Error in solve.QP(D, d, A, bzero)

[Susanxuan]

Dear DWLS developer,

I found your method appealing and would like to apply it on our personalized data. I am currently stuck at running solveDampenedWLS() with part of the samples(while others works fine). I get the Error:

Error in solve.QP(D, d, A, bzero): constraints are inconsistent, no solution!
Traceback:
1. solveDampenedWLS(S, B)
2. solveOLSInternal(S, B)
3. solve.QP(D, d, A, bzero)
4. stop("constraints are inconsistent, no solution!")

Can you suggest a way I can fix this issue?

Thank you!

[MEladawi]

Same here

[xlucpu]

same here

[amandaqiuuu]

same here

[XiQiao2023]

Same here

[RLau0]

Testing out this package as well and I don't know what inputs you all put in but I found one thing that is not made clear in the manual. You are not putting your whole RNA-seq matrix into the solveDampenedWLS(). You put in the RNA-seq for one sample at a time (so a named vector). This can be seen in concept with the ISC_pipeline they provide.