[PA165980774] Bad GPML for Uric Acid-Lowering Drugs Pathway, Pharmacodynamics

[pharmgen]

Latest GPML for pathwayPA165980774 is obsolete.
Use this instead: PA165980774-new.gpml

Note that even the updated GPML has errors that must be fixed:

• 'Hydrogen Peroxide' [id:a06e0]: Missing PharmGKB Accession ID.
• 'oxypurinol' [id:a2923]: Missing cellular location.
• 'fructose-1-phosphate' [id:a519a]: Missing PharmGKB Accession ID.
• 'hydrogen peroxide' [id:a5373]: Missing PharmGKB Accession ID.
• 'Uric Acid' [id:a5bc8]: Missing PharmGKB Accession ID.
• 'excretion via the bile' [id:a6d05]: Missing PharmGKB Accession ID.
• 'excretion via the bile' [id:a6d05]: BlackBox should be converted to Phenotype or Process.
• 'Allantoin' [id:a9aa0]: Missing PharmGKB Accession ID.
• 'Uricosurics Pathway, Pharmacodynamics' [id:ad8cf]: Missing cellular location.
• 'NADPH' [id:b0307]: Missing PharmGKB Accession ID.
• 'excretion via the renal proximal tubule' [id:b0e21]: Missing PharmGKB Accession ID.
• 'excretion via the renal proximal tubule' [id:b0e21]: BlackBox should be converted to Phenotype or Process.
• 'Uric Acid' [id:b132e]: Missing PharmGKB Accession ID.
• 'ATP' [id:b5934]: Missing PharmGKB Accession ID.
• 'severe cutaneous adverse reactions (SCARs)' [id:b9b9e]: Missing PharmGKB Accession ID.
• 'severe cutaneous adverse reactions (SCARs)' [id:b9b9e]: BlackBox should be converted to Phenotype or Process.
• '5-hydroxyisourate' [id:cab86]: Missing PharmGKB Accession ID.
• 'NADP' [id:cef8e]: Missing PharmGKB Accession ID.
• 'AMP' [id:da587]: Missing PharmGKB Accession ID.
• 'Urate Oxidase' [id:dbb4c]: Drug Collection must specify memberDrugs.
• 'Hypoxanthine' [id:e3505]: Missing PharmGKB Accession ID.
• 'Xanthine' [id:ea0af]: Missing PharmGKB Accession ID.
• 'Purine Catabolism Pathway' [id:ea12c]: Missing PharmGKB Accession ID.
• 'Purine Catabolism Pathway' [id:ea12c]: BlackBox should be converted to Phenotype or Process.
• 'HLA-B *58:01' [id:eaaf7]: Missing cellular location.
• 'excretion via the gastrointestinal tract' [id:f5b96]: Missing PharmGKB Accession ID.
• 'excretion via the gastrointestinal tract' [id:f5b96]: BlackBox should be converted to Phenotype or Process.
• 'allopurinol' [id:c2299]: Missing cellular location.
• Info Line line [id:a15e7] (from 'Hyperuricemia' [id:ffbd0] to 'Gout' [id:cfcda]): Info labels lines are no longer allowed.
• Transport line [id:a5695] (from 'AMP' [id:da587] to 'Purine Catabolism Pathway' [id:ea12c]): Transport does not have same entity on both ends.
• Info Line line [id:acb41] (from 'Hyperuricemia' [id:ffbd0] to 'Kidney Failure' [id:f2abd]): Info labels lines are no longer allowed.
• Info Line line [id:ad8d5] (from 'Uric Acid' [id:a5bc8] to 'excretion via the gastrointestinal tract' [id:f5b96]): Info labels lines are no longer allowed.
• Transport line [id:b1e7e] (from 'NADPH' [id:b0307] to 'Methylene Blue Pathway, Pharmacodynamics' [id:f51a7]): Transport does not have same entity on both ends.
• Transport line [id:b1e7e] (from 'NADPH' [id:b0307] to 'Methylene Blue Pathway, Pharmacodynamics' [id:f51a7]): Missing evidence.
• Transport line [id:b4ffd] (from 'fructose' [id:b0ead] to 'SLC2A5' [id:a5368]): Transport does not have same entity on both ends.
• Info Line line [id:bfda3] (from 'Uric Acid' [id:a5bc8] to 'excretion via the renal proximal tubule' [id:b0e21]): Info labels lines are no longer allowed.
• Biochemical Reaction line [id:d4583] (from 'NADP' [id:cef8e] to 'NADPH' [id:b0307]): Missing evidence.
• Biochemical Reaction line [id:d853c] (from 'allopurinol' [id:c2299] to 'severe cutaneous adverse reactions (SCARs)' [id:b9b9e]): Missing evidence.
• Transport line [id:dc5d1] (from 'Uricosurics Pathway, Pharmacodynamics' [id:ad8cf] to 'Uric Acid' [id:a5bc8]): Transport does not have same entity on both ends.
• Transport line [id:dc5d1] (from 'Uricosurics Pathway, Pharmacodynamics' [id:ad8cf] to 'Uric Acid' [id:a5bc8]): Missing evidence.
• Transport line [id:df820] (from 'Hydrogen Peroxide' [id:a06e0] to 'hydrogen peroxide' [id:a5373]): Transport does not have same entity on both ends.
• Transport line [id:df820] (from 'Hydrogen Peroxide' [id:a06e0] to 'hydrogen peroxide' [id:a5373]): Missing evidence.
• Biochemical Reaction line [id:e7099] (from 'oxypurinol' [id:a2923] to 'severe cutaneous adverse reactions (SCARs)' [id:b9b9e]): Missing evidence.
• Info Line line [id:edc1c] (from 'excretion via the renal proximal tubule' [id:b0e21] to 'Uricosurics Pathway, Pharmacodynamics' [id:ad8cf]): Info labels lines are no longer allowed.
• Transport line [id:ef321] (from 'Uric Acid' [id:b132e] to 'Uric Acid' [id:a5bc8]): Missing evidence.
• Info Line line [id:bc373] (from 'Uric Acid' [id:a5bc8] to 'excretion via the bile' [id:a6d05]): Info labels lines are no longer allowed.
• Transport line [id:ebbc3] (from 'SLC2A5' [id:a5368] to 'fructose' [id:af31b]): Transport does not have same entity on both ends.
• Transport line [id:b8e70] (from 'NADPH' [id:b0307] to 'Pentose Phosphate Pathway (Erthrocyte)' [id:aebac]): Transport does not have same entity on both ends.
• Transport line [id:b8e70] (from 'NADPH' [id:b0307] to 'Pentose Phosphate Pathway (Erthrocyte)' [id:aebac]): Missing evidence.
• Transport line [id:df882] (from 'NADPH' [id:b0307] to 'Oxidative Stress Regulatory Pathway (Erythrocyte)' [id:e6860]): Transport does not have same entity on both ends.
• Transport line [id:df882] (from 'NADPH' [id:b0307] to 'Oxidative Stress Regulatory Pathway (Erythrocyte)' [id:e6860]): Missing evidence.
• 'Kidney Failure' [id:f2abd]: Not linked to anything.
• 'excretion via the bile' [id:a6d05]: Not linked to anything.
• 'excretion via the gastrointestinal tract' [id:f5b96]: Not linked to anything.
• 'excretion via the renal proximal tubule' [id:b0e21]: Not linked to anything.
• 'Gout' [id:cfcda]: Not linked to anything.