diff --git a/packages/typescript/ai-openai/src/model-meta.ts b/packages/typescript/ai-openai/src/model-meta.ts
index 024a6c1a..13c38c86 100644
--- a/packages/typescript/ai-openai/src/model-meta.ts
+++ b/packages/typescript/ai-openai/src/model-meta.ts
@@ -1,4 +1,5 @@
 import type {
+  OpenAIAudioOutputOptions,
   OpenAIBaseOptions,
   OpenAIMetadataOptions,
   OpenAIReasoningOptions,
@@ -1072,6 +1073,32 @@ const GPT_4O_AUDIO = {
     OpenAIMetadataOptions
 >
 
+const GPT_4O_AUDIO_PREVIEW = {
+  name: 'gpt-4o-audio-preview',
+  context_window: 128_000,
+  max_output_tokens: 16_384,
+  knowledge_cutoff: '2023-10-01',
+  pricing: {
+    input: {
+      normal: 2.5,
+    },
+    output: {
+      normal: 10,
+    },
+  },
+  supports: {
+    input: ['text', 'audio'],
+    output: ['text', 'audio'],
+    endpoints: ['chat-completions'],
+    features: ['streaming', 'function_calling'],
+  },
+} as const satisfies ModelMeta<
+  OpenAIBaseOptions &
+    OpenAIToolsOptions &
+    OpenAIStreamingOptions &
+    OpenAIMetadataOptions
+>
+
 const GPT_4O_MINI = {
   name: 'gpt-4o-mini',
   context_window: 128_000,
@@ -1635,6 +1662,7 @@ export const OPENAI_CHAT_MODELS = [
   GPT_AUDIO.name,
   GPT_AUDIO_MINI.name,
   GPT_4O_AUDIO.name,
+  GPT_4O_AUDIO_PREVIEW.name,
   GPT_4O_MINI_AUDIO.name,
   // ChatGPT models
   GPT_5_1_CHAT.name,
@@ -1879,16 +1907,24 @@ export type OpenAIChatModelProviderOptionsByName = {
   // Audio models
   [GPT_AUDIO.name]: OpenAIBaseOptions &
     OpenAIStreamingOptions &
-    OpenAIMetadataOptions
+    OpenAIMetadataOptions &
+    OpenAIAudioOutputOptions
   [GPT_AUDIO_MINI.name]: OpenAIBaseOptions &
     OpenAIStreamingOptions &
-    OpenAIMetadataOptions
+    OpenAIMetadataOptions &
+    OpenAIAudioOutputOptions
   [GPT_4O_AUDIO.name]: OpenAIBaseOptions &
     OpenAIStreamingOptions &
-    OpenAIMetadataOptions
+    OpenAIMetadataOptions &
+    OpenAIAudioOutputOptions
+  [GPT_4O_AUDIO_PREVIEW.name]: OpenAIBaseOptions &
+    OpenAIStreamingOptions &
+    OpenAIMetadataOptions &
+    OpenAIAudioOutputOptions
   [GPT_4O_MINI_AUDIO.name]: OpenAIBaseOptions &
     OpenAIStreamingOptions &
-    OpenAIMetadataOptions
+    OpenAIMetadataOptions &
+    OpenAIAudioOutputOptions
 
   // Chat-only models
   [GPT_5_1_CHAT.name]: OpenAIBaseOptions &
@@ -1974,6 +2010,7 @@ export type OpenAIModelInputModalitiesByName = {
   [GPT_AUDIO.name]: typeof GPT_AUDIO.supports.input
   [GPT_AUDIO_MINI.name]: typeof GPT_AUDIO_MINI.supports.input
   [GPT_4O_AUDIO.name]: typeof GPT_4O_AUDIO.supports.input
+  [GPT_4O_AUDIO_PREVIEW.name]: typeof GPT_4O_AUDIO_PREVIEW.supports.input
   [GPT_4O_MINI_AUDIO.name]: typeof GPT_4O_MINI_AUDIO.supports.input
 
   // Text-only models
diff --git a/packages/typescript/ai-openai/src/openai-adapter.ts b/packages/typescript/ai-openai/src/openai-adapter.ts
index 676d5257..b5df957e 100644
--- a/packages/typescript/ai-openai/src/openai-adapter.ts
+++ b/packages/typescript/ai-openai/src/openai-adapter.ts
@@ -89,6 +89,172 @@ export class OpenAI extends BaseAdapter<
 
   async *chatStream(
     options: ChatOptions<string, OpenAIProviderOptions>,
+  ): AsyncIterable<StreamChunk> {
+    // Check if audio output is requested via providerOptions
+    const providerOptions = options.providerOptions as
+      | ExternalTextProviderOptions
+      | undefined
+    const hasAudioOutput = providerOptions?.modalities?.includes('audio')
+
+    if (hasAudioOutput) {
+      // Use Chat Completions API for audio output
+      yield* this.chatStreamWithAudio(options)
+    } else {
+      // Use Responses API for standard text/tool use cases
+      yield* this.chatStreamWithResponses(options)
+    }
+  }
+
+  /**
+   * Stream using Chat Completions API with audio output support.
+   * Required for models like gpt-4o-audio-preview that support audio modalities.
+   */
+  private async *chatStreamWithAudio(
+    options: ChatOptions<string, OpenAIProviderOptions>,
+  ): AsyncIterable<StreamChunk> {
+    const providerOptions = options.providerOptions as
+      | ExternalTextProviderOptions
+      | undefined
+    const timestamp = Date.now()
+
+    try {
+      // Build Chat Completions API request
+      const messages = this.convertMessagesToChatCompletions(options.messages)
+
+      // Add system prompt if provided
+      if (options.systemPrompts && options.systemPrompts.length > 0) {
+        messages.unshift({
+          role: 'system',
+          content: options.systemPrompts.join('\n'),
+        })
+      }
+
+      const response = await this.client.chat.completions.create({
+        model: options.model,
+        messages,
+        modalities: providerOptions?.modalities,
+        audio: providerOptions?.audio,
+        temperature: options.options?.temperature,
+        max_completion_tokens: options.options?.maxTokens,
+        top_p: options.options?.topP,
+        stream: true,
+      })
+
+      let accumulatedContent = ''
+      let responseId = this.generateId()
+
+      for await (const chunk of response) {
+        const choice = chunk.choices[0]
+        if (!choice) continue
+
+        const delta = choice.delta as {
+          content?: string | null
+          audio?: { transcript?: string; data?: string }
+        }
+
+        // Handle text content delta
+        if (delta.content) {
+          accumulatedContent += delta.content
+          yield {
+            type: 'content',
+            id: responseId,
+            model: options.model,
+            timestamp,
+            delta: delta.content,
+            content: accumulatedContent,
+            role: 'assistant',
+          }
+        }
+
+        // Handle audio transcript (also counts as content)
+        if (delta.audio?.transcript) {
+          accumulatedContent += delta.audio.transcript
+          yield {
+            type: 'content',
+            id: responseId,
+            model: options.model,
+            timestamp,
+            delta: delta.audio.transcript,
+            content: accumulatedContent,
+            role: 'assistant',
+          }
+        }
+
+        // Handle audio data
+        if (delta.audio?.data) {
+          yield {
+            type: 'audio',
+            id: responseId,
+            model: options.model,
+            timestamp,
+            data: delta.audio.data,
+            transcript: delta.audio.transcript,
+            format: providerOptions?.audio?.format,
+          }
+        }
+
+        // Handle finish
+        if (choice.finish_reason) {
+          yield {
+            type: 'done',
+            id: responseId,
+            model: options.model,
+            timestamp,
+            finishReason:
+              choice.finish_reason === 'stop'
+                ? 'stop'
+                : choice.finish_reason === 'length'
+                  ? 'length'
+                  : choice.finish_reason === 'content_filter'
+                    ? 'content_filter'
+                    : null,
+            usage: chunk.usage
+              ? {
+                  promptTokens: chunk.usage.prompt_tokens,
+                  completionTokens: chunk.usage.completion_tokens,
+                  totalTokens: chunk.usage.total_tokens,
+                }
+              : undefined,
+          }
+        }
+      }
+    } catch (error: any) {
+      console.error(
+        '>>> chatStreamWithAudio: Error during audio streaming <<<',
+      )
+      console.error('>>> Error message:', error?.message)
+      yield {
+        type: 'error',
+        id: this.generateId(),
+        model: options.model,
+        timestamp,
+        error: {
+          message: error.message || 'Unknown error occurred',
+          code: error.code,
+        },
+      }
+    }
+  }
+
+  /**
+   * Convert ModelMessage array to Chat Completions API format.
+   */
+  private convertMessagesToChatCompletions(
+    messages: Array<ModelMessage>,
+  ): Array<{ role: 'system' | 'user' | 'assistant'; content: string }> {
+    return messages
+      .filter((m) => m.role !== 'tool') // Filter out tool messages for now
+      .map((m) => ({
+        role: m.role as 'user' | 'assistant',
+        content: this.extractTextContent(m.content),
+      }))
+  }
+
+  /**
+   * Stream using Responses API (default for non-audio use cases).
+   */
+  private async *chatStreamWithResponses(
+    options: ChatOptions<string, OpenAIProviderOptions>,
   ): AsyncIterable<StreamChunk> {
     // Track tool call metadata by unique ID
     // OpenAI streams tool calls with deltas - first chunk has ID/name, subsequent chunks only have args
@@ -108,7 +274,7 @@ export class OpenAI extends BaseAdapter<
         },
       )
 
-      // Chat Completions API uses SSE format - iterate directly
+      // Responses API uses SSE format - iterate directly
       yield* this.processOpenAIStreamChunks(
         response,
         toolCallMetadata,
diff --git a/packages/typescript/ai-openai/src/text/text-provider-options.ts b/packages/typescript/ai-openai/src/text/text-provider-options.ts
index ba9d6049..78ccacbb 100644
--- a/packages/typescript/ai-openai/src/text/text-provider-options.ts
+++ b/packages/typescript/ai-openai/src/text/text-provider-options.ts
@@ -234,12 +234,57 @@ https://platform.openai.com/docs/api-reference/responses/create#responses_create
   metadata?: Record<string, string>
 }
 
+/**
+ * Audio output options for models that support audio generation (e.g., gpt-4o-audio-preview).
+ * When specified, the model will generate audio output in addition to or instead of text.
+ * Note: Audio output requires the Chat Completions API, not the Responses API.
+ * @see https://platform.openai.com/docs/guides/audio
+ */
+export interface OpenAIAudioOutputOptions {
+  /**
+   * Output modalities to generate. Include 'audio' to enable audio output.
+   * Example: ['text', 'audio'] for both text and audio output.
+   */
+  modalities?: Array<'text' | 'audio'>
+  /**
+   * Audio output configuration. Required when modalities includes 'audio'.
+   */
+  audio?: {
+    /**
+     * The voice to use for audio generation.
+     * Available voices: alloy, ash, ballad, coral, echo, fable, onyx, nova, sage, shimmer, verse
+     */
+    voice:
+      | 'alloy'
+      | 'ash'
+      | 'ballad'
+      | 'coral'
+      | 'echo'
+      | 'fable'
+      | 'onyx'
+      | 'nova'
+      | 'sage'
+      | 'shimmer'
+      | 'verse'
+    /**
+     * The audio format for output.
+     * - 'pcm16': Raw 16-bit PCM audio at 24kHz (best for real-time streaming)
+     * - 'wav': WAV format
+     * - 'mp3': MP3 format
+     * - 'opus': Opus format
+     * - 'flac': FLAC format
+     */
+    format: 'pcm16' | 'wav' | 'mp3' | 'opus' | 'flac'
+  }
+}
+
 export type ExternalTextProviderOptions = OpenAIBaseOptions &
   OpenAIReasoningOptions &
   OpenAIStructuredOutputOptions &
   OpenAIToolsOptions &
   OpenAIStreamingOptions &
-  OpenAIMetadataOptions
+  OpenAIMetadataOptions &
+  OpenAIAudioOutputOptions
 
 /**
  * Options your SDK forwards to OpenAI when doing chat/responses.
diff --git a/packages/typescript/ai/src/types.ts b/packages/typescript/ai/src/types.ts
index 748526c2..3d2f16e3 100644
--- a/packages/typescript/ai/src/types.ts
+++ b/packages/typescript/ai/src/types.ts
@@ -583,6 +583,7 @@ export interface ChatOptions<
 
 export type StreamChunkType =
   | 'content'
+  | 'audio'
   | 'tool_call'
   | 'tool_result'
   | 'done'
@@ -666,11 +667,26 @@ export interface ThinkingStreamChunk extends BaseStreamChunk {
   content: string // Full accumulated thinking content so far
 }
 
+/**
+ * Audio output stream chunk for models that support audio output (e.g., gpt-4o-audio-preview).
+ * Contains base64-encoded audio data and optional transcript.
+ */
+export interface AudioStreamChunk extends BaseStreamChunk {
+  type: 'audio'
+  /** Base64-encoded audio data (e.g., PCM16, WAV) */
+  data: string
+  /** Optional transcript of the audio content */
+  transcript?: string
+  /** Audio format (e.g., 'pcm16', 'wav', 'mp3') */
+  format?: string
+}
+
 /**
  * Chunk returned by the sdk during streaming chat completions.
  */
 export type StreamChunk =
   | ContentStreamChunk
+  | AudioStreamChunk
   | ToolCallStreamChunk
   | ToolResultStreamChunk
   | DoneStreamChunk