Maximum recursion depth exceeded while calling a Python object when trying to run Milopy

[ahmed-agami]

Hello...everyone I keep receiving this error whenever I try to run the following code:

DA_nhoods(adata_Epi, design="~condition_continuous")

---

RecursionError Traceback (most recent call last)
/tmp/ipykernel_654903/4015237463.py in
----> 1 DA_nhoods(adata_Epi, design="~condition_continuous")

~/yes/envs/sc_analysis/lib/python3.8/site-packages/milopy/core.py in DA_nhoods(adata, design, model_contrasts, subset_samples, add_intercept)
253 dge = edgeR.DGEList(
254 counts=count_mat[keep_nhoods, :][:, keep_smp], lib_size=lib_size[keep_smp])
--> 255 dge = edgeR.calcNormFactors(dge, method="TMM")
256 dge = edgeR.estimateDisp(dge, model)
257 fit = edgeR.glmQLFit(dge, model, robust=True)

~/yes/envs/sc_analysis/lib/python3.8/site-packages/rpy2/robjects/functions.py in call(self, *args, **kwargs)
206 v = kwargs.pop(k)
207 kwargs[r_k] = v
--> 208 return (super(SignatureTranslatedFunction, self)
209 .call(*args, **kwargs))
210

~/yes/envs/sc_analysis/lib/python3.8/site-packages/rpy2/robjects/functions.py in call(self, *args, **kwargs)
121 def call(self, *args, **kwargs):
122 cv = conversion.get_conversion()
--> 123 new_args = [cv.py2rpy(a) for a in args]
124 new_kwargs = {}
125 for k, v in kwargs.items():

~/yes/envs/sc_analysis/lib/python3.8/site-packages/rpy2/robjects/functions.py in (.0)
121 def call(self, *args, **kwargs):
122 cv = conversion.get_conversion()
--> 123 new_args = [cv.py2rpy(a) for a in args]
124 new_kwargs = {}
125 for k, v in kwargs.items():

~/yes/envs/sc_analysis/lib/python3.8/functools.py in wrapper(*args, **kw)
873 '1 positional argument')
874
--> 875 return dispatch(args[0].class)(*args, **kw)
876
877 funcname = getattr(func, 'name', 'singledispatch function')

~/yes/envs/sc_analysis/lib/python3.8/site-packages/rpy2/robjects/numpy2ri.py in nonnumpy2rpy(obj)
141 else:
142 # The conversion module was "activated"
--> 143 return original_converter.py2rpy(obj)
144
145

... last 2 frames repeated, from the frame below ...

~/yes/envs/sc_analysis/lib/python3.8/functools.py in wrapper(*args, **kw)
873 '1 positional argument')
874
--> 875 return dispatch(args[0].class)(*args, **kw)
876
877 funcname = getattr(func, 'name', 'singledispatch function')

RecursionError: maximum recursion depth exceeded while calling a Python object

Do you have any suggestions? Has anyone else experienced the same error here? I tried to set the recursion limit even higher by using sys.setrecursionlimit() but also it didn't work and the notebook crashed