diff --git a/README.md b/README.md
index 4fa2c54..90951ed 100644
--- a/README.md
+++ b/README.md
@@ -41,6 +41,7 @@ bwa|0.7.17-r1188|docker pull pgc-images.sbgenomics.com/d3b-bixu/bwa:0.7.17-r1188
 bwa|latest|docker pull pgc-images.sbgenomics.com/d3b-bixu/bwa:latest
 canvas|1.11.0|docker pull pgc-images.sbgenomics.com/d3b-bixu/canvas:1.11.0
 cbio-etl|v2.4.4|docker pull pgc-images.sbgenomics.com/d3b-bixu/cbio-etl:v2.4.4
+cbio-etl|v2.4.6|docker pull pgc-images.sbgenomics.com/d3b-bixu/cbio-etl:v2.4.6
 cellranger|3.1|docker pull pgc-images.sbgenomics.com/d3b-bixu/cellranger:3.1
 cellranger|5.0|docker pull pgc-images.sbgenomics.com/d3b-bixu/cellranger:5.0
 cellranger|6.0|docker pull pgc-images.sbgenomics.com/d3b-bixu/cellranger:6.0
diff --git a/cbio-etl/v2.4.6/Dockerfile b/cbio-etl/v2.4.6/Dockerfile
new file mode 100644
index 0000000..4dccd7c
--- /dev/null
+++ b/cbio-etl/v2.4.6/Dockerfile
@@ -0,0 +1,34 @@
+ARG PLATFORM=linux/amd64
+FROM --platform=${PLATFORM} ubuntu:24.04
+
+LABEL maintainer="Miguel Brown <brownm28@chop.edu>"
+LABEL description="cbio-etl"
+
+ENV DEBIAN_FRONTEND=noninteractive
+
+RUN apt update && apt install -y \
+    apt-utils \
+    git \
+    curl \
+    vim \
+    python3 \
+    python3-pip \
+    python3-dev \
+    pkg-config \
+    build-essential \
+    bedtools \
+    && rm -rf /var/lib/apt/lists/*
+
+WORKDIR /
+
+ENV CBIO_ETL_VERSION=2.4.6
+ENV CBIO_REFS_VERSION=1.1.1
+
+RUN git clone https://github.com/kids-first/kf-cbioportal-etl.git \
+    && cd kf-cbioportal-etl \
+    && git checkout v${CBIO_ETL_VERSION} \
+    && curl -L https://github.com/kids-first/kf-cbioportal-etl-refs/archive/refs/tags/v${CBIO_REFS_VERSION}.tar.gz | tar -xz -C cbioportal_etl/ --wildcards '*REFS/*' --strip-components=1 \
+    && curl -L https://github.com/kids-first/kf-cbioportal-etl-refs/archive/refs/tags/v${CBIO_REFS_VERSION}.tar.gz | tar -xz -C cbioportal_etl/ --wildcards '*STUDY_CONFIGS/*' --strip-components=1 \
+    && pip install --break-system-packages .
+    
+COPY Dockerfile .