I recently switched from the pulse to the pipewire output method.
With the voice I use (Vocaalizer's Thomas Pro french voice, Voxin 4.3), the
sound is of less good quality when output via pipewire as what I had with
pulseaudio.
I don't know exactly how to describe the change, it's as if the voice is
less clear and distinct with pipewire than with pulseaudio.
Would it help to provide audio clips from the two outputs?