Applying Mods to Specific Character Saves and Playthroughs

[GumbyXGames]

Is they a way to "set" a collection of mods to a specific character playthrough or would that have to be done manually by creating a mod list for said playthrough and loading it up when playing that playthrough? I want to started a new playthrough using different mods than what I used in my nain playthrough. I'm not sure how to do this without possibility screwing up the saves or having tons of mods loaded that I won't use (race and class mods for example).

[FrankLOrignal]

Trying to figure this out as well.