If plugin enabled, then some games and homebrew refuses to launch

[st12q]

Model: PSP 300x (i don't remember last number)
Firmware: 6.61 Infinity 2.0 with PRO-CFW
Memory stick: 128 GB SD-card
Steps to reproduce:

1. Install plugin and enable it.
2. Launch some game or homebrew. Some games launch. Some don't. For example, Tekken 6 giving error in XMB. For homebrew it's just black screen.

[Freakler]

Its a known issue sadly and there is nothing I can do about it. Some games can't handle other plugins being loaded in memory.
You could try the ARK Custom Firmware which lets you register plugins per game.