diff --git a/chebai/preprocessing/bin/protein_token_3_gram/tokens.txt b/chebai/preprocessing/bin/protein_token_3_gram/tokens.txt
new file mode 100644
index 00000000..69dca126
--- /dev/null
+++ b/chebai/preprocessing/bin/protein_token_3_gram/tokens.txt
@@ -0,0 +1,8000 @@
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diff --git a/chebai/preprocessing/datasets/go_uniprot.py b/chebai/preprocessing/datasets/go_uniprot.py
index dba9940e..a2c4ae54 100644
--- a/chebai/preprocessing/datasets/go_uniprot.py
+++ b/chebai/preprocessing/datasets/go_uniprot.py
@@ -8,9 +8,15 @@
 # https://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/complete/docs/keywlist.txt
 # https://www.uniprot.org/uniprotkb
 
-__all__ = ["GOUniProtOver250", "GOUniProtOver50"]
+__all__ = [
+    "GOUniProtOver250",
+    "GOUniProtOver50",
+    "EXPERIMENTAL_EVIDENCE_CODES",
+    "AMBIGUOUS_AMINO_ACIDS",
+]
 
 import gzip
+import itertools
 import os
 import shutil
 from abc import ABC, abstractmethod
@@ -24,11 +30,24 @@
 import requests
 import torch
 from Bio import SwissProt
-from torch.utils.data import DataLoader
 
 from chebai.preprocessing import reader as dr
 from chebai.preprocessing.datasets.base import _DynamicDataset
 
+EXPERIMENTAL_EVIDENCE_CODES = {
+    "EXP",
+    "IDA",
+    "IPI",
+    "IMP",
+    "IGI",
+    "IEP",
+    "TAS",
+    "IC",
+}
+
+# https://github.com/bio-ontology-research-group/deepgo/blob/d97447a05c108127fee97982fd2c57929b2cf7eb/aaindex.py#L8
+AMBIGUOUS_AMINO_ACIDS = {"B", "O", "J", "U", "X", "Z", "*"}
+
 
 class _GOUniProtDataExtractor(_DynamicDataset, ABC):
     """
@@ -73,13 +92,20 @@ class _GOUniProtDataExtractor(_DynamicDataset, ABC):
 
     def __init__(self, **kwargs):
         self.go_branch: str = self._get_go_branch(**kwargs)
-        super(_GOUniProtDataExtractor, self).__init__(**kwargs)
 
         self.max_sequence_length: int = int(kwargs.get("max_sequence_length", 1002))
         assert (
             self.max_sequence_length >= 1
         ), "Max sequence length should be greater than or equal to 1."
 
+        super(_GOUniProtDataExtractor, self).__init__(**kwargs)
+
+        if self.reader.n_gram is not None:
+            assert self.max_sequence_length >= self.reader.n_gram, (
+                f"max_sequence_length ({self.max_sequence_length}) must be greater than "
+                f"or equal to n_gram ({self.reader.n_gram})."
+            )
+
     @classmethod
     def _get_go_branch(cls, **kwargs) -> str:
         """
@@ -333,7 +359,20 @@ def _graph_to_raw_dataset(self, g: nx.DiGraph) -> pd.DataFrame:
         print(f"Processing graph")
 
         data_df = self._get_swiss_to_go_mapping()
-
+        # add ancestors to go ids
+        data_df["go_ids"] = data_df["go_ids"].apply(
+            lambda go_ids: sorted(
+                set(
+                    itertools.chain.from_iterable(
+                        [
+                            [go_id] + list(g.predecessors(go_id))
+                            for go_id in go_ids
+                            if go_id in g.nodes
+                        ]
+                    )
+                )
+            )
+        )
         # Initialize the GO term labels/columns to False
         selected_classes = self.select_classes(g, data_df=data_df)
         new_label_columns = pd.DataFrame(
@@ -391,26 +430,13 @@ def _get_swiss_to_go_mapping(self) -> pd.DataFrame:
             )
         )
 
-        EXPERIMENTAL_EVIDENCE_CODES = {
-            "EXP",
-            "IDA",
-            "IPI",
-            "IMP",
-            "IGI",
-            "IEP",
-            "TAS",
-            "IC",
-        }
-        # https://github.com/bio-ontology-research-group/deepgo/blob/d97447a05c108127fee97982fd2c57929b2cf7eb/aaindex.py#L8
-        AMBIGUOUS_AMINO_ACIDS = {"B", "O", "J", "U", "X", "Z", "*"}
-
         for record in swiss_data:
             if record.data_class != "Reviewed":
                 # To consider only manually-annotated swiss data
                 continue
 
-            if not record.sequence:
-                # Consider protein with only sequence representation
+            if not record.sequence or len(record.sequence) > self.max_sequence_length:
+                # Consider protein with only sequence representation and seq. length not greater than max seq. length
                 continue
 
             if any(aa in AMBIGUOUS_AMINO_ACIDS for aa in record.sequence):
@@ -531,29 +557,6 @@ def _get_data_splits(self) -> Tuple[pd.DataFrame, pd.DataFrame, pd.DataFrame]:
 
         return df_train, df_val, df_test
 
-    # ------------------------------ Phase: DataLoaders -----------------------------------
-    def dataloader(self, kind: str, **kwargs) -> DataLoader:
-        """
-        Returns a DataLoader object with truncated sequences for the specified kind of data (train, val, or test).
-
-        This method overrides the dataloader method from the superclass. After fetching the dataset from the
-        superclass, it truncates the 'features' of each data instance to a maximum length specified by
-        `self.max_sequence_length`.
-
-        Args:
-            kind (str): The kind of data to load (e.g., 'train', 'val', 'test').
-            **kwargs: Additional keyword arguments passed to the superclass dataloader method.
-
-        Returns:
-            DataLoader: A DataLoader object with the truncated sequences.
-        """
-        dataloader = super().dataloader(kind, **kwargs)
-
-        # Truncate the 'features' to max_sequence_length for each instance
-        for instance in dataloader.dataset:
-            instance["features"] = instance["features"][: self.max_sequence_length]
-        return dataloader
-
     # ------------------------------ Phase: Raw Properties -----------------------------------
     @property
     def base_dir(self) -> str:
@@ -565,16 +568,6 @@ def base_dir(self) -> str:
         """
         return os.path.join("data", f"GO_UniProt")
 
-    @property
-    def identifier(self) -> tuple:
-        """Identifier for the dataset."""
-        # overriding identifier instead of reader.name to keep same tokens.txt file, but different processed_dir folder
-        if not isinstance(self.reader, dr.ProteinDataReader):
-            raise ValueError("Need Protein DataReader for identifier")
-        if self.reader.n_gram is not None:
-            return (f"{self.reader.name()}_{self.reader.n_gram}_gram",)
-        return (self.reader.name(),)
-
     @property
     def raw_file_names_dict(self) -> dict:
         """
@@ -611,13 +604,16 @@ def _name(self) -> str:
         """
         Returns the name of the dataset.
 
+        'max_sequence_length' in the name indicates that proteins with sequence lengths exceeding  are ignored
+        in the dataset.
+
         Returns:
             str: The dataset name, formatted with the current threshold value and/or given go_branch.
         """
         if self.go_branch != self._ALL_GO_BRANCHES:
-            return f"GO{self.THRESHOLD}_{self.go_branch}"
+            return f"GO{self.THRESHOLD}_{self.go_branch}_{self.max_sequence_length}"
 
-        return f"GO{self.THRESHOLD}"
+        return f"GO{self.THRESHOLD}_{self.max_sequence_length}"
 
     def select_classes(
         self, g: nx.DiGraph, *args: Any, **kwargs: Dict[str, Any]
@@ -665,20 +661,8 @@ def select_classes(
         # https://github.com/bio-ontology-research-group/deepgo/blob/master/get_functions.py#L59-L77
         go_term_annot: Dict[int, int] = {}
         for idx, row in data_df.iterrows():
-            # Set will contain go terms associated with the protein, along with all the ancestors of those
-            # associated go terms
-            associated_go_ids_with_ancestors = set()
-
-            # Collect all ancestors of the GO terms associated with this protein
-            for go_id in row["go_ids"]:
-                if go_id in g.nodes:
-                    associated_go_ids_with_ancestors.add(go_id)
-                    associated_go_ids_with_ancestors.update(
-                        g.predecessors(go_id)
-                    )  # Add all predecessors (ancestors) of go_id
-
             # Count the annotations for each go_id **`per protein`**
-            for go_id in associated_go_ids_with_ancestors:
+            for go_id in row["go_ids"]:
                 if go_id not in go_term_annot:
                     go_term_annot[go_id] = 0
                 go_term_annot[go_id] += 1
diff --git a/chebai/preprocessing/datasets/protein_pretraining.py b/chebai/preprocessing/datasets/protein_pretraining.py
new file mode 100644
index 00000000..8550db2b
--- /dev/null
+++ b/chebai/preprocessing/datasets/protein_pretraining.py
@@ -0,0 +1,279 @@
+__all__ = ["SwissProteinPretrain"]
+
+import os
+from abc import ABC
+from collections import OrderedDict
+from typing import Any, Dict, Generator, List, Tuple
+
+import networkx as nx
+import pandas as pd
+import torch
+from Bio import SwissProt
+from sklearn.model_selection import train_test_split
+
+from chebai.preprocessing.datasets.base import _DynamicDataset
+from chebai.preprocessing.datasets.go_uniprot import (
+    AMBIGUOUS_AMINO_ACIDS,
+    EXPERIMENTAL_EVIDENCE_CODES,
+    GOUniProtOver250,
+)
+from chebai.preprocessing.reader import ProteinDataReader
+
+
+class _ProteinPretrainingData(_DynamicDataset, ABC):
+    """
+    Data module for pretraining protein sequences, specifically designed for Swiss-UniProt data. It includes methods for
+    data preparation, loading, and dynamic splitting of protein sequences.
+    The data is parsed and filtered to only select proteins with no associated `valid` Gene Ontology (GO) labels.
+    A valid GO label is the one which has one of evidence codes defined in `EXPERIMENTAL_EVIDENCE_CODES`.
+    """
+
+    _ID_IDX: int = 0
+    _DATA_REPRESENTATION_IDX: int = 1  # Index of `sequence` column
+
+    def __init__(self, **kwargs):
+        """
+        Initializes the data module with any GOUniProt extractor class object.
+
+        Args:
+            **kwargs: Additional arguments for the superclass initialization.
+        """
+        self._go_uniprot_extractor = GOUniProtOver250()
+        assert self._go_uniprot_extractor.go_branch == GOUniProtOver250._ALL_GO_BRANCHES
+
+        self.max_sequence_length: int = int(kwargs.get("max_sequence_length", 1002))
+        assert (
+            self.max_sequence_length >= 1
+        ), "Max sequence length should be greater than or equal to 1."
+
+        super(_ProteinPretrainingData, self).__init__(**kwargs)
+
+        if self.reader.n_gram is not None:
+            assert self.max_sequence_length >= self.reader.n_gram, (
+                f"max_sequence_length ({self.max_sequence_length}) must be greater than "
+                f"or equal to n_gram ({self.reader.n_gram})."
+            )
+
+    # ------------------------------ Phase: Prepare data -----------------------------------
+    def prepare_data(self, *args: Any, **kwargs: Any) -> None:
+        """
+        Prepares the data by downloading and parsing Swiss-Prot data if not already available. Saves the processed data
+        for further use.
+
+        Args:
+            *args: Additional positional arguments.
+            **kwargs: Additional keyword arguments.
+        """
+        processed_name = self.processed_dir_main_file_names_dict["data"]
+        if not os.path.isfile(os.path.join(self.processed_dir_main, processed_name)):
+            print("Missing processed data file (`data.pkl` file)")
+            os.makedirs(self.processed_dir_main, exist_ok=True)
+            self._download_required_data()
+            protein_df = self._parse_protein_data_for_pretraining()
+            self.save_processed(protein_df, processed_name)
+
+    def _extract_class_hierarchy(self, data_path: str) -> nx.DiGraph:
+        # method not required as no Swiss-UniProt has no ontological data
+        pass
+
+    def _graph_to_raw_dataset(self, graph: nx.DiGraph) -> pd.DataFrame:
+        # method not required as no Swiss-UniProt has no ontological data
+        pass
+
+    def select_classes(self, g: nx.DiGraph, *args, **kwargs) -> List:
+        # method not required as no Swiss-UniProt has no ontological data
+        pass
+
+    def _download_required_data(self) -> str:
+        """
+        Downloads the required Swiss-Prot data using the GOUniProt extractor class.
+
+        Returns:
+            str: Path to the downloaded data.
+        """
+        return self._go_uniprot_extractor._download_swiss_uni_prot_data()
+
+    def _parse_protein_data_for_pretraining(self) -> pd.DataFrame:
+        """
+        Parses the Swiss-Prot data and returns a DataFrame containing Swiss-Prot proteins which does not have any valid
+        Gene Ontology(GO) label. A valid GO label is the one which has one of the following evidence code
+        (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC).
+
+        The DataFrame includes the following columns:
+            - "swiss_id": The unique identifier for each Swiss-Prot record.
+            - "sequence": The protein sequence.
+
+        Note:
+            We ignore proteins with ambiguous amino acid codes (B, O, J, U, X, Z) in their sequence.`
+
+        Returns:
+            pd.DataFrame: A DataFrame where each row corresponds to a Swiss-Prot record with not associated valid GO.
+        """
+        print("Parsing swiss uniprot raw data....")
+
+        swiss_ids, sequences = [], []
+
+        swiss_data = SwissProt.parse(
+            open(
+                os.path.join(
+                    self._go_uniprot_extractor.raw_dir,
+                    self._go_uniprot_extractor.raw_file_names_dict["SwissUniProt"],
+                ),
+                "r",
+            )
+        )
+
+        for record in swiss_data:
+            if record.data_class != "Reviewed":
+                # To consider only manually-annotated swiss data
+                continue
+
+            if not record.sequence:
+                # Consider protein with only sequence representation
+                continue
+
+            if len(record.sequence) > self.max_sequence_length:
+                # Consider protein with only sequence length not greater than max seq. length
+                continue
+
+            if any(aa in AMBIGUOUS_AMINO_ACIDS for aa in record.sequence):
+                # Skip proteins with ambiguous amino acid codes
+                continue
+
+            has_valid_associated_go_label = False
+            for cross_ref in record.cross_references:
+                if cross_ref[0] == self._go_uniprot_extractor._GO_DATA_INIT:
+
+                    if len(cross_ref) <= 3:
+                        # No evidence code
+                        continue
+
+                    # https://github.com/bio-ontology-research-group/deepgo/blob/master/get_functions.py#L63-L66
+                    evidence_code = cross_ref[3].split(":")[0]
+                    if evidence_code in EXPERIMENTAL_EVIDENCE_CODES:
+                        has_valid_associated_go_label = True
+                        break
+
+            if has_valid_associated_go_label:
+                # Skip proteins which has at least one associated go label
+                continue
+
+            swiss_ids.append(record.entry_name)
+            sequences.append(record.sequence)
+
+        data_dict = OrderedDict(
+            swiss_id=swiss_ids,  # swiss_id column at index 0
+            sequence=sequences,  # Sequence column at index 1
+        )
+
+        return pd.DataFrame(data_dict)
+
+    # ------------------------------ Phase: Setup data -----------------------------------
+    def _load_dict(self, input_file_path: str) -> Generator[Dict[str, Any], None, None]:
+        """
+        Loads data from a pickled file and yields individual dictionaries for each row.
+
+        The pickled file is expected to contain rows with the following structure:
+            - Data at row index `self._ID_IDX`: ID of go data instance
+            - Data at row index `self._DATA_REPRESENTATION_IDX`: Sequence representation of protein
+
+        This method is used by `_load_data_from_file` to generate dictionaries that are then
+        processed and converted into a list of dictionaries containing the features and labels.
+
+        Args:
+            input_file_path (str): The path to the pickled input file.
+
+        Yields:
+            Dict[str, Any]: A dictionary containing:
+                - `features` (str): The sequence data from the file.
+                - `ident` (Any): The identifier from row index 0.
+                - `labels`: Set to None
+        """
+        with open(input_file_path, "rb") as input_file:
+            df = pd.read_pickle(input_file)
+            for row in df.values:
+                yield dict(
+                    features=row[self._DATA_REPRESENTATION_IDX],
+                    ident=row[self._ID_IDX],
+                    labels=None,
+                )
+
+    # ------------------------------ Phase: Dynamic Splits -----------------------------------
+    def _get_data_splits(self) -> Tuple[pd.DataFrame, pd.DataFrame, pd.DataFrame]:
+        """
+        Loads encoded data and generates training, validation, and test splits.
+
+        This method attempts to load encoded data from a file named `data.pt`. It then splits this data into
+        training, validation, and test sets.
+
+        Raises:
+            FileNotFoundError: If the `data.pt` file does not exist. Ensure that `prepare_data` and/or
+            `setup` methods are called to generate the necessary dataset files.
+
+        Returns:
+            Tuple[pd.DataFrame, pd.DataFrame, pd.DataFrame]: A tuple containing three DataFrames:
+                - Training set
+                - Validation set
+                - Test set
+        """
+        try:
+            filename = self.processed_file_names_dict["data"]
+            data_go = torch.load(
+                os.path.join(self.processed_dir, filename), weights_only=False
+            )
+        except FileNotFoundError:
+            raise FileNotFoundError(
+                f"File data.pt doesn't exists. "
+                f"Please call 'prepare_data' and/or 'setup' methods to generate the dataset files"
+            )
+
+        df_go_data = pd.DataFrame(data_go)
+        train_df_go, df_test = train_test_split(
+            df_go_data,
+            train_size=self.train_split,
+            random_state=self.dynamic_data_split_seed,
+        )
+
+        # Get all splits
+        df_train, df_val = train_test_split(
+            train_df_go,
+            train_size=self.train_split,
+            random_state=self.dynamic_data_split_seed,
+        )
+
+        return df_train, df_val, df_test
+
+    # ------------------------------ Phase: Raw Properties -----------------------------------
+    @property
+    def base_dir(self) -> str:
+        """
+        str: The base directory for pretraining data storage.
+        """
+        return os.path.join(self._go_uniprot_extractor.base_dir, "Pretraining")
+
+    @property
+    def raw_dir(self) -> str:
+        """Name of the directory where the raw data is stored."""
+        return self._go_uniprot_extractor.raw_dir
+
+
+class SwissProteinPretrain(_ProteinPretrainingData):
+    """
+    Data module for Swiss-Prot protein pretraining, inheriting from `_ProteinPretrainingData`.
+    This class is specifically designed to handle data processing and loading for Swiss-Prot-based protein datasets.
+
+    Attributes:
+        READER (Type): The data reader class used to load and process protein pretraining data.
+    """
+
+    READER = ProteinDataReader
+
+    @property
+    def _name(self) -> str:
+        """
+        The name identifier for this data module.
+
+        Returns:
+            str: A string identifier, "SwissProteinPretrain", representing the name of this data module.
+        """
+        return f"Swiss_{self.max_sequence_length}"
diff --git a/chebai/preprocessing/reader.py b/chebai/preprocessing/reader.py
index 46cd558a..e220e1e4 100644
--- a/chebai/preprocessing/reader.py
+++ b/chebai/preprocessing/reader.py
@@ -372,14 +372,16 @@ class ProteinDataReader(DataReader):
         "V",
     ]
 
-    @classmethod
-    def name(cls) -> str:
+    def name(self) -> str:
         """
         Returns the name of the data reader. This method identifies the specific type of data reader.
 
         Returns:
             str: The name of the data reader, which is "protein_token".
         """
+        if self.n_gram is not None:
+            return f"protein_token_{self.n_gram}_gram"
+
         return "protein_token"
 
     def __init__(self, *args, n_gram: Optional[int] = None, **kwargs):