\t\t + \ Appelboom, Johannes W.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2147618\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d677a6fc50958c1fb99660526a5af1a0\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Book + Reviews\n\t\t\t\t Lumbar Spine and Back Pain\n\t\t\t\t + \ 1987-11-01\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC1003414\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:399241\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Sweetman, + B. J.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1003414\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d65d6230469be3b3ec5ffda4078a354a\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Paper\n\t\t\t\t Identification of Pluripotency Genes + in the Fish Medaka\n\t\t\t\t 2011-04-15\n\t\t\t\t + \ Ivyspring International Publisher\n\t\t\t\t + \ eng\n\t\t\t\t Stem cell + cultures can be derived directly from early developing embryos and indirectly + from differentiated cells by forced expression of pluripotency transcription + factors. Pluripotency genes are routinely used to characterize mammalian stem + cell cultures at the molecular level. However, such genes have remained unknown + in lower vertebrates. In this regard, the laboratory fish medaka is uniquely + suited because it has embryonic stem (ES) cells and genome sequence data. + We identified seven medaka pluripotency genes by homology search and expression + in vivo and in vitro. By RT-PCR analysis, the seven genes fall into three + groups of expression pattern. Group I includes nanog and oct4 showing gonad-specific + expression; Group II contains sall4 and zfp281 displaying gonad-preferential + expression; Group III has klf4, ronin and tcf3 exhibiting expression also + in several somatic tissues apart from the gonads. The transcripts of the seven + genes are maternally supplied and persist at a high level during early embryogenesis. + We made use of early embryos and adult gonads to examine expression in stem + cells and differentiated derivatives by in situ hybridization. Strikingly, + nanog and oct4 are highly expressed in pluripotent blastomeres of 16-cell + embryos. In the adult testis, nanog expression was specific to spermatogonia, + the germ stem cells, whereas tcf3 expression occurred in spermatogonia and + differentiated cells. Most importantly, all the seven genes are pluripotency + markers in vitro, because they have high expression in undifferentiated ES + cells but dramatic down-regulation upon differentiation. Therefore, these + genes have conserved their pluripotency-specific expression in vitro from + mammals to lower vertebrates.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3088286\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2099016\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Hong, + Yunhan\n\t\t\t\t Yan, Yan\n\t\t\t\t + \ Wang, Li\n\t\t\t\t Wang, Danke\n\t\t\t\t + \ Hong, Ni\n\t\t\t\t Li, Zhendong\n\t\t\t\t + \ Wang, Tiansu\n\t\t\t\t Manali, + Dwarakanath\n\t\t\t\t Bhat, Narayani\n\t\t\t\t + \ Liu, Rong\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3088286\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12609601\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9831563\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11576176\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12514105\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16153702\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11861474\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19544407\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12787492\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______463::5fc9eaaf27c22468e8ef9e04dea07b10\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12787505\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18347094\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::c38255c67e85ae5a25a0c641a630ab72\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18585351\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12642497\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18983969\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/7242681\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16565704\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20238480\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::eea223631dbb2a68b672419d044a5a22\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15141090\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15210197\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9025059\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9520425\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15210170\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11057671\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19249358\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::e291c0bd36209561db4e70a23bdfc740\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18804426\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19577665\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16518401\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/14711414\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::f21989d663e121bb67ddbcab82bfd5c8\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::346b0a8a0b07395f1d744d57b8f31551\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11226261\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/6950406\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19184566\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10742100\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18199879\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9819561\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9507072\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::8834cb0e66713ddf277e8890efbce702\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20034054\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::9bcdca831b48598c8d708f6d9f8a270c\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16904174\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18467660\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/9804556\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19476507\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18757296\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16166252\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11823791\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15788707\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19564913\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20671725\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19833967\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20596908\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d65f96202058321d4af70140eb8fe9ee\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Proprioceptive modulation of somatosensory + evoked potentials during active or passive finger movements in man.\n\t\t\t\t + \ 1981-10-01\n\t\t\t\t eng\n\t\t\t\t + \ The effects of active and passive finger movements on + somatosensory potentials evoked by stimulation of the median nerve at the + wrist or of finger I were investigated in 15 healthy volunteers. As compared + to the resting condition, both active and passive movements of the stimulated + hand fingers induced a marked reduction in the amplitude of the primary cerebral + response (N20-P25 complex) as well as of the N17 SEP component, which is supposed + to reflect the activity of the thalamo-cortical radiation. The following cerebral + SEP components, within 100 ms after the stimulus, were also depressed during + motor activity. Neither N11 nor N13 components of the cervical response, reflecting + the activation of dorsal columns and dorsal column nuclei respectively, were + modified. The SEP changes induced by active or passive movements were absent + after ischaemic block of large group I afferent fibers from the hand, thus + suggesting the relevance of the feedback generated by such peripheral afferents + during movement. The results indicate that the activation of peripheral receptors + (probably muscle spindle endings) during both active and passive finger movement + would induce a gating effect at both cortical and subcortical (thalamic) level, + which might modulate selectively the different sensory inputs to the cortex.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC491182\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:1473682\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Abbruzzese, + M.\n\t\t\t\t Favale, E\n\t\t\t\t + \ Ratto, S\n\t\t\t\t Abbruzzese, + G.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC491182\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d67f39479622684ccca2c27f7cd97710\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Editorial\n\t\t\t\t + \ Controlling antimicrobial resistance: Interfering in the process + of natural selection\n\t\t\t\t 2013-11-18\n\t\t\t\t + \ BioMed Central\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmid/24237889\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2821605\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.1186/2047-2994-2-32\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC3835547\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Mouton, + Johan W.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3835547\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:dedup_wf_001::60fa3f5059be47d2c0bee82fb9f18a57\n\t\t\t\t + \ info:eu-repo/semantics/reference/doi/10.1186/2047-2994-2-31\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d68215698b7e358346e9d1f97f5d9a47\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Correspondence\n\t\t\t\t + \ National Health Service\n\t\t\t\t 1947-01-11\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC2052329\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:583538\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Harris, + I.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2052329\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d68458c02846fd81053f10e16df5f635\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Nonparametric Bayes Conditional Distribution Modeling With Variable + Selection\n\t\t\t\t 2009-12-01\n\t\t\t\t + \ eng\n\t\t\t\t This article + considers a methodology for flexibly characterizing the relationship between + a response and multiple predictors. Goals are (1) to estimate the conditional + response distribution addressing the distributional changes across the predictor + space, and (2) to identify important predictors for the response distribution + change both within local regions and globally. We first introduce the probit + stick-breaking process (PSBP) as a prior for an uncountable collection of + predictor-dependent random distributions and propose a PSBP mixture (PSBPM) + of normal regressions for modeling the conditional distributions. A global + variable selection structure is incorporated to discard unimportant predictors, + while allowing estimation of posterior inclusion probabilities. Local variable + selection is conducted relying on the conditional distribution estimates at + different predictor points. An efficient stochastic search sampling algorithm + is proposed for posterior computation. The methods are illustrated through + simulation and applied to an epidemiologic study.\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3620660\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2621202\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Chung, + Yeonseung\n\t\t\t\t Dunson, David B.\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC3620660\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d6853226f7cb614d710af6dbd8b285a5\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Olanzapine Augmentation of Fluoxetine in Body Dysmorphic Disorder\n\t\t\t\t + \ 2005-05-01\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC1613796\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:692649\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Phillips, + Katharine A.\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC1613796\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d68690e60843c1d93e5ccaf2856cf061\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Ethics of the social determinants of health\n\t\t\t\t + \ 2004-09-18\n\t\t\t\t eng\n\t\t\t\t + \ Europe PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/pmc/PMC3988689\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2968118\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t RUGER, + JENNIFER PRAH\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3988689\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d697412c30ba435f1944fb9ba10130df\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\n\t + \ \n\t \n\t\t\t\t \n\t\t\t\t Articles\n\t\t\t\t + \ DEPENDENCE OF THE FORM OF THE ELECTRO-CARDIOGRAM UPON THE SITE + OF MECHANICAL STIMULATION OF THE HUMAN VENTRICLES\n\t\t\t\t 1927-02-01\n\t\t\t\t + \ eng\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC434648\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:761023\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Oppenheimer, + B. S.\n\t\t\t\t Stewart, Harold J.\n\t\t\t\t + \ info:eu-repo/semantics/article\n\t\t\t\t http://europepmc.org/articles/PMC434648\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d69d416a54b7a1ad38d8dcfb281f5537\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Articles\n\t\t\t\t + \ Determination of 4-Methylimidazole and 2-Acetyl-4(5)- tetrahydroxybutylimidazole + in Caramel Color and Processed Foods by LC-MS/MS\n\t\t\t\t 2013-12-01\n\t\t\t\t + \ The Korean Society of Food Science and Nutrition\n\t\t\t\t + \ eng\n\t\t\t\t In this study, + the quick HPLC-MS/MS method for the simultaneous separation of 2-acetyl-4(5)-tetrahydrox-ybuthylimidazole + (THI) and 4-(5)-methylimidazole (4-MI) in alkaline medium was used for caramel + color and processed foods in Korea. After a simple sample pretreatment, 51 + 4-MI-labeled samples were positive for 4-MI and 2 also contained THI. The + concentration of 4-MI was 260.5 ~ 24,499.3 \u03BCg/kg in caramel color, less + than LOD ~ 1,712.5 \u03BCg/kg in sauce, 1,242.3, 5,972.2 \u03BCg/kg in balsamic + vinegar, 2,118.3 ~ 5,802.4 \u03BCg/kg in complex seasoning, 82.7 ~ 5,110.6 + \u03BCg/kg in curry, and 29.9 ~ 464.4 \u03BCg/kg in soft drinks. The recovery + rate of 4-MI was 97.1 ~ 111.0% in sauce and 81.9 ~ 110.0% in powder and that + of THI was 83.6 ~ 106.4% in sauce and 61.2 ~ 99.4% in powder. Our results + concluded a safe amount of 4-MI and THI compared to the limit of Korea additive + code but the processed foods do not have a limit of caramel color and 4-MI + in Korea. Therefore, research and monitoring of 4-MI and THI is needed for + processed foods in Korea.\n\t\t\t\t Europe + PubMed Central\n\t\t\t\t info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2910191\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.3746/pnf.2013.18.4.263\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC3925216\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Lee, + Sang Me\n\t\t\t\t Shin, Young\n\t\t\t\t + \ Kim, Ji Young\n\t\t\t\t Kim, Jung + Hun\n\t\t\t\t Kim, Tae Rang\n\t\t\t\t + \ Kim, Su Un\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3925216\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12462620\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16180012\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17619857\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:dedup_wf_001::20428ac955b217e165d5e0941b684b29\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16544879\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:dedup_wf_001::20428ac955b217e165d5e0941b684b29\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16982517\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/1644383\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21879707\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\t\n\t\t\t\n\t\t\t\toai:dnet:od_______908::d6a614ae5721a6bb83c960e2b83a5367\n\t\t\t\t\t\t2015-09-12T20:33:44Z\n\t + \ \t\t\tEurope_PubMed_Central\n\t \t\t\t\t\t\tEurope_PubMed_Central_enriched\n\t + \ \t\t\t\n\t \n\t \n\t\t\t\t + \n\t\t\t\t Article\n\t\t\t\t + \ Visualizing the transfer-messenger RNA as the ribosome resumes + translation\n\t\t\t\t 2010-10-12\n\t\t\t\t + \ Nature Publishing Group\n\t\t\t\t eng\n\t\t\t\t + \ Bacterial ribosomes that are stalled on mRNAs lacking + a stop codon can be rescued by a process called \u2018transtranslation' that + involves the ribonucleoprotein complex tmRNA\u2013SmpB. This cryo-EM study, + and the copublished study by Weis et al, reveal how translation on tmRNA is + resumed\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmid/20940705\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2022032\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.1038/emboj.2010.255\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC2989109\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Wower, + Iwona\n\t\t\t\t Zwieb, Christian\n\t\t\t\t + \ Frank, Joachim\n\t\t\t\t Liao, + Hstau Y\n\t\t\t\t WOWER, JACEK\n\t\t\t\t + \ Hashem, Yaser\n\t\t\t\t Lei, Jianlin\n\t\t\t\t + \ Fu, Jie\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC2989109\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::84378b3875cf7fe03e1c1c2bdfcdc375\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17488812\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:dedup_wf_001::12772410c8ab599c8b9dad92fa69d9f9\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18396159\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19883769\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12809609\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::c3896945863dfbe4fbcf79bf6abd27f1\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18079724\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______166::bcd456e5d621e1be226f9fe47be6e045\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12904796\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11904181\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::ea6409ae366940ef1ae9ed1609ae18d9\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17400816\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15967466\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::f384a28a6c23ac03764eed579f501e5b\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20562414\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15905274\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::46dc882ae0b9c726354fa6dc48e109c3\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17056712\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8584937\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/8584937\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::8abde62f6084af089f8fae8c88db0832\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17698641\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::1336ecbf54dfee9e8beba905a08d05aa\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18606549\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::c49681bce937a136d33c6ce7122b63a8\n\t\t\t\t + \ 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info:eu-repo/semantics/reference/openaire/oai:dnet:dedup_wf_001::61bcf39ec9791237c1dd12bf59c27090\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10445873\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17179934\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16272117\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19180078\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::9159d2a5dad6ab3e22c90d6421410e3a\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18462672\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::a7f94edda0f2b67cd26715b54287fc8f\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15100436\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/7536743\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12677067\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::f73f9bc79ca1bd297daede1d3568b5b3\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12853578\n\t\t\t\t + \ 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\n\t \n\t\t\t\t + \n\t\t\t\t Research + Article\n\t\t\t\t Role of Transposon-Derived Small + RNAs in the Interplay between Genomes and Parasitic DNA in Rice\n\t\t\t\t + \ 2012-09-01\n\t\t\t\t Public Library + of Science\n\t\t\t\t eng\n\t\t\t\t + \ RNA silencing is a defense system against \u201Cgenomic + parasites\u201D such as transposable elements (TE), which are potentially + harmful to host genomes. In plants, transcripts from TEs induce production + of double-stranded RNAs (dsRNAs) and are processed into small RNAs (small + interfering RNAs, siRNAs) that suppress TEs by RNA\u2013directed DNA methylation. + Thus, the majority of TEs are epigenetically silenced. On the other hand, + most of the eukaryotic genome is composed of TEs and their remnants, suggesting + that TEs have evolved countermeasures against host-mediated silencing. Under + some circumstances, TEs can become active and increase in copy number. Knowledge + is accumulating on the mechanisms of TE silencing by the host; however, the + mechanisms by which TEs counteract silencing are poorly understood. Here, + we show that a class of TEs in rice produces a microRNA (miRNA) to suppress + host silencing. Members of the microRNA820 (miR820) gene family are located + within CACTA DNA transposons in rice and target a de novo DNA methyltransferase + gene, OsDRM2, one of the components of epigenetic silencing. We confirmed + that miR820 negatively regulates the expression of OsDRM2. In addition, we + found that expression levels of various TEs are increased quite sensitively + in response to decreased OsDRM2 expression and DNA methylation at TE loci. + Furthermore, we found that the nucleotide sequence of miR820 and its recognition + site within the target gene in some Oryza species have co-evolved to maintain + their base-pairing ability. The co-evolution of these sequences provides evidence + for the functionality of this regulation. Our results demonstrate how parasitic + elements in the genome escape the host's defense machinery. Furthermore, our + analysis of the regulation of OsDRM2 by miR820 sheds light on the action of + transposon-derived small RNAs, not only as a defense mechanism for host genomes + but also as a regulator of interactions between hosts and their parasitic + elements.\n\t\t\t\t Europe PubMed Central\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/pmc/PMC3459959\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/oai/oai:europepmc.org:2458817\n\t\t\t\t + \ info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pgen.1002953\n\t\t\t\t + \ info:eu-repo/semantics/openAccess\n\t\t\t\t Sato, + Yutaka\n\t\t\t\t Itoh, Jun-ichi\n\t\t\t\t + \ Ono, Akemi\n\t\t\t\t Nosaka, Misuzu\n\t\t\t\t + \ Nagato, Yasuo\n\t\t\t\t Ishiwata, + Aiko\n\t\t\t\t info:eu-repo/semantics/article\n\t\t\t\t + \ http://europepmc.org/articles/PMC3459959\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12016302\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15866029\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17975059\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21074719\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::9c0547d0f69ac85104a003e69e5d84cf\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15575975\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19007329\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19243928\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11988759\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12188048\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19074682\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19239888\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::14abb11caa403fe28654c3ac1f5600d5\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20621980\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20381393\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::8e68d5301c19bdc945248b5a9c276225\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/18089549\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16959252\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10781108\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/12121623\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19788421\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/21060858\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/20805329\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16111943\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15705854\n\t\t\t\t + \ info:eu-repo/semantics/reference/openaire/oai:dnet:od_______908::11c44f842d15cb12c53d95accec96020\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/16449203\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/10588717\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/11459066\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/17339227\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/19734880\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/7920717\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/15851028\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/3447015\n\t\t\t\t + \ info:eu-repo/semantics/reference/pmid/7683079\n\t\t\t\t + \n\t\t\t\t\n\t\t\t\t\n\t\t\t\n\t\t\n\t\n\t-1|oai_dc|oaftype="result" AND datestamp >= + 2015-09-12T00:00:00Z AND datestamp <= 2015-09-14T00:00:00Z|100|55f48c42422f023b2d11b214|true|\n"} + headers: + cache-control: [max-age=2592000] + connection: [keep-alive] + content-language: [en-US] + content-type: [text/xml;charset=utf-8] + date: ['Mon, 14 Sep 2015 22:30:46 GMT'] + expires: ['Wed, 14 Oct 2015 22:30:46 GMT'] + server: [nginx] + status: {code: 200, message: OK} +version: 1