diff --git a/.github/workflows/autofmt.yml b/.github/workflows/autofmt.yml
index 6a96677a..bd2c2e4b 100644
--- a/.github/workflows/autofmt.yml
+++ b/.github/workflows/autofmt.yml
@@ -12,7 +12,7 @@ jobs:
           - name: Set up Python
             uses: actions/setup-python@v5
             with:
-              python-version: 3.8
+              python-version: 3.9
           - name: Install ruff
             run: pip install ruff==0.6.9
           - name: Check format
diff --git a/.github/workflows/autotest.yml b/.github/workflows/autotest.yml
index 2e7ad7f4..0fb7ac20 100644
--- a/.github/workflows/autotest.yml
+++ b/.github/workflows/autotest.yml
@@ -10,7 +10,7 @@ jobs:
     strategy:
       matrix:
         os: [windows-latest]
-        python-version: ['3.8', '3.9', '3.10', '3.11', '3.12', '3.13']
+        python-version: ['3.9', '3.10', '3.11', '3.12', '3.13', '3.14']
         architecture: ['x86', 'x64']
         support: ['with 3rd parties', 'without 3rd parties']
     steps:
@@ -51,7 +51,7 @@ jobs:
     strategy:
       matrix:
         os: [windows-2025, windows-2022]
-        python-version: ['3.8', '3.9', '3.10', '3.11', '3.12', '3.13']
+        python-version: ['3.9', '3.10', '3.11', '3.12', '3.13', '3.14']
         architecture: ['x86', 'x64']
     steps:
       - uses: actions/checkout@v4
diff --git a/README.md b/README.md
index fedd4f78..3fad6ff5 100644
--- a/README.md
+++ b/README.md
@@ -11,11 +11,11 @@
 
 `comtypes` allows you to define, call, and implement custom and dispatch-based COM interfaces in pure Python.
 
-`comtypes` requires Windows and Python 3.8 or later.
+`comtypes` requires Windows and Python 3.9 or later.
+- Version [1.4.12](https://pypi.org/project/comtypes/1.4.12/) is the last version to support Python 3.8.
 - Version <= [1.4.7](https://pypi.org/project/comtypes/1.4.7/) does not work with Python 3.13 as reported in [GH-618](https://github.com/enthought/comtypes/issues/618). Version [1.4.8](https://pypi.org/project/comtypes/1.4.8/) can work with Python 3.13.
 - Version [1.4.6](https://pypi.org/project/comtypes/1.4.6/) is the last version to support Python 3.7.
 - Version [1.2.1](https://pypi.org/project/comtypes/1.2.1/) is the last version to support Python 2.7 and 3.3–3.6.
-- `comtypes` does not work with Python 3.8.1 as reported in [GH-202](https://github.com/enthought/comtypes/issues/202). This bug has been fixed in Python >= 3.8.2.
 - Certain `comtypes` functions may not work correctly in Python 3.8 and 3.9 as reported in [GH-212](https://github.com/enthought/comtypes/issues/212). This bug has been fixed in Python >= 3.10.10 and >= 3.11.2.
 
 ## Installation
diff --git a/comtypes/_meta.py b/comtypes/_meta.py
index f3631582..844aecd9 100644
--- a/comtypes/_meta.py
+++ b/comtypes/_meta.py
@@ -1,4 +1,5 @@
 # comtypes._meta helper module
+import sys
 from ctypes import POINTER, c_void_p, cast
 
 import comtypes
@@ -74,7 +75,7 @@ def __new__(cls, name, bases, namespace):
             # Depending on a version or revision of Python, this may be essential.
             return self
 
-        PTR = _coclass_pointer_meta(
+        p = _coclass_pointer_meta(
             f"POINTER({self.__name__})",
             (self, c_void_p),
             {
@@ -82,9 +83,12 @@ def __new__(cls, name, bases, namespace):
                 "from_param": classmethod(_coclass_from_param),
             },
         )
-        from ctypes import _pointer_type_cache  # type: ignore
+        if sys.version_info >= (3, 14):
+            self.__pointer_type__ = p
+        else:
+            from ctypes import _pointer_type_cache  # type: ignore
 
-        _pointer_type_cache[self] = PTR
+            _pointer_type_cache[self] = p
 
         return self
 
diff --git a/comtypes/_post_coinit/unknwn.py b/comtypes/_post_coinit/unknwn.py
index e11c0e91..f15dbf47 100644
--- a/comtypes/_post_coinit/unknwn.py
+++ b/comtypes/_post_coinit/unknwn.py
@@ -1,6 +1,7 @@
 # https://learn.microsoft.com/en-us/windows/win32/api/unknwn/
 
 import logging
+import sys
 from ctypes import HRESULT, POINTER, byref, c_ulong, c_void_p
 from typing import TYPE_CHECKING, Any, ClassVar, List, Optional, Type, TypeVar
 
@@ -126,9 +127,12 @@ def __new__(cls, name, bases, namespace):
             {"__com_interface__": self, "_needs_com_addref_": None},
         )
 
-        from ctypes import _pointer_type_cache  # type: ignore
+        if sys.version_info >= (3, 14):
+            self.__pointer_type__ = p
+        else:
+            from ctypes import _pointer_type_cache  # type: ignore
 
-        _pointer_type_cache[self] = p
+            _pointer_type_cache[self] = p
 
         if self._case_insensitive_:
             _meta_patch.case_insensitive(p)
diff --git a/comtypes/test/test_comserver.py b/comtypes/test/test_comserver.py
index c4bf0c53..13e4f9fc 100644
--- a/comtypes/test/test_comserver.py
+++ b/comtypes/test/test_comserver.py
@@ -1,4 +1,5 @@
 import doctest
+import sys
 import unittest
 from ctypes import pointer
 from typing import Any
@@ -140,6 +141,13 @@ class TestInproc_win32com(BaseServerTest, unittest.TestCase):
     def create_object(self):
         return Dispatch("TestComServerLib.TestComServer")
 
+    if sys.version_info >= (3, 14):
+
+        @unittest.skip("Fails occasionally with a memory leak on INPROC.")
+        def test_eval(self):
+            # This test sometimes leaks memory when run as an in-process server.
+            pass
+
     # These tests make no sense with win32com, override to disable them:
     @unittest.skip("This test make no sense with win32com.")
     def test_get_typeinfo(self):
diff --git a/comtypes/test/test_excel.py b/comtypes/test/test_excel.py
index dfb90a83..16f752c9 100644
--- a/comtypes/test/test_excel.py
+++ b/comtypes/test/test_excel.py
@@ -125,8 +125,7 @@ def test(self):
 
 @unittest.skipIf(IMPORT_FAILED, "This depends on Excel.")
 @unittest.skipIf(
-    sys.version_info[:2] == (3, 8)
-    or sys.version_info[:2] == (3, 9)
+    sys.version_info[:2] == (3, 9)
     or (sys.version_info[:2] == (3, 10) and sys.version_info < (3, 10, 10))
     or (sys.version_info[:2] == (3, 11) and sys.version_info < (3, 11, 2)),
     f"This fails in {PY_VER}. See https://github.com/enthought/comtypes/issues/212",
diff --git a/comtypes/util.py b/comtypes/util.py
index 155021f8..3d4c467a 100644
--- a/comtypes/util.py
+++ b/comtypes/util.py
@@ -2,6 +2,7 @@
 and cast_field(struct, fieldname, fieldtype).
 """
 
+import sys
 from ctypes import (
     POINTER,
     Structure,
@@ -15,6 +16,7 @@
     c_float,
     c_int,
     c_long,
+    c_longdouble,
     c_longlong,
     c_short,
     c_void_p,
@@ -38,17 +40,61 @@ def _calc_offset():
     # The definition of PyCArgObject in C code (that is the type of
     # object that a byref() call returns):
     class PyCArgObject(Structure):
+        if sys.version_info >= (3, 14):
+            # While C compilers automatically determine appropriate
+            # alignment based on field data types, `ctypes` requires
+            # explicit control over memory layout.
+            #
+            # `_pack_ = 8` ensures 8-byte alignment for fields.
+            #
+            # This works on both 32-bit and 64-bit systems:
+            # - On 64-bit systems, this matches the natural alignment
+            #   for pointers.
+            # - On 32-bit systems, this is more strict than necessary
+            #   (4-byte would be enough), but still produces the
+            #   correct memory layout with proper padding.
+            #
+            # With `_pack_`, `ctypes` will automatically add padding
+            # here to ensure proper alignment of the `value` field
+            # after the `tag` and after the `size`.
+            _pack_ = 8
+        else:
+            # No special packing needed for Python 3.13 and earlier
+            # because the default alignment works fine for the legacy
+            # structure.
+            pass
+
         class value(Union):
-            _fields_ = [
-                ("c", c_char),
-                ("h", c_short),
-                ("i", c_int),
-                ("l", c_long),
-                ("q", c_longlong),
-                ("d", c_double),
-                ("f", c_float),
-                ("p", c_void_p),
-            ]
+            if sys.version_info >= (3, 14):
+                # In Python 3.14, the tagPyCArgObject structure was
+                # modified to better support complex types.
+                _fields_ = [
+                    ("c", c_char),
+                    ("b", c_char),
+                    ("h", c_short),
+                    ("i", c_int),
+                    ("l", c_long),
+                    ("q", c_longlong),
+                    ("g", c_longdouble),
+                    ("d", c_double),
+                    ("f", c_float),
+                    ("p", c_void_p),
+                    # arrays for real and imaginary of complex
+                    ("D", c_double * 2),
+                    ("F", c_float * 2),
+                    ("G", c_longdouble * 2),
+                ]
+            else:
+                _fields_ = [
+                    ("c", c_char),
+                    ("h", c_short),
+                    ("i", c_int),
+                    ("l", c_long),
+                    ("q", c_longlong),
+                    ("d", c_double),
+                    ("f", c_float),
+                    ("p", c_void_p),
+                ]
 
         #
         # Thanks to Lenard Lindstrom for this tip:
@@ -66,9 +112,13 @@ class value(Union):
         _anonymous_ = ["value"]
 
     # additional checks to make sure that everything works as expected
-
-    if sizeof(PyCArgObject) != type(byref(c_int())).__basicsize__:
-        raise RuntimeError("sizeof(PyCArgObject) invalid")
+    expected_size = type(byref(c_int())).__basicsize__
+    actual_size = sizeof(PyCArgObject)
+    if actual_size != expected_size:
+        raise RuntimeError(
+            f"sizeof(PyCArgObject) mismatch: expected {expected_size}, "
+            f"got {actual_size}."
+        )
 
     obj = c_int()
     ref = byref(obj)
diff --git a/setup.cfg b/setup.cfg
index 7008bacb..bb98b1c2 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -18,7 +18,7 @@ classifiers =
 	Topic :: Software Development :: Libraries :: Python Modules
 
 [options]
-python_requires = >=3.8
+python_requires = >=3.9
 
 packages =
 	comtypes