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+"subsystem":"Transport, Peroxisomal", +"notes":{ +"original_bigg_ids":[ +"ASPDxt" +] +} +}, +{ +"id":"ASPGLUm", +"name":"Aspartate-glutamate mitochondrial shuttle", +"metabolites":{ +"asp__L_c":1.0, +"asp__L_m":-1.0, +"glu__L_c":-1.0, +"glu__L_m":1.0, +"h_c":-1.0, +"h_m":1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"10165_AT1 or 8604_AT1", +"subsystem":"Transport, Mitochondrial", +"notes":{ +"original_bigg_ids":[ +"ASPGLUm" +] +} +}, +{ +"id":"ASPNATm", +"name":"Aspartate N-acetyltransferase, mitochondrial", +"metabolites":{ +"Nacasp_m":1.0, +"accoa_m":-1.0, +"asp__L_m":-1.0, +"coa_m":1.0, +"h_m":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Alanine and Aspartate Metabolism", +"notes":{ +"original_bigg_ids":[ +"ASPNATm" +] +} +}, +{ +"id":"ASPTA", +"name":"Aspartate transaminase", +"metabolites":{ +"akg_c":-1.0, +"asp__L_c":-1.0, +"glu__L_c":1.0, +"oaa_c":1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"2805_AT1", +"subsystem":"Alanine and Aspartate Metabolism", +"notes":{ +"original_bigg_ids":[ +"ASPTA" +] +} +}, +{ +"id":"ASPTAm", +"name":"Aspartate transaminase", +"metabolites":{ +"akg_m":-1.0, +"asp__L_m":-1.0, +"glu__L_m":1.0, +"oaa_m":1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"2806_AT1", +"subsystem":"Alanine and Aspartate Metabolism", +"notes":{ +"original_bigg_ids":[ +"ASPTAm" +] +} +}, +{ +"id":"ASPt6", +"name":"L-aspartate transport via Na, H symport and K antiport", +"metabolites":{ +"asp__L_c":1.0, +"asp__L_e":-1.0, +"h_c":1.0, +"h_e":-1.0, +"k_c":-1.0, +"k_e":1.0, +"na1_c":3.0, +"na1_e":-3.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"6505_AT1 or 6506_AT1 or 6507_AT1 or 6511_AT1 or 6512_AT1", +"subsystem":"Transport, Extracellular", +"notes":{ +"original_bigg_ids":[ +"ASPt6" +] +} +}, +{ +"id":"ATP1ter", +"name":"ADP/ATP transporter, endoplasmic reticulum", +"metabolites":{ +"adp_c":1.0, +"adp_r":-1.0, +"atp_c":-1.0, +"atp_r":1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Endoplasmic Reticular", +"notes":{ +"original_bigg_ids":[ +"ATP1ter" +] +} +}, +{ +"id":"ATP2ter", +"name":"AMP/ATP transporter, endoplasmic reticulum", +"metabolites":{ +"amp_c":1.0, +"amp_r":-1.0, +"atp_c":-1.0, +"atp_r":1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Endoplasmic Reticular", +"notes":{ +"original_bigg_ids":[ +"ATP2ter" +] +} +}, +{ +"id":"ATPH1e", +"name":"ATP diphosphohydrolase", +"metabolites":{ +"amp_e":1.0, +"atp_e":-1.0, +"h2o_e":-2.0, +"h_e":2.0, +"pi_e":2.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"957_AT1 or 954_AT2 or 956_AT1 or 954_AT1 or 953_AT1 or 955_AT1", +"subsystem":"Nucleotides", +"notes":{ +"original_bigg_ids":[ +"ATPH1e" +] +} +}, +{ +"id":"ATPH2e", +"name":"ATP diphosphohydrolase", +"metabolites":{ +"adp_e":-1.0, +"amp_e":1.0, +"h2o_e":-1.0, +"h_e":1.0, +"pi_e":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"956_AT1 or 954_AT2 or 957_AT1 or 954_AT1 or 953_AT1 or 955_AT1", +"subsystem":"Nucleotides", +"notes":{ +"original_bigg_ids":[ +"ATPH2e" +] +} +}, +{ +"id":"ATPS4m", +"name":"ATP synthase (four protons for one ATP)", +"metabolites":{ +"adp_m":-1.0, +"atp_m":1.0, +"h2o_m":1.0, +"h_c":-4.0, +"h_m":3.0, +"pi_m":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"((522_AT2 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 517_AT1 and 521_AT1 and 515_AT2 and 10632_AT1) or (515_AT3 and 10476_AT1 and 516_AT2 and 4905_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 521_AT1) or (10476_AT1 and 518_AT2 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT3 and 515_AT2 and 521_AT1) or (522_AT5 and 4905_AT1 and 518_AT3 and 10476_AT1 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT1 and 515_AT3 and 10476_AT2 and 516_AT2 and 4905_AT1) or (522_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 10476_AT1 and 516_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 522_AT4 and 517_AT2) or (521_AT1 and 522_AT1 and 10632_AT1 and 516_AT2 and 4905_AT1 and 9551_AT3 and 515_AT3 and 10476_AT1) or (515_AT1 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT2) or (522_AT4 and 521_AT1 and 517_AT2 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT1 and 515_AT1) or (522_AT1 and 517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 515_AT3) or (521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 518_AT3 and 515_AT1 and 10476_AT2) or (10632_AT1 and 515_AT2 and 521_AT1 and 517_AT2 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 522_AT2) or (10476_AT1 and 515_AT1 and 522_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 517_AT1 and 521_AT1) or (4905_AT1 and 516_AT2 and 10476_AT2 and 521_AT1 and 515_AT2 and 9551_AT1 and 522_AT3 and 10632_AT1) or (10632_AT1 and 9551_AT1 and 518_AT1 and 521_AT1 and 10476_AT2 and 515_AT3 and 522_AT2 and 4905_AT1) or (9551_AT1 and 10632_AT1 and 522_AT3 and 521_AT1 and 517_AT2 and 10476_AT2 and 515_AT1 and 4905_AT1) or (10476_AT1 and 4905_AT1 and 516_AT2 and 10632_AT1 and 522_AT3 and 9551_AT1 and 521_AT1 and 515_AT2) or (10476_AT1 and 516_AT2 and 4905_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1) or (10632_AT1 and 522_AT4 and 515_AT2 and 521_AT1 and 518_AT3 and 10476_AT1 and 9551_AT3 and 4905_AT1) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 10476_AT2 and 518_AT2 and 515_AT3) or (515_AT3 and 10476_AT1 and 516_AT2 and 4905_AT1 and 522_AT5 and 9551_AT2 and 10632_AT1 and 521_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 522_AT1 and 517_AT2) or (521_AT1 and 515_AT2 and 518_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 10476_AT2) or (522_AT4 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 518_AT3 and 515_AT1) or (10476_AT2 and 516_AT1 and 515_AT3 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 521_AT1 and 522_AT4) or (522_AT5 and 4905_AT1 and 10476_AT2 and 518_AT1 and 521_AT1 and 515_AT2 and 9551_AT2 and 10632_AT1) or (515_AT2 and 521_AT1 and 518_AT1 and 522_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT2) or (521_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3 and 518_AT2 and 515_AT1 and 10476_AT2) or (9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 10476_AT1 and 515_AT1 and 518_AT3 and 4905_AT1) or (9551_AT2 and 10632_AT1 and 518_AT1 and 521_AT1 and 10476_AT2 and 515_AT3 and 522_AT2 and 4905_AT1) or (521_AT1 and 522_AT4 and 517_AT2 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2) or (521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2 and 518_AT3) or (4905_AT1 and 10476_AT2 and 518_AT2 and 515_AT3 and 521_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1) or (9551_AT3 and 4905_AT1 and 10476_AT2 and 515_AT1 and 518_AT2 and 522_AT1 and 521_AT1 and 10632_AT1) or (10632_AT1 and 521_AT1 and 515_AT2 and 522_AT4 and 518_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (515_AT2 and 521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 516_AT1 and 10476_AT1) or (517_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT1 and 522_AT5 and 4905_AT1 and 10476_AT1) or (517_AT2 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5 and 4905_AT1 and 10476_AT1) or (518_AT3 and 10476_AT2 and 4905_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 515_AT2 and 521_AT1) or (521_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 516_AT2 and 9551_AT3 and 10476_AT2 and 515_AT1) or (522_AT3 and 10632_AT1 and 521_AT1 and 10476_AT1 and 515_AT1 and 516_AT2 and 4905_AT1 and 9551_AT3) or (522_AT5 and 4905_AT1 and 10476_AT1 and 515_AT1 and 518_AT3 and 521_AT1 and 9551_AT1 and 10632_AT1) or (9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 517_AT2 and 515_AT1 and 10476_AT2 and 4905_AT1) or (10476_AT2 and 515_AT3 and 522_AT2 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 518_AT1 and 521_AT1) or (4905_AT1 and 9551_AT3 and 10476_AT1 and 515_AT2 and 521_AT1 and 517_AT2 and 522_AT3 and 10632_AT1) or (10476_AT2 and 9551_AT3 and 522_AT2 and 4905_AT1 and 10632_AT1 and 518_AT1 and 515_AT2 and 521_AT1) or (10476_AT1 and 515_AT3 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1 and 522_AT4) or (10632_AT1 and 9551_AT1 and 518_AT1 and 521_AT1 and 515_AT1 and 10476_AT1 and 522_AT5 and 4905_AT1) or (4905_AT1 and 522_AT5 and 10476_AT1 and 516_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT2) or (9551_AT3 and 4905_AT1 and 10476_AT1 and 515_AT3 and 518_AT2 and 522_AT1 and 521_AT1 and 10632_AT1) or (9551_AT2 and 10632_AT1 and 517_AT1 and 515_AT2 and 521_AT1 and 10476_AT2 and 4905_AT1 and 522_AT5) or (10476_AT1 and 515_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 517_AT2 and 521_AT1) or (4905_AT1 and 9551_AT3 and 515_AT3 and 10476_AT1 and 522_AT4 and 521_AT1 and 517_AT1 and 10632_AT1) or (10632_AT1 and 521_AT1 and 515_AT3 and 518_AT3 and 10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3) or (515_AT1 and 10476_AT2 and 9551_AT3 and 522_AT2 and 4905_AT1 and 10632_AT1 and 518_AT1 and 521_AT1) or (4905_AT1 and 522_AT5 and 516_AT1 and 10476_AT2 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT1 and 515_AT3 and 518_AT1 and 521_AT1 and 10632_AT1) or (521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 522_AT2 and 518_AT2 and 515_AT1 and 10476_AT2) or (515_AT3 and 518_AT2 and 10476_AT2 and 522_AT5 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 521_AT1) or (515_AT1 and 10476_AT1 and 9551_AT3 and 522_AT2 and 4905_AT1 and 10632_AT1 and 517_AT1 and 521_AT1) or (4905_AT1 and 522_AT2 and 9551_AT3 and 10476_AT1 and 515_AT2 and 521_AT1 and 517_AT1 and 10632_AT1) or (521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT5 and 4905_AT1 and 10476_AT2 and 515_AT1 and 516_AT1) or (9551_AT1 and 10632_AT1 and 522_AT3 and 521_AT1 and 518_AT1 and 515_AT1 and 10476_AT1 and 4905_AT1) or (515_AT1 and 10476_AT2 and 516_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT3 and 521_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 521_AT1 and 522_AT4 and 517_AT1 and 9551_AT1 and 10632_AT1) or (10476_AT1 and 516_AT1 and 4905_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT2) or (521_AT1 and 9551_AT1 and 10632_AT1 and 522_AT5 and 4905_AT1 and 515_AT1 and 10476_AT2 and 516_AT1) or (521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 522_AT5 and 516_AT1 and 10476_AT2 and 515_AT3) or (521_AT1 and 10632_AT1 and 522_AT3 and 9551_AT3 and 4905_AT1 and 518_AT3 and 10476_AT2 and 515_AT3) or (9551_AT2 and 10632_AT1 and 521_AT1 and 516_AT1 and 10476_AT2 and 515_AT3 and 522_AT2 and 4905_AT1) or (515_AT1 and 10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT1) or (521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT2 and 516_AT2 and 4905_AT1 and 10476_AT1 and 515_AT3) or (4905_AT1 and 516_AT2 and 515_AT3 and 10476_AT1 and 521_AT1 and 522_AT4 and 9551_AT1 and 10632_AT1) or (10476_AT1 and 515_AT1 and 9551_AT3 and 4905_AT1 and 516_AT2 and 10632_AT1 and 521_AT1 and 522_AT4) or (521_AT1 and 522_AT4 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 516_AT1 and 515_AT3) or (4905_AT1 and 518_AT2 and 10476_AT1 and 515_AT2 and 521_AT1 and 522_AT1 and 9551_AT2 and 10632_AT1) or (10632_AT1 and 521_AT1 and 522_AT4 and 518_AT1 and 515_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3) or (515_AT1 and 518_AT3 and 10476_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 521_AT1 and 522_AT4) or (522_AT4 and 521_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 10476_AT1 and 518_AT2 and 515_AT3) or (515_AT1 and 10476_AT2 and 4905_AT1 and 522_AT5 and 516_AT2 and 10632_AT1 and 9551_AT1 and 521_AT1) or (10632_AT1 and 9551_AT1 and 522_AT1 and 521_AT1 and 10476_AT2 and 515_AT1 and 516_AT1 and 4905_AT1) or (522_AT5 and 4905_AT1 and 9551_AT3 and 515_AT3 and 10476_AT2 and 521_AT1 and 517_AT2 and 10632_AT1) or (521_AT1 and 522_AT1 and 517_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT1 and 10476_AT2) or (9551_AT3 and 4905_AT1 and 10476_AT2 and 518_AT2 and 515_AT3 and 521_AT1 and 522_AT3 and 10632_AT1) or (515_AT3 and 518_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1) or (10476_AT2 and 518_AT2 and 515_AT3 and 9551_AT3 and 4905_AT1 and 522_AT5 and 10632_AT1 and 521_AT1) or (10632_AT1 and 521_AT1 and 517_AT2 and 515_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 522_AT2) or (4905_AT1 and 516_AT2 and 10476_AT1 and 515_AT1 and 521_AT1 and 522_AT4 and 10632_AT1 and 9551_AT1) or (10476_AT2 and 4905_AT1 and 516_AT2 and 522_AT2 and 10632_AT1 and 9551_AT2 and 521_AT1 and 515_AT2) or (521_AT1 and 517_AT2 and 522_AT3 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 515_AT3 and 10476_AT1) or (9551_AT2 and 10632_AT1 and 517_AT2 and 521_AT1 and 522_AT4 and 515_AT1 and 10476_AT2 and 4905_AT1) or (10476_AT2 and 522_AT5 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 517_AT1) or (518_AT1 and 521_AT1 and 522_AT3 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT1 and 515_AT1) or (521_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3 and 515_AT1 and 518_AT3 and 10476_AT2) or (10476_AT2 and 515_AT1 and 4905_AT1 and 9551_AT3 and 522_AT3 and 10632_AT1 and 521_AT1 and 517_AT2) or (9551_AT2 and 10632_AT1 and 521_AT1 and 515_AT3 and 10476_AT1 and 518_AT3 and 4905_AT1 and 522_AT2) or (4905_AT1 and 515_AT1 and 10476_AT1 and 518_AT1 and 522_AT4 and 521_AT1 and 10632_AT1 and 9551_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT4 and 521_AT1 and 518_AT1) or (10632_AT1 and 518_AT1 and 521_AT1 and 10476_AT1 and 515_AT3 and 522_AT2 and 9551_AT3 and 4905_AT1) or (9551_AT2 and 10632_AT1 and 517_AT1 and 515_AT2 and 521_AT1 and 10476_AT1 and 522_AT2 and 4905_AT1) or (4905_AT1 and 522_AT5 and 518_AT2 and 10476_AT2 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT2) or (9551_AT2 and 522_AT3 and 10632_AT1 and 515_AT2 and 521_AT1 and 10476_AT2 and 516_AT2 and 4905_AT1) or (515_AT3 and 10476_AT1 and 516_AT1 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1) or (522_AT1 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 516_AT1 and 10476_AT2) or (10476_AT1 and 4905_AT1 and 9551_AT3 and 522_AT3 and 10632_AT1 and 515_AT2 and 521_AT1 and 517_AT1) or (516_AT1 and 10476_AT1 and 515_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT3 and 521_AT1) or (521_AT1 and 517_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 522_AT5 and 515_AT1 and 10476_AT1) or (10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 518_AT1) or (10476_AT1 and 9551_AT3 and 4905_AT1 and 522_AT5 and 516_AT2 and 10632_AT1 and 521_AT1 and 515_AT2) or (521_AT1 and 10632_AT1 and 516_AT2 and 4905_AT1 and 522_AT2 and 9551_AT3 and 515_AT3 and 10476_AT1) or (9551_AT1 and 10632_AT1 and 522_AT3 and 515_AT2 and 521_AT1 and 518_AT2 and 10476_AT2 and 4905_AT1) or (10476_AT1 and 515_AT3 and 4905_AT1 and 522_AT5 and 10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1) or (522_AT4 and 521_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 518_AT2 and 515_AT3 and 10476_AT2) or (522_AT5 and 4905_AT1 and 518_AT3 and 10476_AT2 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1) or (10476_AT2 and 516_AT2 and 4905_AT1 and 522_AT2 and 9551_AT3 and 10632_AT1 and 515_AT2 and 521_AT1) or (522_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 516_AT2 and 515_AT1 and 10476_AT2) or (9551_AT2 and 10632_AT1 and 521_AT1 and 10476_AT1 and 515_AT3 and 518_AT2 and 522_AT5 and 4905_AT1) or (10632_AT1 and 521_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 522_AT2 and 4905_AT1) or (4905_AT1 and 10476_AT2 and 516_AT1 and 522_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT2) or (4905_AT1 and 515_AT1 and 10476_AT2 and 518_AT3 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT3 and 521_AT1 and 517_AT2) or (521_AT1 and 9551_AT1 and 10632_AT1 and 522_AT3 and 4905_AT1 and 515_AT3 and 10476_AT2 and 518_AT3) or (10632_AT1 and 518_AT1 and 521_AT1 and 515_AT2 and 10476_AT1 and 9551_AT3 and 4905_AT1 and 522_AT5) or (9551_AT3 and 522_AT2 and 4905_AT1 and 10476_AT2 and 515_AT3 and 518_AT2 and 521_AT1 and 10632_AT1) or (10632_AT1 and 521_AT1 and 522_AT1 and 516_AT1 and 515_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (517_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2) or (10632_AT1 and 9551_AT2 and 522_AT4 and 521_AT1 and 517_AT1 and 515_AT3 and 10476_AT2 and 4905_AT1) or (522_AT1 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT1 and 518_AT2) or (4905_AT1 and 522_AT2 and 518_AT2 and 515_AT3 and 10476_AT2 and 521_AT1 and 9551_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 9551_AT3 and 518_AT3 and 515_AT1 and 10476_AT2 and 521_AT1 and 10632_AT1) or (4905_AT1 and 515_AT3 and 10476_AT1 and 518_AT3 and 521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1) or (521_AT1 and 10632_AT1 and 522_AT2 and 9551_AT3 and 4905_AT1 and 516_AT2 and 10476_AT2 and 515_AT3) or (10632_AT1 and 9551_AT2 and 521_AT1 and 515_AT2 and 10476_AT1 and 516_AT1 and 4905_AT1 and 522_AT2) or (521_AT1 and 515_AT2 and 10632_AT1 and 522_AT2 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 516_AT1) or (521_AT1 and 522_AT4 and 518_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2) or (515_AT2 and 521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 518_AT3 and 10476_AT1) or (522_AT2 and 4905_AT1 and 10476_AT1 and 515_AT1 and 518_AT3 and 521_AT1 and 9551_AT2 and 10632_AT1) or (521_AT1 and 515_AT2 and 522_AT1 and 10632_AT1 and 4905_AT1 and 516_AT2 and 9551_AT3 and 10476_AT2) or (522_AT4 and 515_AT2 and 521_AT1 and 517_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 10476_AT2) or (10476_AT1 and 515_AT1 and 522_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1) or (9551_AT3 and 4905_AT1 and 10476_AT2 and 515_AT3 and 518_AT1 and 521_AT1 and 522_AT4 and 10632_AT1) or (10476_AT2 and 515_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 518_AT1 and 521_AT1) or (516_AT2 and 4905_AT1 and 10476_AT2 and 515_AT2 and 521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1) or (10476_AT2 and 518_AT2 and 4905_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1) or (10476_AT1 and 4905_AT1 and 522_AT5 and 10632_AT1 and 9551_AT2 and 517_AT2 and 515_AT2 and 521_AT1) or (4905_AT1 and 522_AT2 and 9551_AT3 and 515_AT3 and 10476_AT2 and 521_AT1 and 517_AT2 and 10632_AT1) or (518_AT1 and 521_AT1 and 515_AT2 and 9551_AT2 and 10632_AT1 and 522_AT2 and 4905_AT1 and 10476_AT1) or (516_AT1 and 10476_AT2 and 515_AT1 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT4 and 521_AT1) or (10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 517_AT1 and 521_AT1 and 522_AT4 and 515_AT2) or (521_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 515_AT3 and 518_AT2 and 10476_AT1) or (10476_AT1 and 9551_AT3 and 4905_AT1 and 516_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT2) or (9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT2 and 515_AT3 and 517_AT1 and 521_AT1 and 10632_AT1) or (522_AT2 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (518_AT1 and 521_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 4905_AT1 and 515_AT1 and 10476_AT1) or (521_AT1 and 515_AT2 and 10632_AT1 and 4905_AT1 and 522_AT2 and 9551_AT3 and 518_AT3 and 10476_AT2) or (10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1 and 518_AT1 and 522_AT1) or (4905_AT1 and 515_AT1 and 10476_AT1 and 518_AT3 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1) or (10476_AT2 and 515_AT1 and 522_AT2 and 4905_AT1 and 516_AT2 and 10632_AT1 and 9551_AT1 and 521_AT1) or (9551_AT2 and 10632_AT1 and 517_AT2 and 522_AT4 and 515_AT2 and 521_AT1 and 10476_AT2 and 4905_AT1) or (522_AT5 and 4905_AT1 and 518_AT3 and 10476_AT2 and 515_AT1 and 521_AT1 and 9551_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 518_AT3 and 10476_AT2 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 10476_AT1 and 518_AT3 and 515_AT3 and 521_AT1 and 522_AT4 and 10632_AT1 and 9551_AT1) or (10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1 and 515_AT2 and 10476_AT1 and 522_AT2 and 4905_AT1) or (10632_AT1 and 9551_AT2 and 522_AT4 and 515_AT2 and 521_AT1 and 516_AT1 and 10476_AT2 and 4905_AT1) or (10476_AT1 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT3 and 518_AT1 and 515_AT2 and 521_AT1) or (521_AT1 and 517_AT2 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 522_AT2 and 515_AT1 and 10476_AT1) or (9551_AT2 and 522_AT3 and 10632_AT1 and 517_AT2 and 521_AT1 and 10476_AT2 and 515_AT3 and 4905_AT1) or (10476_AT2 and 515_AT1 and 518_AT3 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT1 and 521_AT1) or (521_AT1 and 515_AT2 and 10632_AT1 and 522_AT5 and 4905_AT1 and 516_AT2 and 9551_AT3 and 10476_AT2) or (521_AT1 and 518_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT1) or (4905_AT1 and 518_AT2 and 515_AT1 and 10476_AT1 and 521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT1 and 518_AT3 and 521_AT1 and 9551_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT1 and 521_AT1 and 518_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 517_AT1 and 522_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT2 and 10632_AT1 and 521_AT1 and 518_AT1) or (10632_AT1 and 522_AT4 and 521_AT1 and 10476_AT1 and 518_AT3 and 515_AT3 and 9551_AT3 and 4905_AT1) or (522_AT5 and 4905_AT1 and 10476_AT2 and 517_AT2 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3 and 522_AT4 and 521_AT1 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 522_AT1 and 517_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2) or (10632_AT1 and 521_AT1 and 522_AT4 and 518_AT2 and 515_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (10476_AT1 and 518_AT2 and 4905_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1) or (10632_AT1 and 521_AT1 and 10476_AT2 and 518_AT3 and 515_AT3 and 522_AT2 and 9551_AT3 and 4905_AT1) or (518_AT2 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1) or (10632_AT1 and 521_AT1 and 10476_AT2 and 518_AT3 and 515_AT3 and 9551_AT3 and 4905_AT1 and 522_AT5) or (10476_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT1 and 518_AT1 and 521_AT1 and 515_AT2) or (4905_AT1 and 10476_AT1 and 518_AT3 and 515_AT3 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 522_AT1 and 517_AT2 and 9551_AT1 and 10632_AT1) or (522_AT5 and 4905_AT1 and 516_AT2 and 10476_AT2 and 521_AT1 and 515_AT2 and 9551_AT1 and 10632_AT1) or (4905_AT1 and 522_AT5 and 10476_AT1 and 515_AT3 and 518_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1) or (10476_AT2 and 515_AT3 and 9551_AT3 and 522_AT2 and 4905_AT1 and 10632_AT1 and 517_AT1 and 521_AT1) or (4905_AT1 and 522_AT2 and 9551_AT3 and 10476_AT1 and 521_AT1 and 515_AT2 and 517_AT2 and 10632_AT1) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 515_AT1 and 10476_AT1 and 518_AT3) or (4905_AT1 and 9551_AT3 and 515_AT1 and 10476_AT2 and 521_AT1 and 517_AT2 and 522_AT1 and 10632_AT1) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 516_AT2 and 10476_AT2 and 515_AT1) or (4905_AT1 and 516_AT1 and 10476_AT2 and 522_AT4 and 515_AT2 and 521_AT1 and 9551_AT1 and 10632_AT1) or (515_AT2 and 522_AT4 and 521_AT1 and 9551_AT1 and 10632_AT1 and 516_AT2 and 4905_AT1 and 10476_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT1 and 515_AT3 and 10476_AT1 and 4905_AT1 and 522_AT2) or (517_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT2 and 4905_AT1 and 10476_AT2 and 515_AT1) or (521_AT1 and 515_AT2 and 522_AT1 and 517_AT2 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT2) or (9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 10476_AT1 and 4905_AT1 and 522_AT5 and 516_AT2) or (4905_AT1 and 518_AT3 and 10476_AT2 and 515_AT3 and 522_AT4 and 521_AT1 and 10632_AT1 and 9551_AT1) or (521_AT1 and 517_AT2 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 522_AT5 and 515_AT3 and 10476_AT2) or (521_AT1 and 522_AT4 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT2 and 516_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 518_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 10476_AT1 and 518_AT2 and 521_AT1 and 522_AT4 and 515_AT2 and 9551_AT2 and 10632_AT1) or (521_AT1 and 515_AT2 and 10632_AT1 and 522_AT3 and 4905_AT1 and 9551_AT3 and 518_AT3 and 10476_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 10476_AT2 and 4905_AT1 and 516_AT2 and 522_AT2) or (515_AT1 and 10476_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 522_AT1 and 517_AT1 and 521_AT1) or (10632_AT1 and 522_AT1 and 515_AT2 and 521_AT1 and 10476_AT2 and 518_AT2 and 9551_AT3 and 4905_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 522_AT1 and 517_AT1) or (4905_AT1 and 516_AT2 and 10476_AT1 and 521_AT1 and 515_AT2 and 522_AT1 and 9551_AT2 and 10632_AT1) or (518_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 522_AT4 and 515_AT2 and 521_AT1) or (521_AT1 and 522_AT4 and 515_AT2 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 516_AT2 and 10476_AT2) or (9551_AT3 and 4905_AT1 and 10476_AT1 and 516_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 522_AT3) or (9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT2 and 518_AT1 and 521_AT1 and 515_AT2 and 10632_AT1) or (9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT1 and 517_AT1 and 515_AT2 and 521_AT1 and 10632_AT1) or (515_AT1 and 10476_AT1 and 522_AT5 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 517_AT2 and 521_AT1) or (516_AT1 and 10476_AT2 and 4905_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 515_AT2 and 521_AT1) or (4905_AT1 and 9551_AT3 and 10476_AT2 and 521_AT1 and 515_AT2 and 517_AT2 and 522_AT3 and 10632_AT1) or (521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT1 and 522_AT2 and 4905_AT1 and 10476_AT2 and 516_AT1) or (518_AT2 and 515_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT2 and 10476_AT2 and 515_AT1 and 4905_AT1 and 522_AT2) or (521_AT1 and 517_AT1 and 9551_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT1) or (9551_AT3 and 4905_AT1 and 515_AT1 and 10476_AT2 and 518_AT2 and 522_AT4 and 521_AT1 and 10632_AT1) or (522_AT4 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 518_AT3 and 10476_AT2) or (516_AT1 and 10476_AT2 and 4905_AT1 and 522_AT5 and 9551_AT1 and 10632_AT1 and 515_AT2 and 521_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT3 and 521_AT1 and 517_AT1) or (515_AT3 and 518_AT2 and 10476_AT1 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT1) or (10476_AT1 and 515_AT1 and 4905_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1 and 517_AT1 and 521_AT1) or (10632_AT1 and 515_AT2 and 521_AT1 and 516_AT1 and 10476_AT2 and 522_AT5 and 4905_AT1 and 9551_AT3) or (521_AT1 and 10632_AT1 and 522_AT2 and 9551_AT3 and 4905_AT1 and 516_AT1 and 515_AT1 and 10476_AT2) or (10632_AT1 and 521_AT1 and 517_AT1 and 515_AT3 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT3) or (9551_AT2 and 10632_AT1 and 517_AT1 and 521_AT1 and 10476_AT2 and 515_AT1 and 4905_AT1 and 522_AT5) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT1) or (10476_AT1 and 515_AT1 and 518_AT3 and 4905_AT1 and 522_AT5 and 9551_AT2 and 10632_AT1 and 521_AT1) or (515_AT3 and 516_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT4 and 521_AT1) or (10632_AT1 and 522_AT1 and 521_AT1 and 10476_AT1 and 515_AT1 and 518_AT2 and 9551_AT3 and 4905_AT1) or (522_AT3 and 10632_AT1 and 521_AT1 and 515_AT2 and 10476_AT2 and 518_AT2 and 9551_AT3 and 4905_AT1) or (10632_AT1 and 9551_AT2 and 522_AT3 and 517_AT2 and 521_AT1 and 10476_AT1 and 515_AT3 and 4905_AT1) or (521_AT1 and 10632_AT1 and 9551_AT1 and 522_AT5 and 4905_AT1 and 10476_AT2 and 515_AT3 and 518_AT2) or (10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1 and 522_AT4 and 10476_AT1 and 515_AT1 and 4905_AT1) or (518_AT3 and 10476_AT2 and 515_AT3 and 4905_AT1 and 522_AT5 and 10632_AT1 and 9551_AT1 and 521_AT1) or (4905_AT1 and 10476_AT1 and 515_AT3 and 517_AT1 and 522_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1) or (521_AT1 and 9551_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 515_AT3 and 516_AT1 and 10476_AT2) or (10476_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT1 and 518_AT1 and 521_AT1 and 515_AT2) or (4905_AT1 and 515_AT3 and 10476_AT1 and 521_AT1 and 517_AT2 and 522_AT1 and 9551_AT2 and 10632_AT1) or (9551_AT3 and 4905_AT1 and 516_AT1 and 515_AT1 and 10476_AT1 and 522_AT4 and 521_AT1 and 10632_AT1) or (521_AT1 and 517_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT1) or (521_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 516_AT2 and 4905_AT1 and 10476_AT2 and 515_AT3) or (10632_AT1 and 521_AT1 and 522_AT4 and 10476_AT1 and 518_AT3 and 515_AT1 and 4905_AT1 and 9551_AT3) or (10476_AT2 and 518_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT1 and 515_AT2 and 521_AT1) or (10632_AT1 and 522_AT3 and 9551_AT1 and 517_AT1 and 521_AT1 and 515_AT2 and 10476_AT2 and 4905_AT1) or (521_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1 and 4905_AT1 and 10476_AT1 and 516_AT1 and 515_AT3) or (9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT2 and 517_AT2 and 10476_AT2 and 4905_AT1) or (515_AT2 and 521_AT1 and 517_AT2 and 9551_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1) or (10476_AT2 and 515_AT3 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 517_AT1 and 522_AT4 and 521_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 516_AT2 and 9551_AT1 and 522_AT3 and 10632_AT1 and 521_AT1) or (521_AT1 and 10632_AT1 and 4905_AT1 and 522_AT2 and 9551_AT3 and 516_AT1 and 10476_AT1 and 515_AT1) or (9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1 and 515_AT3 and 518_AT3 and 10476_AT1 and 4905_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1 and 517_AT1) or (521_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 518_AT3 and 10476_AT2 and 515_AT1) or (10632_AT1 and 9551_AT1 and 521_AT1 and 522_AT4 and 10476_AT1 and 515_AT1 and 518_AT2 and 4905_AT1) or (515_AT3 and 10476_AT2 and 522_AT5 and 4905_AT1 and 516_AT2 and 9551_AT3 and 10632_AT1 and 521_AT1) or (9551_AT2 and 10632_AT1 and 522_AT1 and 517_AT2 and 521_AT1 and 10476_AT2 and 515_AT3 and 4905_AT1) or (9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT4 and 515_AT1 and 10476_AT1 and 4905_AT1 and 516_AT2) or (521_AT1 and 517_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 515_AT3 and 10476_AT2) or (517_AT1 and 522_AT1 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 10476_AT1) or (521_AT1 and 10632_AT1 and 9551_AT1 and 522_AT2 and 4905_AT1 and 10476_AT1 and 515_AT1 and 518_AT2) or (10476_AT2 and 515_AT1 and 4905_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1 and 517_AT1 and 521_AT1) or (521_AT1 and 522_AT1 and 518_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 515_AT3 and 10476_AT1) or (10476_AT2 and 515_AT1 and 9551_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 517_AT1 and 521_AT1) or (10632_AT1 and 9551_AT1 and 517_AT2 and 522_AT1 and 515_AT2 and 521_AT1 and 10476_AT2 and 4905_AT1) or (521_AT1 and 515_AT2 and 517_AT2 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 10476_AT1) or (4905_AT1 and 515_AT1 and 10476_AT1 and 517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3) or (4905_AT1 and 516_AT2 and 9551_AT3 and 522_AT2 and 10476_AT1 and 521_AT1 and 515_AT2 and 10632_AT1) or (522_AT5 and 4905_AT1 and 10476_AT1 and 518_AT1 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2) or (517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5 and 4905_AT1 and 515_AT1 and 10476_AT2) or (4905_AT1 and 522_AT2 and 518_AT3 and 515_AT1 and 10476_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (10476_AT2 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 515_AT2 and 521_AT1 and 518_AT1) or (521_AT1 and 522_AT4 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 516_AT2 and 10476_AT2 and 515_AT1) or (4905_AT1 and 10476_AT1 and 517_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT2 and 522_AT3) or (522_AT3 and 10632_AT1 and 521_AT1 and 515_AT2 and 518_AT3 and 10476_AT2 and 9551_AT3 and 4905_AT1) or (516_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 521_AT1) or (4905_AT1 and 515_AT1 and 10476_AT1 and 518_AT3 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2) or (10476_AT1 and 516_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 515_AT2 and 522_AT4 and 521_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 522_AT4 and 521_AT1 and 518_AT1) or (522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 515_AT3 and 518_AT3 and 10476_AT2) or (515_AT1 and 10476_AT1 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT1 and 518_AT1 and 521_AT1) or (4905_AT1 and 518_AT3 and 10476_AT1 and 521_AT1 and 515_AT2 and 9551_AT2 and 522_AT3 and 10632_AT1) or (10476_AT2 and 4905_AT1 and 522_AT5 and 10632_AT1 and 9551_AT2 and 517_AT2 and 515_AT2 and 521_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 516_AT2 and 10632_AT1 and 9551_AT2 and 521_AT1 and 522_AT4) or (4905_AT1 and 515_AT3 and 10476_AT2 and 518_AT3 and 521_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1) or (9551_AT2 and 10632_AT1 and 518_AT1 and 522_AT1 and 521_AT1 and 10476_AT2 and 515_AT3 and 4905_AT1) or (522_AT3 and 10632_AT1 and 515_AT2 and 521_AT1 and 518_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3) or (521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT3 and 516_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2) or (515_AT3 and 10476_AT1 and 4905_AT1 and 516_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT1) or (518_AT2 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2) or (10476_AT2 and 515_AT1 and 522_AT2 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 517_AT1 and 521_AT1) or (9551_AT2 and 10632_AT1 and 521_AT1 and 517_AT1 and 515_AT3 and 10476_AT2 and 522_AT5 and 4905_AT1) or (521_AT1 and 515_AT2 and 518_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT2 and 10476_AT1) or (9551_AT2 and 10632_AT1 and 522_AT3 and 518_AT1 and 521_AT1 and 515_AT2 and 10476_AT1 and 4905_AT1) or (521_AT1 and 9551_AT1 and 10632_AT1 and 522_AT3 and 516_AT2 and 4905_AT1 and 10476_AT1 and 515_AT1) or (10476_AT2 and 515_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 518_AT1 and 522_AT4 and 521_AT1) or (10476_AT1 and 515_AT3 and 522_AT2 and 516_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 521_AT1) or (521_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT1 and 516_AT1) or (515_AT1 and 10476_AT1 and 518_AT2 and 9551_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 521_AT1) or (521_AT1 and 515_AT2 and 522_AT3 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 10476_AT1 and 516_AT1) or (522_AT4 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1) or (521_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 515_AT1 and 10476_AT2 and 518_AT3) or (521_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 518_AT2 and 515_AT1 and 10476_AT1) or (10476_AT1 and 515_AT1 and 518_AT2 and 4905_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1 and 521_AT1) or (516_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT3 and 515_AT2 and 521_AT1) or (4905_AT1 and 522_AT2 and 516_AT1 and 515_AT1 and 10476_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (521_AT1 and 515_AT2 and 10632_AT1 and 522_AT3 and 4905_AT1 and 516_AT2 and 9551_AT3 and 10476_AT2) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3) or (10632_AT1 and 9551_AT2 and 515_AT2 and 521_AT1 and 517_AT1 and 10476_AT2 and 4905_AT1 and 522_AT2) or (521_AT1 and 515_AT2 and 9551_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT1 and 518_AT3) or (4905_AT1 and 10476_AT1 and 521_AT1 and 515_AT2 and 517_AT1 and 9551_AT1 and 522_AT3 and 10632_AT1) or (10632_AT1 and 522_AT1 and 517_AT2 and 521_AT1 and 515_AT1 and 10476_AT1 and 9551_AT3 and 4905_AT1) or (521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT2 and 4905_AT1 and 516_AT1 and 515_AT1 and 10476_AT1) or (9551_AT1 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT3 and 10476_AT1 and 516_AT2 and 4905_AT1) or (10632_AT1 and 522_AT3 and 517_AT1 and 521_AT1 and 10476_AT2 and 515_AT3 and 9551_AT3 and 4905_AT1) or (515_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 517_AT2 and 521_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 517_AT2 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT2 and 521_AT1 and 517_AT1 and 9551_AT1 and 10632_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT4 and 515_AT2 and 517_AT2 and 10476_AT1 and 4905_AT1) or (10476_AT2 and 4905_AT1 and 522_AT2 and 10632_AT1 and 9551_AT2 and 521_AT1 and 515_AT2 and 518_AT1) or (517_AT1 and 521_AT1 and 515_AT2 and 522_AT3 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2) or (515_AT1 and 10476_AT1 and 516_AT2 and 4905_AT1 and 522_AT5 and 9551_AT3 and 10632_AT1 and 521_AT1) or (515_AT2 and 521_AT1 and 517_AT1 and 522_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT2) or (521_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 518_AT3 and 10476_AT1 and 515_AT3) or (10476_AT1 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 517_AT2 and 521_AT1 and 515_AT2 and 522_AT4) or (522_AT3 and 10632_AT1 and 521_AT1 and 10476_AT2 and 515_AT3 and 9551_AT3 and 4905_AT1 and 516_AT2) or (521_AT1 and 515_AT2 and 522_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 10476_AT1 and 518_AT3) or (9551_AT1 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT2 and 518_AT1 and 10476_AT1 and 4905_AT1) or (4905_AT1 and 518_AT3 and 10476_AT2 and 521_AT1 and 515_AT2 and 9551_AT2 and 10632_AT1 and 522_AT3) or (517_AT2 and 522_AT4 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2) or (517_AT2 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 515_AT1 and 10476_AT1) or (10476_AT2 and 515_AT1 and 516_AT2 and 4905_AT1 and 522_AT2 and 9551_AT2 and 10632_AT1 and 521_AT1) or (518_AT2 and 10476_AT1 and 515_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3 and 10632_AT1 and 521_AT1) or (518_AT1 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2) or (521_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 522_AT2 and 515_AT3 and 518_AT2 and 10476_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 517_AT1 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 522_AT2 and 10476_AT2 and 515_AT2 and 521_AT1 and 517_AT2 and 9551_AT1 and 10632_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 522_AT5 and 9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT2) or (521_AT1 and 515_AT2 and 522_AT4 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT2 and 516_AT1) or (515_AT1 and 10476_AT1 and 522_AT5 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 518_AT1 and 521_AT1) or (521_AT1 and 10632_AT1 and 9551_AT2 and 522_AT5 and 4905_AT1 and 516_AT2 and 10476_AT1 and 515_AT1) or (522_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 516_AT2 and 10476_AT1) or (10476_AT2 and 515_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 517_AT2 and 521_AT1) or (521_AT1 and 522_AT4 and 517_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT1) or (522_AT2 and 9551_AT3 and 4905_AT1 and 515_AT1 and 10476_AT2 and 518_AT2 and 521_AT1 and 10632_AT1) or (9551_AT3 and 4905_AT1 and 516_AT1 and 10476_AT2 and 515_AT1 and 522_AT1 and 521_AT1 and 10632_AT1) or (9551_AT3 and 4905_AT1 and 10476_AT1 and 518_AT2 and 521_AT1 and 522_AT4 and 515_AT2 and 10632_AT1) or (9551_AT3 and 516_AT2 and 4905_AT1 and 515_AT1 and 10476_AT1 and 522_AT1 and 521_AT1 and 10632_AT1) or (521_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 4905_AT1 and 515_AT3 and 516_AT1 and 10476_AT1) or (522_AT5 and 4905_AT1 and 515_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 9551_AT1 and 10632_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT4 and 521_AT1 and 517_AT2) or (4905_AT1 and 10476_AT2 and 518_AT3 and 521_AT1 and 515_AT2 and 522_AT1 and 9551_AT2 and 10632_AT1) or (521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 516_AT2 and 522_AT2 and 10476_AT1 and 515_AT1) or (522_AT3 and 10632_AT1 and 9551_AT1 and 517_AT2 and 515_AT2 and 521_AT1 and 10476_AT2 and 4905_AT1) or (9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT2 and 515_AT1 and 516_AT1 and 521_AT1 and 10632_AT1) or (522_AT3 and 10632_AT1 and 521_AT1 and 518_AT1 and 515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2 and 522_AT2 and 4905_AT1 and 10476_AT2 and 515_AT3) or (10476_AT1 and 515_AT3 and 516_AT2 and 522_AT5 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 521_AT1) or (10632_AT1 and 522_AT3 and 521_AT1 and 518_AT1 and 515_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3) or (10476_AT1 and 515_AT3 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 518_AT1 and 522_AT1 and 521_AT1) or (10632_AT1 and 515_AT2 and 521_AT1 and 518_AT1 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT3) or (4905_AT1 and 518_AT2 and 10476_AT2 and 515_AT1 and 521_AT1 and 522_AT4 and 10632_AT1 and 9551_AT2) or (521_AT1 and 517_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT3 and 10476_AT1) or (515_AT3 and 518_AT2 and 10476_AT1 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 522_AT3 and 521_AT1) or (522_AT5 and 4905_AT1 and 516_AT2 and 10476_AT2 and 515_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1) or (521_AT1 and 518_AT1 and 522_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT1 and 10476_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 518_AT3 and 10476_AT1 and 4905_AT1 and 522_AT5) or (10476_AT2 and 515_AT3 and 516_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT4 and 521_AT1) or (515_AT3 and 518_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 522_AT1) or (10476_AT2 and 515_AT1 and 522_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 518_AT1 and 521_AT1) or (521_AT1 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 522_AT5 and 516_AT2 and 10476_AT2 and 515_AT3) or (522_AT5 and 4905_AT1 and 9551_AT3 and 10476_AT2 and 515_AT2 and 521_AT1 and 517_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 518_AT2 and 10476_AT2 and 521_AT1 and 515_AT2 and 9551_AT2 and 10632_AT1) or (515_AT3 and 10476_AT2 and 522_AT5 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 521_AT1 and 518_AT1) or (518_AT3 and 10476_AT2 and 515_AT3 and 522_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 521_AT1) or (4905_AT1 and 10476_AT1 and 515_AT1 and 522_AT1 and 517_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1) or (9551_AT1 and 10632_AT1 and 522_AT4 and 515_AT2 and 521_AT1 and 10476_AT2 and 516_AT2 and 4905_AT1) or (9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1 and 515_AT3 and 518_AT2 and 10476_AT2 and 4905_AT1) or (10476_AT2 and 518_AT3 and 4905_AT1 and 522_AT5 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1) or (518_AT1 and 521_AT1 and 522_AT3 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 515_AT3) or (10476_AT1 and 515_AT3 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT1 and 517_AT2 and 521_AT1) or (4905_AT1 and 10476_AT1 and 515_AT1 and 521_AT1 and 522_AT4 and 518_AT1 and 9551_AT2 and 10632_AT1) or (522_AT3 and 10632_AT1 and 521_AT1 and 517_AT1 and 515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (515_AT3 and 10476_AT1 and 4905_AT1 and 516_AT2 and 9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1) or (4905_AT1 and 10476_AT2 and 515_AT2 and 521_AT1 and 517_AT1 and 522_AT1 and 10632_AT1 and 9551_AT2) or (10476_AT2 and 518_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 521_AT1 and 522_AT4 and 515_AT2) or (10632_AT1 and 9551_AT2 and 522_AT4 and 521_AT1 and 518_AT1 and 515_AT3 and 10476_AT2 and 4905_AT1) or (4905_AT1 and 522_AT2 and 9551_AT3 and 518_AT2 and 10476_AT1 and 515_AT1 and 521_AT1 and 10632_AT1) or (515_AT2 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 518_AT3 and 10476_AT2) or (4905_AT1 and 10476_AT1 and 515_AT1 and 517_AT1 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 10476_AT2 and 515_AT1 and 518_AT1 and 521_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1) or (522_AT2 and 9551_AT3 and 4905_AT1 and 518_AT3 and 10476_AT1 and 515_AT2 and 521_AT1 and 10632_AT1) or (518_AT1 and 521_AT1 and 515_AT2 and 522_AT4 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 10476_AT2) or (522_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2 and 518_AT3 and 521_AT1 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 522_AT5 and 10476_AT1 and 516_AT1 and 515_AT3 and 521_AT1 and 9551_AT2 and 10632_AT1) or (515_AT2 and 521_AT1 and 517_AT1 and 522_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT1) or (9551_AT3 and 4905_AT1 and 518_AT3 and 10476_AT2 and 515_AT3 and 522_AT1 and 521_AT1 and 10632_AT1) or (10632_AT1 and 521_AT1 and 517_AT1 and 515_AT3 and 10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3) or (521_AT1 and 522_AT3 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 518_AT3 and 10476_AT1 and 515_AT3) or (521_AT1 and 515_AT2 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 522_AT5 and 516_AT2 and 10476_AT2) or (10476_AT1 and 515_AT1 and 518_AT3 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 522_AT4 and 521_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT2) or (4905_AT1 and 10476_AT1 and 517_AT1 and 522_AT1 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1) or (10476_AT2 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 522_AT1 and 517_AT1) or (4905_AT1 and 515_AT3 and 10476_AT1 and 521_AT1 and 518_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 9551_AT3 and 518_AT2 and 515_AT1 and 10476_AT2 and 521_AT1 and 522_AT3 and 10632_AT1) or (4905_AT1 and 10476_AT2 and 515_AT3 and 517_AT1 and 521_AT1 and 522_AT4 and 10632_AT1 and 9551_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT1 and 10632_AT1 and 521_AT1 and 517_AT2) or (9551_AT2 and 10632_AT1 and 517_AT1 and 522_AT4 and 521_AT1 and 515_AT1 and 10476_AT1 and 4905_AT1) or (10632_AT1 and 521_AT1 and 518_AT1 and 515_AT3 and 10476_AT2 and 4905_AT1 and 522_AT5 and 9551_AT3) or (10632_AT1 and 521_AT1 and 10476_AT2 and 515_AT1 and 516_AT2 and 4905_AT1 and 522_AT2 and 9551_AT3) or (10476_AT2 and 518_AT3 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 515_AT2 and 522_AT1) or (10476_AT2 and 522_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 517_AT2 and 521_AT1 and 515_AT2) or (515_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 517_AT2 and 522_AT1 and 521_AT1) or (10476_AT2 and 515_AT1 and 516_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3 and 521_AT1) or (10632_AT1 and 522_AT4 and 521_AT1 and 515_AT3 and 518_AT2 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (518_AT2 and 10476_AT2 and 515_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 522_AT3 and 521_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT1 and 515_AT1 and 10476_AT2 and 4905_AT1 and 516_AT2) or (521_AT1 and 10632_AT1 and 522_AT3 and 4905_AT1 and 516_AT2 and 9551_AT3 and 515_AT3 and 10476_AT1) or (518_AT3 and 10476_AT1 and 522_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 521_AT1 and 515_AT2) or (522_AT5 and 4905_AT1 and 10476_AT1 and 515_AT3 and 517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2) or (518_AT1 and 522_AT4 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2) or (522_AT1 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 516_AT1 and 10476_AT1) or (516_AT2 and 4905_AT1 and 9551_AT3 and 515_AT1 and 10476_AT2 and 521_AT1 and 10632_AT1 and 522_AT3) or (10476_AT2 and 518_AT2 and 9551_AT3 and 4905_AT1 and 522_AT5 and 10632_AT1 and 515_AT2 and 521_AT1) or (10476_AT1 and 516_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 515_AT2 and 521_AT1 and 522_AT1) or (10632_AT1 and 517_AT1 and 522_AT4 and 515_AT2 and 521_AT1 and 10476_AT1 and 9551_AT3 and 4905_AT1) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT3) or (10632_AT1 and 521_AT1 and 515_AT2 and 522_AT4 and 10476_AT1 and 516_AT1 and 9551_AT3 and 4905_AT1) or (9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1 and 518_AT2 and 10476_AT1 and 4905_AT1 and 522_AT5) or (10476_AT1 and 515_AT3 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 517_AT2 and 522_AT4 and 521_AT1) or (4905_AT1 and 518_AT2 and 10476_AT2 and 515_AT1 and 521_AT1 and 9551_AT1 and 10632_AT1 and 522_AT3) or (516_AT2 and 4905_AT1 and 515_AT3 and 10476_AT2 and 521_AT1 and 522_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 522_AT5 and 9551_AT3 and 518_AT2 and 10476_AT1 and 515_AT2 and 521_AT1 and 10632_AT1) or (516_AT2 and 4905_AT1 and 10476_AT2 and 522_AT4 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 522_AT5 and 10476_AT2 and 515_AT1 and 521_AT1 and 517_AT2 and 9551_AT1 and 10632_AT1) or (515_AT3 and 516_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1) or (9551_AT1 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT1 and 10476_AT1 and 518_AT3 and 4905_AT1) or (522_AT1 and 518_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 515_AT3) or (521_AT1 and 515_AT2 and 518_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT2) or (521_AT1 and 10632_AT1 and 9551_AT1 and 4905_AT1 and 522_AT5 and 10476_AT2 and 515_AT1 and 518_AT2) or (10632_AT1 and 9551_AT1 and 517_AT2 and 522_AT4 and 521_AT1 and 10476_AT1 and 515_AT1 and 4905_AT1) or (521_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1 and 516_AT2 and 4905_AT1 and 10476_AT2 and 515_AT1) or (517_AT1 and 522_AT4 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 515_AT1 and 10476_AT1) or (521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT2 and 515_AT1 and 518_AT3 and 10476_AT1) or (10632_AT1 and 9551_AT1 and 518_AT1 and 521_AT1 and 10476_AT1 and 515_AT1 and 522_AT2 and 4905_AT1) or (10632_AT1 and 9551_AT1 and 522_AT4 and 521_AT1 and 515_AT1 and 10476_AT2 and 516_AT2 and 4905_AT1) or (522_AT3 and 10632_AT1 and 517_AT2 and 521_AT1 and 10476_AT1 and 515_AT1 and 9551_AT3 and 4905_AT1) or (10476_AT1 and 515_AT3 and 4905_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1 and 518_AT1 and 521_AT1) or (4905_AT1 and 522_AT5 and 515_AT3 and 10476_AT2 and 521_AT1 and 518_AT1 and 9551_AT1 and 10632_AT1) or (10476_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 518_AT1 and 515_AT2 and 522_AT4 and 521_AT1) or (517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 522_AT5 and 515_AT1 and 10476_AT1) or (515_AT1 and 10476_AT2 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 518_AT1 and 522_AT1 and 521_AT1) or (9551_AT3 and 4905_AT1 and 10476_AT2 and 517_AT1 and 521_AT1 and 522_AT4 and 515_AT2 and 10632_AT1) or (10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1 and 517_AT2) or (518_AT1 and 521_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 4905_AT1 and 10476_AT2 and 515_AT3) or (522_AT3 and 10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1 and 10476_AT2 and 515_AT3 and 4905_AT1) or (522_AT4 and 521_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 515_AT3 and 518_AT3 and 10476_AT2) or (10476_AT1 and 515_AT3 and 518_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 521_AT1 and 522_AT4) or (521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT2 and 516_AT1) or (10632_AT1 and 517_AT1 and 522_AT4 and 521_AT1 and 10476_AT2 and 515_AT1 and 9551_AT3 and 4905_AT1) or (10632_AT1 and 522_AT4 and 521_AT1 and 10476_AT1 and 515_AT3 and 9551_AT3 and 516_AT2 and 4905_AT1) or (9551_AT2 and 10632_AT1 and 515_AT2 and 521_AT1 and 518_AT3 and 10476_AT1 and 522_AT2 and 4905_AT1) or (9551_AT1 and 10632_AT1 and 515_AT2 and 521_AT1 and 522_AT1 and 518_AT2 and 10476_AT1 and 4905_AT1) or (9551_AT1 and 10632_AT1 and 515_AT2 and 522_AT4 and 521_AT1 and 517_AT1 and 10476_AT2 and 4905_AT1) or (10476_AT2 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 522_AT4 and 515_AT2 and 521_AT1 and 517_AT2) or (4905_AT1 and 522_AT5 and 10476_AT2 and 515_AT1 and 521_AT1 and 517_AT2 and 9551_AT2 and 10632_AT1) or (518_AT2 and 515_AT1 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT2 and 10632_AT1 and 521_AT1) or (10632_AT1 and 9551_AT2 and 515_AT2 and 521_AT1 and 516_AT1 and 10476_AT2 and 522_AT2 and 4905_AT1) or (521_AT1 and 522_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 518_AT2 and 10476_AT1 and 515_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT3 and 518_AT2 and 10476_AT1 and 4905_AT1 and 522_AT2) or (515_AT1 and 10476_AT1 and 522_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 518_AT1 and 521_AT1) or (4905_AT1 and 10476_AT2 and 518_AT2 and 515_AT3 and 521_AT1 and 522_AT4 and 9551_AT2 and 10632_AT1) or (516_AT2 and 4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (9551_AT2 and 10632_AT1 and 522_AT1 and 521_AT1 and 516_AT1 and 10476_AT1 and 515_AT1 and 4905_AT1) or (515_AT2 and 522_AT4 and 521_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 518_AT2 and 10476_AT2) or (4905_AT1 and 522_AT5 and 9551_AT3 and 10476_AT2 and 515_AT1 and 521_AT1 and 518_AT1 and 10632_AT1) or (4905_AT1 and 522_AT2 and 10476_AT2 and 518_AT3 and 515_AT2 and 521_AT1 and 9551_AT1 and 10632_AT1) or (522_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 10476_AT2 and 518_AT3 and 515_AT1) or (4905_AT1 and 522_AT5 and 518_AT2 and 10476_AT1 and 515_AT1 and 521_AT1 and 9551_AT1 and 10632_AT1) or (518_AT1 and 522_AT1 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT1) or (4905_AT1 and 515_AT1 and 10476_AT1 and 516_AT1 and 521_AT1 and 522_AT4 and 10632_AT1 and 9551_AT1) or (9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1 and 518_AT2 and 515_AT3 and 10476_AT1 and 4905_AT1) or (4905_AT1 and 515_AT1 and 10476_AT1 and 521_AT1 and 517_AT2 and 9551_AT1 and 522_AT3 and 10632_AT1) or (10476_AT2 and 516_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT1 and 521_AT1 and 515_AT2) or (10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 517_AT2) or (4905_AT1 and 516_AT2 and 9551_AT3 and 515_AT3 and 10476_AT2 and 521_AT1 and 522_AT4 and 10632_AT1) or (4905_AT1 and 522_AT5 and 516_AT1 and 515_AT1 and 10476_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (10476_AT2 and 516_AT1 and 515_AT3 and 9551_AT3 and 522_AT2 and 4905_AT1 and 10632_AT1 and 521_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT4 and 518_AT1 and 10476_AT2 and 515_AT1 and 4905_AT1) or (521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT5 and 516_AT2 and 10476_AT1 and 515_AT1) or (521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT2 and 518_AT3) or (4905_AT1 and 522_AT2 and 9551_AT3 and 516_AT1 and 10476_AT1 and 515_AT2 and 521_AT1 and 10632_AT1) or (515_AT3 and 516_AT1 and 10476_AT1 and 4905_AT1 and 522_AT2 and 10632_AT1 and 9551_AT2 and 521_AT1) or (516_AT1 and 10476_AT1 and 9551_AT3 and 522_AT5 and 4905_AT1 and 10632_AT1 and 515_AT2 and 521_AT1) or (10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 518_AT1 and 515_AT2 and 522_AT4 and 521_AT1) or (9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT1 and 518_AT3 and 521_AT1 and 515_AT2 and 10632_AT1) or (9551_AT2 and 10632_AT1 and 521_AT1 and 515_AT3 and 518_AT3 and 10476_AT2 and 522_AT5 and 4905_AT1) or (4905_AT1 and 515_AT3 and 10476_AT1 and 521_AT1 and 518_AT1 and 522_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 10476_AT1 and 517_AT2 and 515_AT2 and 521_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 10476_AT1 and 515_AT3 and 518_AT2 and 521_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1) or (517_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 522_AT5 and 4905_AT1 and 10476_AT1 and 515_AT3) or (522_AT5 and 4905_AT1 and 10476_AT2 and 518_AT2 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT1) or (10632_AT1 and 9551_AT1 and 517_AT1 and 521_AT1 and 515_AT1 and 10476_AT2 and 4905_AT1 and 522_AT5) or (521_AT1 and 10632_AT1 and 9551_AT1 and 522_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2 and 518_AT2) or (10476_AT1 and 515_AT1 and 4905_AT1 and 516_AT2 and 522_AT2 and 9551_AT2 and 10632_AT1 and 521_AT1) or (4905_AT1 and 10476_AT2 and 515_AT3 and 517_AT1 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (516_AT2 and 522_AT5 and 4905_AT1 and 10476_AT2 and 515_AT3 and 521_AT1 and 10632_AT1 and 9551_AT1) or (518_AT3 and 10476_AT2 and 515_AT3 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT1 and 521_AT1) or (515_AT3 and 10476_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 522_AT4 and 521_AT1 and 518_AT1) or (10476_AT1 and 518_AT3 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT1 and 515_AT2 and 521_AT1) or (4905_AT1 and 522_AT2 and 10476_AT2 and 521_AT1 and 515_AT2 and 517_AT1 and 9551_AT1 and 10632_AT1) or (10632_AT1 and 521_AT1 and 516_AT1 and 10476_AT1 and 515_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3) or (10632_AT1 and 521_AT1 and 517_AT2 and 515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3 and 522_AT2) or (521_AT1 and 522_AT4 and 517_AT2 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT2 and 515_AT1) or (10476_AT1 and 516_AT1 and 4905_AT1 and 522_AT2 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2) or (10632_AT1 and 9551_AT1 and 521_AT1 and 515_AT2 and 10476_AT2 and 518_AT2 and 522_AT2 and 4905_AT1) or (521_AT1 and 10632_AT1 and 9551_AT1 and 522_AT2 and 4905_AT1 and 516_AT2 and 10476_AT2 and 515_AT3) or (516_AT1 and 10476_AT2 and 515_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 521_AT1 and 522_AT1) or (10632_AT1 and 521_AT1 and 517_AT1 and 522_AT1 and 10476_AT1 and 515_AT1 and 4905_AT1 and 9551_AT3) or (10476_AT1 and 522_AT2 and 4905_AT1 and 516_AT2 and 10632_AT1 and 9551_AT1 and 521_AT1 and 515_AT2) or (10632_AT1 and 521_AT1 and 522_AT1 and 517_AT2 and 515_AT3 and 10476_AT1 and 4905_AT1 and 9551_AT3) or (516_AT2 and 4905_AT1 and 10476_AT1 and 515_AT1 and 521_AT1 and 522_AT1 and 9551_AT2 and 10632_AT1) or (10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT2 and 10632_AT1 and 517_AT1 and 515_AT2 and 521_AT1) or (10476_AT1 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 522_AT4 and 517_AT1) or (521_AT1 and 522_AT3 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 518_AT3 and 10476_AT1 and 515_AT1) or (521_AT1 and 515_AT2 and 522_AT1 and 517_AT2 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 10476_AT1) or (4905_AT1 and 10476_AT2 and 516_AT1 and 515_AT3 and 522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1) or (10476_AT1 and 518_AT2 and 522_AT2 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 515_AT2 and 521_AT1) or (10476_AT2 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 515_AT2 and 522_AT4 and 521_AT1 and 518_AT1) or (4905_AT1 and 9551_AT3 and 515_AT1 and 10476_AT1 and 521_AT1 and 522_AT4 and 518_AT1 and 10632_AT1) or (10476_AT2 and 515_AT3 and 4905_AT1 and 516_AT2 and 10632_AT1 and 9551_AT2 and 521_AT1 and 522_AT4) or (4905_AT1 and 516_AT1 and 515_AT1 and 10476_AT1 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1) or (522_AT1 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 10476_AT2 and 515_AT3 and 518_AT2) or (10632_AT1 and 9551_AT2 and 521_AT1 and 518_AT2 and 515_AT3 and 10476_AT2 and 4905_AT1 and 522_AT2) or (4905_AT1 and 522_AT2 and 515_AT3 and 10476_AT1 and 521_AT1 and 517_AT2 and 9551_AT2 and 10632_AT1) or (515_AT3 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT4 and 521_AT1 and 517_AT2) or (10476_AT2 and 518_AT3 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT2 and 522_AT1) or (522_AT5 and 4905_AT1 and 9551_AT3 and 518_AT2 and 515_AT3 and 10476_AT1 and 521_AT1 and 10632_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT1 and 515_AT1 and 10476_AT1 and 518_AT3 and 4905_AT1) or (521_AT1 and 515_AT2 and 522_AT1 and 517_AT2 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 10476_AT1) or (9551_AT2 and 10632_AT1 and 517_AT2 and 521_AT1 and 10476_AT2 and 515_AT3 and 522_AT2 and 4905_AT1) or (515_AT3 and 518_AT2 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT3 and 10632_AT1 and 521_AT1) or (515_AT3 and 10476_AT2 and 516_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 522_AT1) or (521_AT1 and 515_AT2 and 517_AT2 and 10632_AT1 and 522_AT5 and 4905_AT1 and 9551_AT3 and 10476_AT2) or (522_AT3 and 10632_AT1 and 9551_AT1 and 521_AT1 and 515_AT1 and 10476_AT2 and 516_AT1 and 4905_AT1) or (521_AT1 and 10632_AT1 and 4905_AT1 and 516_AT2 and 9551_AT3 and 522_AT2 and 10476_AT1 and 515_AT1) or (522_AT5 and 4905_AT1 and 10476_AT1 and 515_AT1 and 521_AT1 and 517_AT2 and 9551_AT1 and 10632_AT1) or (521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT5 and 4905_AT1 and 516_AT1 and 10476_AT2 and 515_AT3) or (517_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1 and 522_AT2 and 4905_AT1 and 10476_AT1 and 515_AT1) or (515_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 517_AT1 and 522_AT1) or (10632_AT1 and 9551_AT1 and 521_AT1 and 515_AT2 and 10476_AT1 and 518_AT2 and 522_AT5 and 4905_AT1) or (521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 522_AT5 and 516_AT1 and 515_AT1 and 10476_AT1) or (9551_AT1 and 10632_AT1 and 521_AT1 and 515_AT3 and 10476_AT2 and 516_AT1 and 522_AT5 and 4905_AT1) or (516_AT1 and 10476_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 515_AT2 and 522_AT4 and 521_AT1) or (515_AT3 and 10476_AT1 and 516_AT1 and 522_AT5 and 4905_AT1 and 9551_AT1 and 10632_AT1 and 521_AT1) or (521_AT1 and 522_AT4 and 515_AT2 and 10632_AT1 and 9551_AT2 and 4905_AT1 and 516_AT2 and 10476_AT1) or (4905_AT1 and 522_AT5 and 515_AT3 and 10476_AT1 and 521_AT1 and 517_AT2 and 9551_AT2 and 10632_AT1) or (515_AT2 and 522_AT4 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 518_AT3 and 10476_AT1) or (517_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 522_AT5 and 515_AT1 and 10476_AT2) or (515_AT3 and 516_AT1 and 10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT4 and 521_AT1) or (521_AT1 and 10632_AT1 and 9551_AT1 and 522_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2 and 516_AT1) or (515_AT2 and 521_AT1 and 10632_AT1 and 4905_AT1 and 9551_AT3 and 522_AT2 and 518_AT2 and 10476_AT2) or (521_AT1 and 10632_AT1 and 522_AT2 and 9551_AT3 and 4905_AT1 and 10476_AT1 and 518_AT3 and 515_AT1) or (515_AT3 and 518_AT2 and 10476_AT2 and 4905_AT1 and 522_AT3 and 9551_AT2 and 10632_AT1 and 521_AT1) or (10476_AT2 and 515_AT3 and 522_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 517_AT2 and 521_AT1) or (515_AT3 and 518_AT3 and 10476_AT1 and 4905_AT1 and 522_AT2 and 9551_AT3 and 10632_AT1 and 521_AT1) or (521_AT1 and 515_AT2 and 522_AT1 and 517_AT2 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 10476_AT2) or (9551_AT3 and 4905_AT1 and 516_AT1 and 10476_AT1 and 515_AT1 and 521_AT1 and 522_AT3 and 10632_AT1) or (10632_AT1 and 9551_AT1 and 517_AT2 and 522_AT4 and 521_AT1 and 10476_AT2 and 515_AT1 and 4905_AT1) or (4905_AT1 and 10476_AT1 and 518_AT2 and 515_AT2 and 521_AT1 and 522_AT3 and 10632_AT1 and 9551_AT1) or (4905_AT1 and 9551_AT3 and 515_AT1 and 10476_AT1 and 521_AT1 and 517_AT1 and 522_AT3 and 10632_AT1) or (4905_AT1 and 10476_AT2 and 516_AT1 and 515_AT3 and 522_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 10476_AT2 and 515_AT2 and 521_AT1 and 518_AT1 and 9551_AT1 and 522_AT3 and 10632_AT1) or (10632_AT1 and 9551_AT1 and 522_AT1 and 521_AT1 and 515_AT1 and 10476_AT1 and 516_AT2 and 4905_AT1) or (522_AT3 and 9551_AT2 and 10632_AT1 and 517_AT1 and 515_AT2 and 521_AT1 and 10476_AT2 and 4905_AT1) or (10476_AT2 and 515_AT3 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT1 and 518_AT1 and 521_AT1) or (516_AT1 and 10476_AT2 and 515_AT3 and 9551_AT3 and 4905_AT1 and 10632_AT1 and 522_AT1 and 521_AT1) or (4905_AT1 and 522_AT5 and 515_AT3 and 518_AT3 and 10476_AT1 and 521_AT1 and 9551_AT1 and 10632_AT1) or (515_AT1 and 10476_AT1 and 522_AT5 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 517_AT2) or (515_AT1 and 10476_AT1 and 518_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT4 and 521_AT1) or (9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 515_AT1 and 10476_AT2 and 518_AT3 and 4905_AT1) or (515_AT1 and 10476_AT1 and 516_AT2 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 522_AT3 and 521_AT1) or (10476_AT2 and 515_AT1 and 516_AT1 and 4905_AT1 and 10632_AT1 and 9551_AT2 and 521_AT1 and 522_AT4) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT4 and 518_AT2 and 10476_AT2 and 515_AT1 and 4905_AT1) or (515_AT1 and 10476_AT1 and 4905_AT1 and 522_AT5 and 9551_AT3 and 10632_AT1 and 521_AT1 and 518_AT1) or (10476_AT1 and 516_AT1 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 521_AT1 and 515_AT2 and 522_AT1) or (4905_AT1 and 522_AT2 and 515_AT1 and 10476_AT2 and 521_AT1 and 518_AT1 and 9551_AT2 and 10632_AT1) or (10476_AT2 and 515_AT1 and 4905_AT1 and 10632_AT1 and 522_AT3 and 9551_AT1 and 518_AT1 and 521_AT1) or (9551_AT2 and 522_AT3 and 10632_AT1 and 517_AT1 and 521_AT1 and 10476_AT1 and 515_AT3 and 4905_AT1) or (515_AT2 and 521_AT1 and 518_AT1 and 522_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 10476_AT2) or (521_AT1 and 522_AT1 and 518_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 515_AT1 and 10476_AT2) or (4905_AT1 and 10476_AT1 and 522_AT1 and 517_AT2 and 521_AT1 and 515_AT2 and 10632_AT1 and 9551_AT2) or (10476_AT2 and 515_AT1 and 9551_AT3 and 4905_AT1 and 516_AT2 and 10632_AT1 and 521_AT1 and 522_AT4) or (9551_AT2 and 10632_AT1 and 522_AT1 and 515_AT2 and 521_AT1 and 10476_AT2 and 516_AT2 and 4905_AT1) or (10476_AT1 and 522_AT5 and 4905_AT1 and 516_AT2 and 10632_AT1 and 9551_AT2 and 521_AT1 and 515_AT2) or (9551_AT3 and 522_AT5 and 4905_AT1 and 516_AT2 and 10476_AT1 and 515_AT3 and 521_AT1 and 10632_AT1) or (516_AT1 and 515_AT1 and 10476_AT2 and 4905_AT1 and 10632_AT1 and 9551_AT1 and 522_AT4 and 521_AT1) or (522_AT4 and 521_AT1 and 9551_AT1 and 10632_AT1 and 4905_AT1 and 518_AT2 and 515_AT3 and 10476_AT2) or (522_AT3 and 10632_AT1 and 9551_AT1 and 521_AT1 and 10476_AT1 and 515_AT1 and 516_AT1 and 4905_AT1) or (4905_AT1 and 10476_AT2 and 518_AT2 and 522_AT1 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (4905_AT1 and 522_AT5 and 10476_AT2 and 515_AT1 and 518_AT1 and 521_AT1 and 10632_AT1 and 9551_AT2) or (9551_AT2 and 10632_AT1 and 521_AT1 and 518_AT2 and 10476_AT1 and 515_AT1 and 522_AT5 and 4905_AT1) or (518_AT3 and 10476_AT2 and 9551_AT3 and 522_AT5 and 4905_AT1 and 10632_AT1 and 515_AT2 and 521_AT1) or (4905_AT1 and 10476_AT1 and 515_AT1 and 518_AT1 and 522_AT1 and 521_AT1 and 9551_AT2 and 10632_AT1) or (522_AT4 and 515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 518_AT3 and 10476_AT2) or (516_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT2 and 522_AT3 and 10632_AT1 and 515_AT2 and 521_AT1) or (515_AT3 and 10476_AT1 and 518_AT3 and 522_AT5 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 521_AT1) or (4905_AT1 and 522_AT2 and 9551_AT3 and 515_AT1 and 10476_AT1 and 521_AT1 and 518_AT1 and 10632_AT1) or (521_AT1 and 10632_AT1 and 9551_AT3 and 4905_AT1 and 522_AT5 and 10476_AT1 and 516_AT1 and 515_AT3) or (10476_AT1 and 4905_AT1 and 9551_AT2 and 10632_AT1 and 517_AT2 and 515_AT2 and 522_AT4 and 521_AT1) or (515_AT3 and 516_AT1 and 10476_AT2 and 4905_AT1 and 9551_AT3 and 10632_AT1 and 522_AT3 and 521_AT1) or (9551_AT2 and 522_AT3 and 10632_AT1 and 521_AT1 and 517_AT1 and 10476_AT2 and 515_AT1 and 4905_AT1) or (517_AT1 and 521_AT1 and 10632_AT1 and 9551_AT1 and 522_AT2 and 4905_AT1 and 515_AT1 and 10476_AT2) or (10632_AT1 and 521_AT1 and 10476_AT1 and 518_AT3 and 515_AT1 and 522_AT5 and 4905_AT1 and 9551_AT3) or (4905_AT1 and 522_AT5 and 515_AT1 and 10476_AT2 and 518_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1) or (522_AT4 and 515_AT2 and 521_AT1 and 9551_AT2 and 10632_AT1 and 4905_AT1 and 10476_AT2 and 518_AT2) or (9551_AT1 and 10632_AT1 and 521_AT1 and 522_AT4 and 515_AT2 and 518_AT2 and 10476_AT1 and 4905_AT1) or (515_AT2 and 521_AT1 and 10632_AT1 and 9551_AT2 and 516_AT2 and 4905_AT1 and 522_AT2 and 10476_AT1) or (10476_AT2 and 518_AT3 and 515_AT1 and 4905_AT1 and 522_AT5 and 9551_AT2 and 10632_AT1 and 521_AT1) or (9551_AT2 and 10632_AT1 and 517_AT2 and 521_AT1 and 522_AT4 and 10476_AT2 and 515_AT3 and 4905_AT1) or (521_AT1 and 518_AT1 and 9551_AT1 and 10632_AT1 and 522_AT5 and 4905_AT1 and 515_AT3 and 10476_AT1)) and ((509_AT1 and 498_AT3 and 514_AT2 and 513_AT1 and 506_AT1) or (509_AT1 and 498_AT2 and 506_AT1 and 514_AT1 and 513_AT2) or (506_AT1 and 513_AT2 and 509_AT2 and 514_AT2 and 498_AT2) or (509_AT1 and 506_AT1 and 498_AT1 and 513_AT2 and 514_AT1) or (514_AT1 and 513_AT2 and 506_AT1 and 509_AT2 and 498_AT2) or (513_AT1 and 509_AT2 and 514_AT2 and 498_AT2 and 506_AT1) or (509_AT1 and 498_AT3 and 506_AT1 and 513_AT2 and 514_AT1) or (506_AT1 and 513_AT2 and 498_AT3 and 514_AT2 and 509_AT2) or (506_AT1 and 498_AT1 and 513_AT2 and 514_AT1 and 509_AT2) or (514_AT1 and 513_AT2 and 506_AT1 and 509_AT2 and 498_AT3) or (498_AT1 and 506_AT1 and 513_AT2 and 509_AT2 and 514_AT2) or (513_AT2 and 506_AT1 and 514_AT2 and 498_AT3 and 509_AT1) or (509_AT1 and 513_AT1 and 498_AT1 and 506_AT1 and 514_AT1) or (513_AT1 and 514_AT2 and 509_AT1 and 498_AT1 and 506_AT1) or (506_AT1 and 514_AT1 and 509_AT1 and 513_AT1 and 498_AT2) or (498_AT3 and 509_AT2 and 514_AT2 and 513_AT1 and 506_AT1) or (514_AT1 and 506_AT1 and 498_AT1 and 513_AT1 and 509_AT2) or (509_AT1 and 514_AT2 and 498_AT2 and 513_AT1 and 506_AT1) or (509_AT2 and 498_AT2 and 513_AT1 and 506_AT1 and 514_AT1) or (509_AT1 and 498_AT2 and 514_AT2 and 506_AT1 and 513_AT2) or (514_AT1 and 506_AT1 and 509_AT2 and 513_AT1 and 498_AT3) or (513_AT1 and 498_AT3 and 509_AT1 and 514_AT1 and 506_AT1) or (498_AT1 and 506_AT1 and 509_AT2 and 514_AT2 and 513_AT1) or (513_AT2 and 498_AT1 and 506_AT1 and 514_AT2 and 509_AT1))", +"subsystem":"Oxidative Phosphorylation", +"notes":{ +"original_bigg_ids":[ +"ATPS4m" +] +} +}, +{ +"id":"ATPasel", +"name":"V-type ATPase, H+ transporting, lysosomal", +"metabolites":{ +"adp_c":1.0, +"atp_c":-1.0, +"h2o_c":-1.0, +"h_c":-3.0, +"h_l":4.0, +"pi_c":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"((527_AT1 and 533_AT1 and 9114_AT1 and 535_AT1 and 8992_AT1) or (9114_AT1 and 533_AT1 and 8992_AT1 and 23545_AT1 and 527_AT1) or (527_AT1 and 533_AT1 and 9114_AT1 and 10312_AT2 and 8992_AT1) or (10312_AT2 and 8992_AT1 and 533_AT1 and 245972_AT1 and 527_AT1) or (245972_AT1 and 527_AT1 and 8992_AT1 and 23545_AT1 and 533_AT1) or (50617_AT3 and 527_AT1 and 245972_AT1 and 533_AT1 and 8992_AT1) or (8992_AT1 and 9114_AT1 and 533_AT1 and 50617_AT1 and 527_AT1) or (50617_AT3 and 527_AT1 and 8992_AT1 and 9114_AT1 and 533_AT1) or (50617_AT2 and 8992_AT1 and 9114_AT1 and 533_AT1 and 527_AT1) or (533_AT1 and 8992_AT1 and 245972_AT1 and 527_AT1 and 50617_AT1) or (527_AT1 and 245972_AT1 and 533_AT1 and 50617_AT2 and 8992_AT1) or (533_AT1 and 535_AT1 and 8992_AT1 and 527_AT1 and 245972_AT1) or (527_AT1 and 10312_AT1 and 8992_AT1 and 533_AT1 and 9114_AT1) or (533_AT1 and 8992_AT1 and 527_AT1 and 10312_AT1 and 245972_AT1)) and ((51606_AT2 and 90423_AT1 and 523_AT1 and 9296_AT1 and 526_AT1 and 127124_AT2 and 528_AT2 and 51382_AT1) or (51606_AT1 and 523_AT1 and 526_AT1 and 9296_AT1 and 529_AT1 and 534_AT2 and 528_AT2 and 51382_AT1) or (528_AT2 and 529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1 and 51606_AT3 and 523_AT1 and 9550_AT1) or (528_AT2 and 9296_AT1 and 526_AT1 and 51382_AT1 and 127124_AT1 and 523_AT1 and 90423_AT1 and 51606_AT1) or (9550_AT1 and 245973_AT1 and 51606_AT3 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 529_AT1) or (9550_AT1 and 51606_AT1 and 523_AT1 and 525_AT1 and 51382_AT1 and 528_AT1 and 9296_AT1 and 529_AT1) or (51606_AT3 and 523_AT1 and 529_AT1 and 534_AT2 and 526_AT1 and 9296_AT1 and 528_AT1 and 51382_AT1) or (528_AT1 and 51382_AT1 and 529_AT1 and 526_AT1 and 9296_AT1 and 9550_AT1 and 523_AT1 and 51606_AT3) or (523_AT1 and 51606_AT2 and 529_AT1 and 534_AT2 and 9296_AT1 and 526_AT1 and 528_AT1 and 51382_AT1) or (523_AT1 and 51606_AT3 and 127124_AT1 and 90423_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1 and 525_AT1) or (51382_AT1 and 534_AT2 and 529_AT1 and 526_AT1 and 9296_AT1 and 523_AT1 and 245973_AT1 and 51606_AT2) or (9296_AT1 and 529_AT1 and 534_AT2 and 525_AT1 and 51382_AT1 and 528_AT1 and 51606_AT2 and 523_AT1) or (90423_AT1 and 51606_AT1 and 245973_AT1 and 523_AT1 and 51382_AT1 and 526_AT1 and 9296_AT1 and 534_AT2) or (127124_AT1 and 523_AT1 and 51606_AT3 and 51382_AT1 and 9296_AT1 and 526_AT1 and 528_AT2 and 529_AT1) or (523_AT1 and 51606_AT1 and 245973_AT1 and 90423_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1) or (9550_AT1 and 523_AT1 and 51606_AT1 and 245973_AT1 and 51382_AT1 and 525_AT1 and 529_AT1 and 9296_AT1) or (525_AT1 and 51382_AT1 and 528_AT1 and 9296_AT1 and 534_AT2 and 51606_AT1 and 90423_AT1 and 523_AT1) or (51382_AT1 and 529_AT1 and 528_AT2 and 526_AT1 and 127124_AT2 and 9296_AT1 and 51606_AT3 and 523_AT1) or (90423_AT1 and 127124_AT1 and 523_AT1 and 51606_AT3 and 9296_AT1 and 526_AT1 and 51382_AT1 and 528_AT1) or (51382_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1 and 528_AT2 and 90423_AT1 and 523_AT1 and 51606_AT3) or (90423_AT1 and 51606_AT1 and 523_AT1 and 526_AT1 and 9296_AT1 and 534_AT2 and 528_AT2 and 51382_AT1) or (245973_AT1 and 127124_AT1 and 523_AT1 and 51606_AT3 and 51382_AT1 and 9296_AT1 and 526_AT1 and 529_AT1) or (526_AT1 and 9296_AT1 and 51382_AT1 and 90423_AT1 and 245973_AT1 and 523_AT1 and 51606_AT3 and 127124_AT1) or (9296_AT1 and 534_AT2 and 525_AT1 and 51382_AT1 and 90423_AT1 and 245973_AT1 and 51606_AT3 and 523_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2 and 51606_AT1 and 534_AT1 and 90423_AT1 and 523_AT1) or (525_AT1 and 528_AT1 and 51382_AT1 and 127124_AT2 and 9296_AT1 and 529_AT1 and 523_AT1 and 51606_AT3) or (51382_AT1 and 526_AT1 and 9296_AT1 and 529_AT1 and 534_AT1 and 245973_AT1 and 51606_AT2 and 523_AT1) or (529_AT1 and 528_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1 and 523_AT1 and 51606_AT1 and 9550_AT1) or (523_AT1 and 51606_AT1 and 90423_AT1 and 9550_AT1 and 9296_AT1 and 528_AT1 and 51382_AT1 and 525_AT1) or (523_AT1 and 245973_AT1 and 51606_AT1 and 51382_AT1 and 529_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1) or (90423_AT1 and 51606_AT1 and 523_AT1 and 9296_AT1 and 526_AT1 and 127124_AT2 and 528_AT2 and 51382_AT1) or (51382_AT1 and 528_AT1 and 526_AT1 and 9296_AT1 and 529_AT1 and 534_AT1 and 523_AT1 and 51606_AT3) or (523_AT1 and 51606_AT2 and 90423_AT1 and 534_AT2 and 9296_AT1 and 528_AT1 and 51382_AT1 and 525_AT1) or (245973_AT1 and 51606_AT2 and 523_AT1 and 9296_AT1 and 529_AT1 and 534_AT2 and 525_AT1 and 51382_AT1) or (523_AT1 and 51606_AT2 and 90423_AT1 and 528_AT2 and 9296_AT1 and 127124_AT2 and 51382_AT1 and 525_AT1) or (523_AT1 and 51606_AT1 and 245973_AT1 and 534_AT1 and 529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1) or (523_AT1 and 51606_AT2 and 534_AT1 and 90423_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1 and 525_AT1) or (528_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1 and 51606_AT3 and 523_AT1 and 534_AT1 and 90423_AT1) or (523_AT1 and 51606_AT3 and 245973_AT1 and 534_AT1 and 529_AT1 and 9296_AT1 and 526_AT1 and 51382_AT1) or (245973_AT1 and 51606_AT1 and 90423_AT1 and 523_AT1 and 127124_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1) or (523_AT1 and 90423_AT1 and 51606_AT1 and 9296_AT1 and 127124_AT2 and 528_AT1 and 51382_AT1 and 525_AT1) or (523_AT1 and 127124_AT1 and 245973_AT1 and 90423_AT1 and 51606_AT2 and 51382_AT1 and 525_AT1 and 9296_AT1) or (534_AT2 and 9296_AT1 and 526_AT1 and 51382_AT1 and 523_AT1 and 51606_AT2 and 245973_AT1 and 90423_AT1) or (51382_AT1 and 528_AT1 and 526_AT1 and 9296_AT1 and 534_AT1 and 90423_AT1 and 51606_AT3 and 523_AT1) or (528_AT2 and 9296_AT1 and 526_AT1 and 51382_AT1 and 523_AT1 and 534_AT1 and 51606_AT1 and 90423_AT1) or (523_AT1 and 245973_AT1 and 90423_AT1 and 51606_AT2 and 51382_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1) or (90423_AT1 and 51606_AT3 and 523_AT1 and 9550_AT1 and 526_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1) or (529_AT1 and 9296_AT1 and 526_AT1 and 127124_AT2 and 51382_AT1 and 523_AT1 and 51606_AT3 and 245973_AT1) or (529_AT1 and 528_AT2 and 9296_AT1 and 51382_AT1 and 525_AT1 and 51606_AT3 and 523_AT1 and 534_AT1) or (127124_AT1 and 523_AT1 and 51606_AT1 and 529_AT1 and 9296_AT1 and 528_AT1 and 51382_AT1 and 525_AT1) or (523_AT1 and 51606_AT3 and 9550_AT1 and 528_AT2 and 529_AT1 and 9296_AT1 and 526_AT1 and 51382_AT1) or (51382_AT1 and 528_AT1 and 526_AT1 and 9296_AT1 and 534_AT2 and 90423_AT1 and 51606_AT3 and 523_AT1) or (529_AT1 and 528_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1 and 523_AT1 and 534_AT1 and 51606_AT2) or (529_AT1 and 9296_AT1 and 526_AT1 and 528_AT1 and 51382_AT1 and 523_AT1 and 51606_AT2 and 9550_AT1) or (9296_AT1 and 526_AT1 and 127124_AT2 and 529_AT1 and 51382_AT1 and 528_AT1 and 51606_AT2 and 523_AT1) or (523_AT1 and 51606_AT1 and 51382_AT1 and 528_AT1 and 529_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1) or (523_AT1 and 51606_AT3 and 525_AT1 and 51382_AT1 and 9296_AT1 and 534_AT2 and 529_AT1 and 528_AT2) or (523_AT1 and 245973_AT1 and 51606_AT2 and 51382_AT1 and 529_AT1 and 526_AT1 and 127124_AT2 and 9296_AT1) or (9296_AT1 and 528_AT2 and 525_AT1 and 51382_AT1 and 51606_AT1 and 90423_AT1 and 523_AT1 and 9550_AT1) or (528_AT2 and 534_AT2 and 9296_AT1 and 526_AT1 and 51382_AT1 and 51606_AT3 and 523_AT1 and 90423_AT1) or (51382_AT1 and 528_AT2 and 526_AT1 and 9296_AT1 and 9550_AT1 and 523_AT1 and 51606_AT3 and 90423_AT1) or (90423_AT1 and 127124_AT1 and 51606_AT3 and 523_AT1 and 9296_AT1 and 528_AT2 and 525_AT1 and 51382_AT1) or (534_AT1 and 90423_AT1 and 245973_AT1 and 51606_AT1 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1) or (9296_AT1 and 534_AT2 and 529_AT1 and 528_AT2 and 525_AT1 and 51382_AT1 and 51606_AT2 and 523_AT1) or (127124_AT1 and 523_AT1 and 51606_AT3 and 529_AT1 and 9296_AT1 and 528_AT1 and 51382_AT1 and 525_AT1) or (528_AT1 and 51382_AT1 and 526_AT1 and 9296_AT1 and 90423_AT1 and 534_AT1 and 51606_AT2 and 523_AT1) or (51382_AT1 and 528_AT1 and 9296_AT1 and 526_AT1 and 51606_AT2 and 90423_AT1 and 127124_AT1 and 523_AT1) or (9296_AT1 and 526_AT1 and 528_AT2 and 529_AT1 and 51382_AT1 and 534_AT1 and 51606_AT1 and 523_AT1) or (9296_AT1 and 528_AT1 and 51382_AT1 and 525_AT1 and 523_AT1 and 127124_AT1 and 51606_AT1 and 90423_AT1) or (51606_AT1 and 245973_AT1 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 127124_AT2 and 529_AT1) or (526_AT1 and 9296_AT1 and 529_AT1 and 51382_AT1 and 245973_AT1 and 51606_AT3 and 523_AT1 and 9550_AT1) or (51382_AT1 and 9296_AT1 and 526_AT1 and 529_AT1 and 9550_AT1 and 51606_AT2 and 245973_AT1 and 523_AT1) or (51382_AT1 and 525_AT1 and 528_AT2 and 529_AT1 and 9296_AT1 and 127124_AT1 and 51606_AT3 and 523_AT1) or (51382_AT1 and 528_AT1 and 525_AT1 and 127124_AT2 and 9296_AT1 and 523_AT1 and 51606_AT3 and 90423_AT1) or (523_AT1 and 245973_AT1 and 51606_AT1 and 9550_AT1 and 529_AT1 and 9296_AT1 and 526_AT1 and 51382_AT1) or (9296_AT1 and 525_AT1 and 528_AT1 and 51382_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 9550_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2 and 534_AT2 and 90423_AT1 and 523_AT1 and 51606_AT3) or (51382_AT1 and 526_AT1 and 9296_AT1 and 528_AT2 and 90423_AT1 and 51606_AT3 and 523_AT1 and 127124_AT1) or (523_AT1 and 127124_AT1 and 51606_AT2 and 51382_AT1 and 529_AT1 and 528_AT2 and 526_AT1 and 9296_AT1) or (523_AT1 and 51606_AT1 and 245973_AT1 and 534_AT2 and 529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1) or (51382_AT1 and 525_AT1 and 9296_AT1 and 127124_AT2 and 523_AT1 and 51606_AT1 and 245973_AT1 and 90423_AT1) or (9550_AT1 and 51606_AT1 and 523_AT1 and 51382_AT1 and 528_AT1 and 9296_AT1 and 526_AT1 and 529_AT1) or (9550_AT1 and 51606_AT2 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 529_AT1 and 528_AT2) or (51382_AT1 and 528_AT2 and 9296_AT1 and 526_AT1 and 127124_AT1 and 523_AT1 and 51606_AT2 and 90423_AT1) or (127124_AT2 and 9296_AT1 and 529_AT1 and 528_AT2 and 525_AT1 and 51382_AT1 and 51606_AT1 and 523_AT1) or (51606_AT1 and 523_AT1 and 9296_AT1 and 526_AT1 and 534_AT2 and 529_AT1 and 528_AT1 and 51382_AT1) or (529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1 and 127124_AT1 and 523_AT1 and 245973_AT1 and 51606_AT1) or (528_AT1 and 51382_AT1 and 525_AT1 and 9296_AT1 and 523_AT1 and 90423_AT1 and 534_AT1 and 51606_AT1) or (529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1 and 523_AT1 and 51606_AT2 and 534_AT1 and 245973_AT1) or (245973_AT1 and 51606_AT2 and 523_AT1 and 127124_AT1 and 9296_AT1 and 529_AT1 and 525_AT1 and 51382_AT1) or (9296_AT1 and 529_AT1 and 525_AT1 and 528_AT1 and 51382_AT1 and 51606_AT1 and 534_AT1 and 523_AT1) or (90423_AT1 and 523_AT1 and 51606_AT3 and 525_AT1 and 51382_AT1 and 127124_AT2 and 9296_AT1 and 528_AT2) or (9296_AT1 and 529_AT1 and 525_AT1 and 51382_AT1 and 528_AT1 and 51606_AT3 and 523_AT1 and 9550_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2 and 529_AT1 and 51606_AT1 and 127124_AT1 and 523_AT1) or (529_AT1 and 526_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1 and 523_AT1 and 534_AT1 and 51606_AT2) or (523_AT1 and 51606_AT1 and 534_AT1 and 528_AT1 and 51382_AT1 and 529_AT1 and 526_AT1 and 9296_AT1) or (528_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1 and 523_AT1 and 51606_AT1 and 90423_AT1 and 9550_AT1) or (51606_AT1 and 523_AT1 and 51382_AT1 and 9296_AT1 and 127124_AT2 and 526_AT1 and 528_AT2 and 529_AT1) or (51382_AT1 and 529_AT1 and 9296_AT1 and 526_AT1 and 523_AT1 and 534_AT1 and 51606_AT1 and 245973_AT1) or (51606_AT1 and 523_AT1 and 127124_AT1 and 51382_AT1 and 526_AT1 and 9296_AT1 and 529_AT1 and 528_AT2) or (523_AT1 and 51606_AT3 and 245973_AT1 and 90423_AT1 and 9296_AT1 and 526_AT1 and 127124_AT2 and 51382_AT1) or (51606_AT3 and 523_AT1 and 245973_AT1 and 534_AT2 and 529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1) or (9550_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2) or (51606_AT3 and 523_AT1 and 127124_AT1 and 90423_AT1 and 245973_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 534_AT2 and 245973_AT1 and 51606_AT1 and 90423_AT1 and 523_AT1) or (51606_AT2 and 523_AT1 and 127124_AT1 and 525_AT1 and 528_AT1 and 51382_AT1 and 9296_AT1 and 529_AT1) or (51606_AT2 and 245973_AT1 and 523_AT1 and 9296_AT1 and 127124_AT2 and 529_AT1 and 525_AT1 and 51382_AT1) or (51382_AT1 and 9296_AT1 and 526_AT1 and 90423_AT1 and 51606_AT1 and 245973_AT1 and 127124_AT1 and 523_AT1) or (529_AT1 and 9296_AT1 and 127124_AT2 and 528_AT1 and 51382_AT1 and 525_AT1 and 523_AT1 and 51606_AT1) or (51382_AT1 and 529_AT1 and 528_AT2 and 526_AT1 and 9296_AT1 and 523_AT1 and 51606_AT3 and 534_AT1) or (523_AT1 and 90423_AT1 and 51606_AT1 and 534_AT2 and 528_AT2 and 9296_AT1 and 51382_AT1 and 525_AT1) or (127124_AT2 and 9296_AT1 and 528_AT2 and 525_AT1 and 51382_AT1 and 51606_AT1 and 90423_AT1 and 523_AT1) or (523_AT1 and 51606_AT2 and 9550_AT1 and 529_AT1 and 528_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1) or (90423_AT1 and 245973_AT1 and 523_AT1 and 51606_AT3 and 127124_AT2 and 9296_AT1 and 525_AT1 and 51382_AT1) or (523_AT1 and 51606_AT3 and 245973_AT1 and 51382_AT1 and 534_AT2 and 529_AT1 and 9296_AT1 and 526_AT1) or (523_AT1 and 534_AT1 and 90423_AT1 and 245973_AT1 and 51606_AT2 and 51382_AT1 and 526_AT1 and 9296_AT1) or (523_AT1 and 51606_AT2 and 534_AT1 and 529_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1 and 525_AT1) or (523_AT1 and 127124_AT1 and 245973_AT1 and 51606_AT1 and 529_AT1 and 526_AT1 and 9296_AT1 and 51382_AT1) or (534_AT2 and 526_AT1 and 9296_AT1 and 528_AT1 and 51382_AT1 and 523_AT1 and 90423_AT1 and 51606_AT2) or (9550_AT1 and 523_AT1 and 51606_AT1 and 51382_AT1 and 525_AT1 and 529_AT1 and 528_AT2 and 9296_AT1) or (9296_AT1 and 528_AT2 and 529_AT1 and 534_AT2 and 525_AT1 and 51382_AT1 and 51606_AT1 and 523_AT1) or (523_AT1 and 127124_AT1 and 90423_AT1 and 51606_AT1 and 526_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1) or (526_AT1 and 9296_AT1 and 528_AT1 and 51382_AT1 and 90423_AT1 and 51606_AT1 and 523_AT1 and 9550_AT1) or (523_AT1 and 534_AT1 and 51606_AT2 and 529_AT1 and 528_AT2 and 9296_AT1 and 51382_AT1 and 525_AT1) or (9550_AT1 and 523_AT1 and 51606_AT2 and 245973_AT1 and 90423_AT1 and 51382_AT1 and 9296_AT1 and 526_AT1) or (528_AT1 and 51382_AT1 and 525_AT1 and 9296_AT1 and 127124_AT2 and 523_AT1 and 51606_AT2 and 90423_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 529_AT1 and 245973_AT1 and 127124_AT1 and 51606_AT3 and 523_AT1) or (127124_AT1 and 523_AT1 and 51606_AT2 and 90423_AT1 and 528_AT1 and 51382_AT1 and 525_AT1 and 9296_AT1) or (51382_AT1 and 528_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1) or (127124_AT2 and 526_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1 and 523_AT1 and 51606_AT1 and 90423_AT1) or (51382_AT1 and 525_AT1 and 529_AT1 and 528_AT2 and 9296_AT1 and 523_AT1 and 127124_AT1 and 51606_AT2) or (529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1 and 51606_AT3 and 523_AT1 and 245973_AT1 and 534_AT1) or (51606_AT3 and 523_AT1 and 51382_AT1 and 9296_AT1 and 526_AT1 and 528_AT2 and 534_AT2 and 529_AT1) or (9296_AT1 and 526_AT1 and 51382_AT1 and 127124_AT1 and 523_AT1 and 51606_AT2 and 90423_AT1 and 245973_AT1) or (523_AT1 and 51606_AT2 and 90423_AT1 and 9550_AT1 and 9296_AT1 and 526_AT1 and 51382_AT1 and 528_AT1) or (9296_AT1 and 526_AT1 and 528_AT2 and 534_AT2 and 51382_AT1 and 51606_AT2 and 90423_AT1 and 523_AT1) or (9550_AT1 and 523_AT1 and 51606_AT3 and 245973_AT1 and 90423_AT1 and 51382_AT1 and 9296_AT1 and 526_AT1) or (9296_AT1 and 525_AT1 and 51382_AT1 and 245973_AT1 and 90423_AT1 and 51606_AT2 and 523_AT1 and 9550_AT1) or (534_AT2 and 9296_AT1 and 51382_AT1 and 525_AT1 and 523_AT1 and 51606_AT2 and 90423_AT1 and 245973_AT1) or (534_AT2 and 529_AT1 and 526_AT1 and 9296_AT1 and 51382_AT1 and 523_AT1 and 245973_AT1 and 51606_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 9550_AT1 and 90423_AT1 and 245973_AT1 and 523_AT1 and 51606_AT3) or (51606_AT2 and 90423_AT1 and 127124_AT1 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2) or (9550_AT1 and 245973_AT1 and 51606_AT2 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 529_AT1) or (523_AT1 and 245973_AT1 and 90423_AT1 and 534_AT1 and 51606_AT2 and 51382_AT1 and 525_AT1 and 9296_AT1) or (9296_AT1 and 528_AT2 and 525_AT1 and 51382_AT1 and 90423_AT1 and 523_AT1 and 51606_AT3 and 9550_AT1) or (51606_AT2 and 523_AT1 and 526_AT1 and 127124_AT2 and 9296_AT1 and 529_AT1 and 528_AT2 and 51382_AT1) or (526_AT1 and 9296_AT1 and 51382_AT1 and 245973_AT1 and 534_AT1 and 90423_AT1 and 523_AT1 and 51606_AT3) or (51382_AT1 and 525_AT1 and 528_AT2 and 9296_AT1 and 51606_AT3 and 523_AT1 and 90423_AT1 and 534_AT1) or (9296_AT1 and 51382_AT1 and 525_AT1 and 523_AT1 and 245973_AT1 and 51606_AT1 and 90423_AT1 and 9550_AT1) or (523_AT1 and 534_AT1 and 90423_AT1 and 51606_AT2 and 51382_AT1 and 525_AT1 and 528_AT2 and 9296_AT1) or (51382_AT1 and 528_AT1 and 127124_AT2 and 526_AT1 and 9296_AT1 and 90423_AT1 and 523_AT1 and 51606_AT3) or (523_AT1 and 51606_AT2 and 534_AT1 and 90423_AT1 and 528_AT2 and 9296_AT1 and 526_AT1 and 51382_AT1) or (529_AT1 and 9296_AT1 and 526_AT1 and 51382_AT1 and 528_AT1 and 127124_AT1 and 523_AT1 and 51606_AT1) or (51606_AT2 and 127124_AT1 and 523_AT1 and 51382_AT1 and 528_AT1 and 9296_AT1 and 526_AT1 and 529_AT1) or (525_AT1 and 528_AT1 and 51382_AT1 and 9296_AT1 and 127124_AT2 and 529_AT1 and 51606_AT2 and 523_AT1) or (90423_AT1 and 245973_AT1 and 51606_AT3 and 523_AT1 and 51382_AT1 and 526_AT1 and 9296_AT1 and 534_AT2) or (51382_AT1 and 528_AT1 and 9296_AT1 and 526_AT1 and 523_AT1 and 51606_AT1 and 534_AT1 and 90423_AT1) or (51382_AT1 and 528_AT1 and 525_AT1 and 9296_AT1 and 9550_AT1 and 523_AT1 and 51606_AT3 and 90423_AT1) or (523_AT1 and 51606_AT1 and 534_AT1 and 528_AT2 and 529_AT1 and 9296_AT1 and 51382_AT1 and 525_AT1) or (528_AT1 and 51382_AT1 and 526_AT1 and 127124_AT2 and 9296_AT1 and 529_AT1 and 523_AT1 and 51606_AT3) or (90423_AT1 and 51606_AT1 and 523_AT1 and 528_AT1 and 51382_AT1 and 526_AT1 and 9296_AT1 and 534_AT2) or (51382_AT1 and 528_AT2 and 526_AT1 and 9296_AT1 and 9550_AT1 and 523_AT1 and 90423_AT1 and 51606_AT2) or (127124_AT1 and 523_AT1 and 51606_AT2 and 245973_AT1 and 51382_AT1 and 529_AT1 and 9296_AT1 and 526_AT1) or (525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2 and 534_AT2 and 51606_AT2 and 90423_AT1 and 523_AT1) or (51606_AT3 and 523_AT1 and 525_AT1 and 51382_AT1 and 127124_AT2 and 9296_AT1 and 529_AT1 and 528_AT2) or (51382_AT1 and 525_AT1 and 9296_AT1 and 523_AT1 and 51606_AT3 and 90423_AT1 and 245973_AT1 and 534_AT1) or (9296_AT1 and 526_AT1 and 51382_AT1 and 523_AT1 and 534_AT1 and 51606_AT1 and 90423_AT1 and 245973_AT1) or (51606_AT1 and 523_AT1 and 525_AT1 and 528_AT1 and 51382_AT1 and 9296_AT1 and 529_AT1 and 534_AT2) or (127124_AT2 and 9296_AT1 and 51382_AT1 and 525_AT1 and 523_AT1 and 245973_AT1 and 90423_AT1 and 51606_AT2) or (51606_AT3 and 523_AT1 and 534_AT1 and 90423_AT1 and 51382_AT1 and 528_AT1 and 525_AT1 and 9296_AT1) or (51606_AT2 and 523_AT1 and 9550_AT1 and 9296_AT1 and 529_AT1 and 525_AT1 and 51382_AT1 and 528_AT1) or (90423_AT1 and 51606_AT3 and 523_AT1 and 525_AT1 and 51382_AT1 and 528_AT1 and 9296_AT1 and 534_AT2) or (523_AT1 and 51606_AT3 and 245973_AT1 and 51382_AT1 and 525_AT1 and 529_AT1 and 9296_AT1 and 127124_AT2) or (51382_AT1 and 525_AT1 and 528_AT2 and 529_AT1 and 9296_AT1 and 127124_AT2 and 523_AT1 and 51606_AT2) or (90423_AT1 and 51606_AT1 and 127124_AT1 and 523_AT1 and 525_AT1 and 51382_AT1 and 9296_AT1 and 528_AT2) or (526_AT1 and 9296_AT1 and 51382_AT1 and 523_AT1 and 245973_AT1 and 51606_AT1 and 90423_AT1 and 9550_AT1) or (523_AT1 and 51606_AT3 and 534_AT1 and 529_AT1 and 9296_AT1 and 51382_AT1 and 528_AT1 and 525_AT1) or (525_AT1 and 51382_AT1 and 528_AT1 and 9296_AT1 and 534_AT2 and 529_AT1 and 51606_AT3 and 523_AT1) or (51606_AT2 and 523_AT1 and 51382_AT1 and 9296_AT1 and 526_AT1 and 528_AT2 and 529_AT1 and 534_AT2) or (9296_AT1 and 526_AT1 and 529_AT1 and 528_AT1 and 51382_AT1 and 127124_AT1 and 523_AT1 and 51606_AT3))", +"subsystem":"Transport, Lysosomal", +"notes":{ +"original_bigg_ids":[ +"ATPasel" +] +} +}, +{ +"id":"ATPtm", +"name":"ADP/ATP transporter, mitochondrial", +"metabolites":{ +"adp_c":-1.0, +"adp_m":1.0, +"atp_c":1.0, +"atp_m":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"293_AT1 or 292_AT1 or 291_AT1", +"subsystem":"Transport, Mitochondrial", +"notes":{ +"original_bigg_ids":[ +"ATPtm" +] +} +}, +{ +"id":"ATPtn", +"name":"ATP diffusion in nucleus", +"metabolites":{ +"atp_c":-1.0, +"atp_n":1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Nuclear", +"notes":{ +"original_bigg_ids":[ +"ATPtn" +] +} +}, +{ +"id":"ATPtx", +"name":"ATP transporter, peroxisomal", +"metabolites":{ +"atp_c":-1.0, +"atp_x":1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Peroxisomal", +"notes":{ +"original_bigg_ids":[ +"ATPtx" +] +} +}, +{ +"id":"AVITE1t", +"name":"Alpha-Tocopherol (Vit. E) transport", +"metabolites":{ +"avite1_c":1.0, +"avite1_e":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Extracellular", +"notes":{ +"original_bigg_ids":[ +"AVITE1t" +] +} +}, +{ +"id":"AVITE2t", +"name":"Alpha-tocotrienol (Vit. E) transport", +"metabolites":{ +"avite2_c":1.0, +"avite2_e":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Extracellular", +"notes":{ +"original_bigg_ids":[ +"AVITE2t" +] +} +}, +{ +"id":"A_MANASE", +"name":"Alpha-mannosidase", +"metabolites":{ +"h2o_c":-2.0, +"m2mn_c":-1.0, +"man_c":2.0, +"mn_c":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"4123_AT1", +"subsystem":"N-Glycan Degradation", +"notes":{ +"original_bigg_ids":[ +"A_MANASE" +] +} +}, +{ +"id":"A_MANASEly", +"name":"Alpha-mannosidase, lysosomal", +"metabolites":{ +"h2o_l":-2.0, +"m2mn_l":-1.0, +"man_l":2.0, +"mn_l":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"4125_AT1", +"subsystem":"N-Glycan Degradation", +"notes":{ +"original_bigg_ids":[ +"A_MANASEly" +] +} +}, +{ +"id":"B3GALT3g", +"name":"Beta-1,3-galactosyltransferase 3", +"metabolites":{ +"gbside_hs_g":1.0, +"h_g":1.0, +"thcrm_hs_g":-1.0, +"udp_g":1.0, 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(3073_AT1 and 3074_AT1)", +"subsystem":"Chondroitin sulfate degradation", +"notes":{ +"original_bigg_ids":[ +"NACHEXA7ly" +] +} +}, +{ +"id":"NACHEXA8ly", +"name":"Beta-N-acetylhexosaminidase A, lysosomal", +"metabolites":{ +"acgal_l":1.0, +"cs_e_deg4_l":-1.0, +"cs_e_deg7_l":1.0, +"h2o_l":-3.0, +"h_l":2.0, +"so4_l":2.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"3073_AT1 or (3073_AT1 and 3074_AT1)", +"subsystem":"Chondroitin sulfate degradation", +"notes":{ +"original_bigg_ids":[ +"NACHEXA8ly" +] +} +}, +{ +"id":"NACHEXA9ly", +"name":"Beta-N-acetylhexosaminidase A, lysosomal", +"metabolites":{ +"acgam_l":2.0, +"h2o_l":-3.0, +"h_l":1.0, +"ksi_deg6_l":-1.0, +"ksi_deg8_l":1.0, +"so4_l":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"(3073_AT1 and 3074_AT1) or 3073_AT1", +"subsystem":"Keratan sulfate degradation", +"notes":{ +"original_bigg_ids":[ +"NACHEXA9ly" +] +} +}, +{ +"id":"NACt", +"name":"Nicotinic acid transport", +"metabolites":{ +"nac_c":1.0, +"nac_e":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Extracellular", +"notes":{ +"original_bigg_ids":[ +"NACUP" +] +} +}, +{ +"id":"NADH2_u10m", +"name":"NADH dehydrogenase, mitochondrial", +"metabolites":{ +"h_c":4.0, +"h_m":-5.0, +"nad_m":1.0, +"nadh_m":-1.0, +"q10_m":-1.0, +"q10h2_m":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"(4698_AT1 and 4701_AT1 and 4724_AT1 and 4538_AT1 and 4540_AT1 and 4717_AT1 and 126328_AT1 and 4719_AT1 and 4714_AT1 and 4713_AT1 and 4723_AT1 and 4715_AT1 and 4710_AT1 and 4700_AT1 and 4535_AT1 and 4539_AT1 and 4702_AT1 and 4731_AT1 and 4711_AT1 and 4706_AT1 and 4541_AT1 and 7991_AT2 and 4537_AT1 and 4705_AT1 and 4704_AT1 and 51079_AT1 and 374291_AT1 and 4722_AT1 and 4536_AT1 and 4712_AT2 and 4716_AT1 and 4725_AT1 and 4707_AT1 and 4694_AT1 and 4718_AT1 and 4726_AT1 and 4696_AT1 and 4708_AT1 and 4720_AT1 and 4728_AT1 and 4709_AT1 and 4697_AT1 and 4695_AT1 and 55967_AT1 and 4729_AT1) or (4728_AT1 and 4708_AT1 and 4720_AT1 and 55967_AT1 and 4695_AT1 and 4729_AT1 and 4709_AT1 and 4697_AT1 and 51079_AT1 and 7991_AT1 and 374291_AT1 and 4536_AT1 and 4722_AT1 and 4731_AT2 and 4537_AT1 and 4705_AT1 and 4704_AT1 and 4707_AT1 and 4694_AT1 and 4718_AT1 and 4726_AT1 and 4696_AT1 and 4712_AT2 and 4716_AT1 and 4725_AT1 and 4713_AT1 and 4723_AT1 and 4714_AT1 and 4535_AT1 and 4539_AT1 and 4702_AT1 and 4711_AT1 and 4541_AT1 and 4706_AT1 and 4715_AT1 and 4710_AT1 and 4700_AT1 and 4538_AT1 and 4540_AT1 and 126328_AT1 and 4717_AT1 and 4698_AT1 and 4724_AT1 and 4701_AT1 and 4719_AT1) or (4715_AT1 and 4710_AT1 and 4700_AT1 and 4535_AT1 and 4539_AT1 and 4702_AT1 and 4706_AT1 and 4711_AT1 and 4541_AT1 and 4714_AT1 and 4713_AT1 and 4723_AT1 and 4719_AT1 and 4698_AT1 and 4724_AT1 and 4701_AT1 and 4538_AT1 and 4540_AT1 and 4717_AT1 and 126328_AT1 and 4709_AT1 and 4697_AT1 and 4695_AT1 and 55967_AT1 and 4729_AT1 and 4720_AT1 and 4708_AT1 and 4728_AT1 and 4712_AT2 and 4716_AT1 and 4725_AT1 and 4694_AT1 and 4718_AT1 and 4707_AT1 and 4726_AT1 and 4696_AT1 and 7991_AT2 and 4731_AT2 and 4537_AT1 and 4704_AT1 and 4705_AT1 and 51079_AT1 and 374291_AT1 and 4722_AT1 and 4536_AT1) or (4719_AT1 and 4538_AT1 and 126328_AT1 and 4717_AT1 and 4540_AT1 and 4698_AT1 and 4701_AT1 and 4724_AT1 and 4702_AT1 and 4535_AT1 and 4539_AT1 and 4541_AT1 and 4711_AT1 and 4706_AT1 and 4712_AT1 and 4710_AT1 and 4715_AT1 and 4700_AT1 and 4713_AT1 and 4723_AT1 and 4714_AT1 and 4707_AT1 and 4718_AT1 and 4694_AT1 and 4696_AT1 and 4726_AT1 and 4725_AT1 and 4716_AT1 and 374291_AT1 and 51079_AT1 and 4722_AT1 and 4536_AT1 and 7991_AT2 and 4704_AT1 and 4705_AT1 and 4537_AT1 and 4731_AT2 and 4695_AT1 and 55967_AT1 and 4729_AT1 and 4709_AT1 and 4697_AT1 and 4728_AT1 and 4708_AT1 and 4720_AT1) or (4725_AT1 and 4716_AT1 and 4694_AT1 and 4707_AT1 and 4718_AT1 and 4696_AT1 and 4726_AT1 and 7991_AT2 and 4704_AT1 and 4705_AT1 and 4537_AT1 and 374291_AT1 and 51079_AT1 and 4722_AT1 and 4536_AT1 and 4709_AT1 and 4697_AT1 and 55967_AT1 and 4695_AT1 and 4729_AT1 and 4720_AT1 and 4708_AT1 and 4728_AT1 and 4719_AT1 and 4698_AT1 and 4701_AT1 and 4724_AT1 and 4538_AT1 and 4717_AT1 and 126328_AT1 and 4540_AT1 and 4715_AT1 and 4710_AT1 and 4700_AT1 and 4535_AT1 and 4702_AT1 and 4539_AT1 and 4711_AT1 and 4706_AT1 and 4541_AT1 and 4712_AT1 and 4731_AT1 and 4714_AT1 and 4713_AT1 and 4723_AT1) or (4723_AT1 and 4713_AT1 and 4714_AT1 and 4731_AT1 and 4712_AT1 and 4541_AT1 and 4711_AT1 and 4706_AT1 and 4535_AT1 and 4702_AT1 and 4539_AT1 and 4700_AT1 and 4715_AT1 and 4710_AT1 and 4540_AT1 and 4717_AT1 and 126328_AT1 and 4538_AT1 and 4701_AT1 and 4724_AT1 and 4698_AT1 and 4719_AT1 and 4728_AT1 and 4720_AT1 and 4708_AT1 and 4729_AT1 and 4695_AT1 and 55967_AT1 and 4697_AT1 and 4709_AT1 and 4536_AT1 and 4722_AT1 and 51079_AT1 and 7991_AT1 and 374291_AT1 and 4537_AT1 and 4704_AT1 and 4705_AT1 and 4726_AT1 and 4696_AT1 and 4694_AT1 and 4707_AT1 and 4718_AT1 and 4716_AT1 and 4725_AT1) or (4716_AT1 and 4725_AT1 and 4726_AT1 and 4696_AT1 and 4694_AT1 and 4718_AT1 and 4707_AT1 and 4537_AT1 and 4731_AT2 and 4705_AT1 and 4704_AT1 and 4722_AT1 and 4536_AT1 and 51079_AT1 and 7991_AT1 and 374291_AT1 and 4697_AT1 and 4709_AT1 and 4729_AT1 and 4695_AT1 and 55967_AT1 and 4708_AT1 and 4720_AT1 and 4728_AT1 and 4719_AT1 and 4701_AT1 and 4724_AT1 and 4698_AT1 and 4540_AT1 and 4717_AT1 and 126328_AT1 and 4538_AT1 and 4700_AT1 and 4715_AT1 and 4710_AT1 and 4712_AT1 and 4706_AT1 and 4541_AT1 and 4711_AT1 and 4702_AT1 and 4535_AT1 and 4539_AT1 and 4714_AT1 and 4723_AT1 and 4713_AT1) or (4711_AT1 and 4541_AT1 and 4706_AT1 and 4731_AT1 and 4535_AT1 and 4539_AT1 and 4702_AT1 and 4700_AT1 and 4710_AT1 and 4715_AT1 and 4723_AT1 and 4713_AT1 and 4714_AT1 and 4719_AT1 and 4717_AT1 and 126328_AT1 and 4540_AT1 and 4538_AT1 and 4724_AT1 and 4701_AT1 and 4698_AT1 and 4729_AT1 and 55967_AT1 and 4695_AT1 and 4697_AT1 and 4709_AT1 and 4728_AT1 and 4708_AT1 and 4720_AT1 and 4696_AT1 and 4726_AT1 and 4718_AT1 and 4707_AT1 and 4694_AT1 and 4725_AT1 and 4716_AT1 and 4712_AT2 and 4536_AT1 and 4722_AT1 and 7991_AT1 and 374291_AT1 and 51079_AT1 and 4705_AT1 and 4704_AT1 and 4537_AT1)", +"subsystem":"Oxidative Phosphorylation", +"notes":{ +"original_bigg_ids":[ +"NADH2_u10m" +] +} +}, +{ +"id":"NADHtpu", +"name":"NADH transporter, peroxisome", +"metabolites":{ +"nadh_c":-1.0, +"nadh_x":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Peroxisomal", +"notes":{ +"original_bigg_ids":[ +"NADHtpu" +] +} +}, +{ +"id":"NADHtru", +"name":"NADH transporter, endoplasmic reticulum", +"metabolites":{ +"nadh_c":-1.0, +"nadh_r":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Endoplasmic Reticular", +"notes":{ +"original_bigg_ids":[ +"NADHtru" +] +} +}, +{ +"id":"NADK", +"name":"NAD kinase", +"metabolites":{ +"adp_c":1.0, +"atp_c":-1.0, +"h_c":1.0, +"nad_c":-1.0, +"nadp_c":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"65220_AT1", +"subsystem":"NAD Metabolism", +"notes":{ +"original_bigg_ids":[ +"NADK" +] +} +}, +{ +"id":"NADN", +"name":"NAD nucleosidase", +"metabolites":{ +"adprib_c":1.0, +"h2o_c":-1.0, +"h_c":1.0, +"nad_c":-1.0, +"ncam_c":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"NAD Metabolism", +"notes":{ +"original_bigg_ids":[ +"NADN" +] +} +}, +{ +"id":"NADNe", +"name":"NAD nucleosidase,extracellular", +"metabolites":{ +"adprib_e":1.0, +"h2o_e":-1.0, +"h_e":1.0, +"nad_e":-1.0, +"ncam_e":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"952_AT1", +"subsystem":"NAD Metabolism", +"notes":{ +"original_bigg_ids":[ +"NADNe" +] +} +}, +{ +"id":"NADPHtru", +"name":"NADPH transporter, endoplasmic reticulum", +"metabolites":{ +"nadph_c":-1.0, +"nadph_r":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Endoplasmic Reticular", +"notes":{ +"original_bigg_ids":[ +"NADPHtru" +] +} +}, +{ +"id":"NADPHtxu", +"name":"NADPH transport, glyoxysome", +"metabolites":{ +"nadph_c":-1.0, +"nadph_x":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Peroxisomal", +"notes":{ +"original_bigg_ids":[ +"NADPHtxu" +] +} +}, +{ +"id":"NADPN", +"name":"NADP nucleosidase", +"metabolites":{ +"adprbp_c":1.0, +"h2o_c":-1.0, +"h_c":1.0, +"nadp_c":-1.0, +"ncam_c":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"NAD Metabolism", +"notes":{ +"original_bigg_ids":[ +"NADPN" +] +} +}, +{ +"id":"NADPNe", +"name":"NADP nucleosidase,extracellular", +"metabolites":{ +"adprbp_e":1.0, +"h2o_e":-1.0, +"h_e":1.0, +"nadp_e":-1.0, +"ncam_e":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"952_AT1", +"subsystem":"NAD Metabolism", +"notes":{ +"original_bigg_ids":[ +"NADPNe" +] +} +}, +{ +"id":"NADPtru", +"name":"NADP transporter, endoplasmic reticulum", +"metabolites":{ +"nadp_c":1.0, +"nadp_r":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Endoplasmic Reticular", +"notes":{ +"original_bigg_ids":[ +"NADPtru" +] +} +}, +{ +"id":"NADPtxu", +"name":"NADP transport, glyoxysome", +"metabolites":{ +"nadp_c":1.0, +"nadp_x":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Peroxisomal", +"notes":{ +"original_bigg_ids":[ +"NADPtxu" +] +} +}, +{ +"id":"NADS2", +"name":"Nicotinate-mononucleotide adenylyltransferase", +"metabolites":{ +"amp_c":1.0, +"atp_c":-1.0, +"dnad_c":-1.0, +"gln__L_c":-1.0, +"glu__L_c":1.0, +"h2o_c":-1.0, +"h_c":1.0, +"nad_c":1.0, +"ppi_c":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"55191_AT1", +"subsystem":"NAD Metabolism", +"notes":{ +"original_bigg_ids":[ +"NADS2" +] +} +}, +{ +"id":"NADtn", +"name":"NAD transport nuclear through pores", +"metabolites":{ +"nad_c":1.0, +"nad_n":-1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Nuclear", +"notes":{ +"original_bigg_ids":[ +"NADtn" +] +} +}, +{ +"id":"NADtpu", +"name":"NAD transporter, peroxisome", +"metabolites":{ +"nadh_c":1.0, +"nadh_x":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Peroxisomal", +"notes":{ +"original_bigg_ids":[ +"NADtpu" +] +} +}, +{ +"id":"NADtru", +"name":"NAD transporter, endoplasmic reticulum", +"metabolites":{ +"nad_c":1.0, +"nad_r":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Endoplasmic Reticular", +"notes":{ +"original_bigg_ids":[ +"NADtru" +] +} +}, +{ +"id":"NAGA2ly", +"name":"N-acetylgalactosaminidase, alpha-", +"metabolites":{ +"Ser_Thr_l":1.0, +"Tn_antigen_l":-1.0, +"h_l":-1.0, +"udp_l":-1.0, +"udpacgal_l":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"4668_AT1", +"subsystem":"Keratan sulfate degradation", +"notes":{ +"original_bigg_ids":[ +"NAGA2ly" +] +} +}, +{ +"id":"NAGAlby", +"name":"N-acetylgalactosaminidase, beta-", +"metabolites":{ +"acgbgbside_hs_l":-1.0, +"gbside_hs_l":1.0, +"h_l":-1.0, +"udp_l":-1.0, +"udpacgal_l":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Sphingolipid Metabolism", +"notes":{ +"original_bigg_ids":[ +"NAGAlby" +] +} +}, +{ +"id":"NAGAly", +"name":"N-acetylgalactosaminidase, alpha-", +"metabolites":{ +"acgagbside_hs_l":-1.0, +"gbside_hs_l":1.0, +"h_l":-1.0, +"udp_l":-1.0, +"udpacgal_l":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"4668_AT1", +"subsystem":"Sphingolipid Metabolism", +"notes":{ +"original_bigg_ids":[ +"NAGAly" +] +} +}, +{ +"id":"NAGLCAly", +"name":"N-acetylglucosaminidase, lysosomal", +"metabolites":{ +"Tn_antigen_l":1.0, +"acgam_l":1.0, +"core6_l":-1.0, +"h2o_l":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Keratan sulfate degradation", +"notes":{ +"original_bigg_ids":[ +"NAGLCAly" +] +} +}, +{ +"id":"NAHCO3_HCLt", +"name":"Bicarbonate transport (HCl/NaHCO3 exchange)", +"metabolites":{ +"cl_c":-1.0, +"cl_e":1.0, +"h_c":-1.0, +"h_e":1.0, +"hco3_c":1.0, +"hco3_e":-1.0, +"na1_c":1.0, +"na1_e":-1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"57282_AT1 or 9498_AT1", +"subsystem":"Transport, Extracellular", +"notes":{ +"original_bigg_ids":[ +"NAHCO3_HCLt" +] +} +}, +{ +"id":"NAIt", +"name":"Na+ / iodide cotransport", +"metabolites":{ +"i_c":1.0, +"i_e":-1.0, +"na1_c":2.0, +"na1_e":-2.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"6528_AT1", +"subsystem":"Transport, Extracellular", +"notes":{ +"original_bigg_ids":[ +"NAIt" +] +} +}, +{ +"id":"NAt", +"name":"Sodium transport (uniport)", +"metabolites":{ +"na1_c":1.0, +"na1_e":-1.0 +}, 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5279_AT2 and 5277_AT3 and 5283_AT1 and 51227_AT2) or (51227_AT3 and 5283_AT1 and 8818_AT1 and 5279_AT1 and 5277_AT1 and 9091_AT1) or (5279_AT2 and 8818_AT1 and 5277_AT1 and 9091_AT2 and 51227_AT3 and 5283_AT1) or (5277_AT3 and 5283_AT1 and 9091_AT2 and 51227_AT1 and 5279_AT1 and 8818_AT1) or (5277_AT3 and 5283_AT1 and 51227_AT2 and 9091_AT1 and 5279_AT1 and 8818_AT2) or (8818_AT1 and 5279_AT1 and 5277_AT2 and 9091_AT2 and 5283_AT1 and 51227_AT3) or (5277_AT2 and 9091_AT1 and 5279_AT1 and 8818_AT1 and 51227_AT2 and 5283_AT1) or (51227_AT3 and 5283_AT1 and 5279_AT2 and 8818_AT1 and 9091_AT1 and 5277_AT1) or (5277_AT3 and 9091_AT2 and 5283_AT1 and 51227_AT2 and 5279_AT1 and 8818_AT2) or (5283_AT1 and 9091_AT2 and 51227_AT1 and 5277_AT2 and 5279_AT1 and 8818_AT2) or (8818_AT2 and 9091_AT1 and 5279_AT1 and 5277_AT2 and 51227_AT1 and 5283_AT1) or (5277_AT2 and 9091_AT1 and 5279_AT2 and 8818_AT1 and 5283_AT1 and 51227_AT1) or (8818_AT2 and 9091_AT1 and 5279_AT1 and 5277_AT1 and 51227_AT1 and 5283_AT1) or (5277_AT1 and 5279_AT2 and 8818_AT2 and 51227_AT2 and 9091_AT2 and 5283_AT1) or (8818_AT1 and 5279_AT2 and 5277_AT2 and 9091_AT1 and 51227_AT2 and 5283_AT1) or (5277_AT3 and 5283_AT1 and 51227_AT1 and 8818_AT2 and 9091_AT1 and 5279_AT1) or (9091_AT2 and 51227_AT1 and 5283_AT1 and 5277_AT2 and 5279_AT2 and 8818_AT1) or (5279_AT2 and 8818_AT2 and 9091_AT1 and 5277_AT1 and 5283_AT1 and 51227_AT1) or (5277_AT3 and 51227_AT1 and 5283_AT1 and 9091_AT2 and 5279_AT2 and 8818_AT2) or (5283_AT1 and 9091_AT2 and 51227_AT3 and 5277_AT3 and 8818_AT2 and 5279_AT2) or (5277_AT3 and 5283_AT1 and 51227_AT2 and 9091_AT1 and 5279_AT2 and 8818_AT1) or (8818_AT1 and 5279_AT2 and 9091_AT1 and 5277_AT2 and 51227_AT3 and 5283_AT1) or (5277_AT1 and 5279_AT1 and 8818_AT2 and 9091_AT2 and 5283_AT1 and 51227_AT2) or (8818_AT1 and 9091_AT1 and 5279_AT1 and 51227_AT1 and 5283_AT1 and 5277_AT3) or (5283_AT1 and 51227_AT3 and 9091_AT2 and 5277_AT3 and 8818_AT1 and 5279_AT1) or (9091_AT1 and 8818_AT1 and 5279_AT2 and 51227_AT1 and 5277_AT3 and 5283_AT1) or (51227_AT1 and 5283_AT1 and 9091_AT2 and 8818_AT2 and 5277_AT1 and 5279_AT1) or (5279_AT1 and 5277_AT1 and 9091_AT1 and 8818_AT2 and 5283_AT1 and 51227_AT3) or (8818_AT1 and 5279_AT1 and 5277_AT2 and 9091_AT2 and 5283_AT1 and 51227_AT1) or (5283_AT1 and 51227_AT3 and 5277_AT2 and 9091_AT1 and 5279_AT1 and 8818_AT1) or (5283_AT1 and 51227_AT1 and 8818_AT1 and 5277_AT1 and 5279_AT1 and 9091_AT1) or (9091_AT2 and 5277_AT3 and 51227_AT1 and 5283_AT1 and 8818_AT1 and 5279_AT2) or (51227_AT3 and 5283_AT1 and 9091_AT2 and 5277_AT2 and 8818_AT1 and 5279_AT2) or (5277_AT2 and 9091_AT1 and 5279_AT1 and 8818_AT2 and 51227_AT3 and 5283_AT1) or (5283_AT1 and 51227_AT1 and 5277_AT2 and 9091_AT1 and 5279_AT1 and 8818_AT1) or (8818_AT1 and 9091_AT1 and 5279_AT1 and 5277_AT2 and 5283_AT1 and 51227_AT2) or (5277_AT2 and 5279_AT2 and 8818_AT1 and 51227_AT2 and 5283_AT1 and 9091_AT2) or (5279_AT2 and 8818_AT1 and 9091_AT1 and 5277_AT3 and 5283_AT1 and 51227_AT3) or (5283_AT1 and 5277_AT3 and 51227_AT3 and 5279_AT2 and 8818_AT2 and 9091_AT1) or (5279_AT2 and 8818_AT1 and 51227_AT3 and 5277_AT3 and 9091_AT2 and 5283_AT1) or (5279_AT1 and 5277_AT2 and 8818_AT2 and 51227_AT3 and 5283_AT1 and 9091_AT2) or (8818_AT1 and 5277_AT1 and 5279_AT1 and 9091_AT2 and 51227_AT1 and 5283_AT1) or (9091_AT1 and 5277_AT1 and 8818_AT1 and 5279_AT2 and 5283_AT1 and 51227_AT1) or (5283_AT1 and 51227_AT2 and 5279_AT1 and 9091_AT1 and 5277_AT1 and 8818_AT2) or (5277_AT2 and 8818_AT2 and 5279_AT2 and 9091_AT2 and 5283_AT1 and 51227_AT2) or (51227_AT1 and 5283_AT1 and 5279_AT2 and 8818_AT2 and 5277_AT2 and 9091_AT1)", +"subsystem":"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis", +"notes":{ +"original_bigg_ids":[ +"PIACGT" +] +} +}, +{ +"id":"PIK3", +"name":"Phosphatidylinositol 3-kinase", +"metabolites":{ +"adp_c":1.0, +"atp_c":-1.0, +"h_c":1.0, +"pail3p_hs_c":1.0, +"pail_hs_c":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"(5296_AT1 and 5293_AT1) or (5296_AT1 and 5291_AT1) or (5290_AT1 and 5295_AT1) or (8503_AT1 and 5290_AT1) or (23533_AT1 and 5294_AT1) or (5295_AT2 and 5291_AT1) or (5295_AT3 and 5291_AT1) or (5295_AT3 and 5290_AT1) or (5295_AT2 and 5293_AT1) or (5296_AT1 and 5290_AT1) or 5287_AT1 or (10870_AT1 and 5294_AT1) or 5286_AT1 or (5291_AT1 and 8503_AT1) or (5293_AT1 and 8503_AT1) or 5289_AT1 or (5295_AT1 and 5291_AT1) or 5288_AT1 or (5295_AT3 and 5293_AT1) or (5290_AT1 and 5295_AT2) or (5293_AT1 and 5295_AT1)", +"subsystem":"Inositol Phosphate Metabolism", +"notes":{ +"original_bigg_ids":[ +"PIK3" +] +} +}, +{ +"id":"PIK3er", +"name":"Phosphatidylinositol 3-kinase, endoplasmic reticulum", +"metabolites":{ +"adp_r":1.0, +"atp_r":-1.0, +"h_r":1.0, +"pail3p_hs_r":1.0, +"pail_hs_r":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"5287_AT1", +"subsystem":"Inositol Phosphate Metabolism", +"notes":{ +"original_bigg_ids":[ +"PIK3er" +] +} +}, +{ +"id":"PIK3n", +"name":"Phosphatidylinositol 3-kinase, nuclear", +"metabolites":{ +"adp_n":1.0, +"atp_n":-1.0, +"h_n":1.0, +"pail3p_hs_n":1.0, +"pail_hs_n":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Inositol Phosphate Metabolism", +"notes":{ +"original_bigg_ids":[ +"PIK3n" +] +} +}, +{ +"id":"PIK4", +"name":"Phosphatidylinositol 4-kinase", +"metabolites":{ +"adp_c":1.0, +"atp_c":-1.0, +"h_c":1.0, +"pail4p_hs_c":1.0, +"pail_hs_c":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"55361_AT1 or 5297_AT1 or 5298_AT1", +"subsystem":"Glycerophospholipid Metabolism", +"notes":{ +"original_bigg_ids":[ +"PIK4" +] +} +}, +{ +"id":"PIK4n", +"name":"Phosphatidylinositol 4-kinase, nuclear", +"metabolites":{ +"adp_n":1.0, +"atp_n":-1.0, +"h_n":1.0, +"pail4p_hs_n":1.0, +"pail_hs_n":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Inositol Phosphate Metabolism", +"notes":{ +"original_bigg_ids":[ +"PIK4n" +] +} +}, +{ +"id":"PIK5", +"name":"Phosphatidylinositol 5-kinase", +"metabolites":{ +"adp_c":1.0, +"atp_c":-1.0, +"h_c":1.0, +"pail5p_hs_c":1.0, +"pail_hs_c":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"23396_AT1 or 8394_AT1 or 8395_AT1", +"subsystem":"Inositol Phosphate Metabolism", +"notes":{ +"original_bigg_ids":[ +"PIK5" +] +} +}, +{ +"id":"PIK5n", +"name":"Phosphatidylinositol 5-kinase, nuclear", +"metabolites":{ +"adp_n":1.0, +"atp_n":-1.0, +"h_n":1.0, +"pail5p_hs_n":1.0, +"pail_hs_n":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Inositol Phosphate Metabolism", +"notes":{ +"original_bigg_ids":[ +"PIK5n" +] +} +}, +{ +"id":"PIPLC", +"name":"Phosphatidylinositol phospholipase C", +"metabolites":{ +"dag_hs_c":1.0, +"h2o_c":-1.0, +"h_c":1.0, +"mi1p__D_c":1.0, +"pail_hs_c":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"84812_AT1 or 5335_AT1 or 5336_AT1 or 5332_AT2 or 23236_AT2 or 51196_AT1 or 5331_AT1 or 9651_AT1 or 89869_AT1 or 5332_AT1 or 113026_AT1 or 5335_AT2 or 5330_AT1 or 23236_AT1 or 257068_AT1 or 23007_AT1 or 5333_AT1 or 5334_AT1", +"subsystem":"Inositol Phosphate Metabolism", +"notes":{ +"original_bigg_ids":[ +"PIPLC" +] +} +}, +{ +"id":"PIPLCn", +"name":"Phosphatidylinositol phospholipase C, nucleus", +"metabolites":{ +"dag_hs_n":1.0, +"h2o_n":-1.0, +"h_n":1.0, +"mi1p__D_n":1.0, +"pail_hs_n":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"23236_AT2 or 23236_AT1", +"subsystem":"Inositol Phosphate Metabolism", +"notes":{ +"original_bigg_ids":[ +"PIPLCn" +] +} +}, +{ +"id":"PIt2m", +"name":"Phosphate transporter mitochondrial", +"metabolites":{ +"h_c":-1.0, +"h_m":1.0, +"pi_c":-1.0, +"pi_m":1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"5250_AT3 or 5250_AT4 or 5250_AT1 or 5250_AT2", +"subsystem":"Transport, Mitochondrial", +"notes":{ +"original_bigg_ids":[ +"PIt2m" +] +} +}, +{ +"id":"PIt7_copy1", +"name":"Phosphate transport in/out via three Na+ symporter", +"metabolites":{ +"na1_c":3.0, +"na1_e":-3.0, +"pi_c":1.0, +"pi_e":-1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"10568_AT1 or 6569_AT1", +"subsystem":"Transport, Extracellular", +"notes":{ +"original_bigg_ids":[ +"PIt7", +"PIt7ir" +] +} +}, +{ +"id":"PIt7_copy2", +"name":"Phosphate transport in/out via three Na+ symporter", +"metabolites":{ +"na1_c":3.0, +"na1_e":-3.0, +"pi_c":1.0, +"pi_e":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"6568_AT1 or 10786_AT1 or 10050_AT1 or 10246_AT1", +"subsystem":"Transport, Extracellular", +"notes":{ +"original_bigg_ids":[ +"PIt7", +"PIt7ir" +] +} +}, +{ +"id":"PIt8", +"name":"Phosphate transport in/out via Na+ symporter", +"metabolites":{ +"na1_c":1.5, +"na1_e":-1.5, +"pi_c":1.0, +"pi_e":-1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"6575_AT1 or 6574_AT1", +"subsystem":"Transport, Extracellular", +"notes":{ +"original_bigg_ids":[ +"PIt8" +] +} +}, +{ +"id":"PIt9", +"name":"Phosphate transport in/out via two Na+ symporter", +"metabolites":{ +"na1_c":2.0, +"na1_e":-2.0, +"pi_c":1.0, +"pi_e":-1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"142680_AT1", +"subsystem":"Transport, Extracellular", +"notes":{ +"original_bigg_ids":[ +"PIt9" +] +} +}, +{ +"id":"PIter", +"name":"Phosphate transport, endoplasmic reticulum", +"metabolites":{ +"pi_c":1.0, +"pi_r":-1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"2544_AT1", +"subsystem":"Transport, Endoplasmic Reticular", +"notes":{ +"original_bigg_ids":[ +"PIter" +] +} +}, +{ +"id":"PItg", +"name":"Phosphate transport, Golgi apparatus", +"metabolites":{ +"pi_c":1.0, +"pi_g":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Golgi Apparatus", +"notes":{ +"original_bigg_ids":[ +"PItg" +] +} +}, +{ +"id":"PItn", +"name":"Phosphate transport, nuclear", +"metabolites":{ +"pi_c":1.0, +"pi_n":-1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Nuclear", +"notes":{ +"original_bigg_ids":[ +"PItn" +] +} +}, +{ +"id":"PItx", +"name":"Phosphate transporter, peroxisome", +"metabolites":{ +"pi_c":-1.0, +"pi_x":1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Transport, Peroxisomal", +"notes":{ +"original_bigg_ids":[ +"PItx" +] +} +}, +{ +"id":"PLA2", +"name":"Phospholipase A2", +"metabolites":{ +"Rtotal2_c":1.0, +"ak2gchol_hs_c":-1.0, +"ak2lgchol_hs_c":1.0, +"h2o_c":-1.0, +"h_c":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"", +"subsystem":"Glycerophospholipid Metabolism", +"notes":{ +"original_bigg_ids":[ +"PLA2" +] +} +}, +{ +"id":"PLA2_2", +"name":"Phospholipase A2", +"metabolites":{ +"Rtotal2_c":1.0, +"h2o_c":-1.0, +"h_c":1.0, +"lpchol_hs_c":1.0, +"pchol_hs_c":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"5320_AT1 or 8398_AT1 or 8398_AT2", +"subsystem":"Glycerophospholipid Metabolism", +"notes":{ +"original_bigg_ids":[ +"PLA2_2" +] +} +}, +{ +"id":"PLA2_2e", +"name":"Phospholipase A2", +"metabolites":{ +"Rtotal2_e":1.0, +"h2o_e":-1.0, +"h_e":1.0, +"lpchol_hs_e":1.0, +"pchol_hs_e":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"30814_AT1 or 81579_AT1 or 5320_AT1 or 26279_AT1 or 5319_AT1 or 8399_AT1 or 5322_AT1 or 64600_AT1", +"subsystem":"Glycerophospholipid Metabolism", +"notes":{ +"original_bigg_ids":[ +"PLA2_2e" +] +} +}, +{ +"id":"PLYSPSer", +"name":"Protein lysine peptidase (endoplasmic reticulum)", +"metabolites":{ +"Ntmelys_r":-1.0, +"h2o_r":-1.0, +"pepslys_r":1.0, +"tmlys_r":1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"9789_AT1 and 23478_AT1 and 60559_AT1 and 28972_AT1 and 90701_AT1", +"subsystem":"Lysine Metabolism", +"notes":{ +"original_bigg_ids":[ +"PLYSPSer" +] +} +}, +{ +"id":"PMANM", +"name":"Phosphomannomutase", +"metabolites":{ +"man1p_c":-1.0, +"man6p_c":1.0 +}, +"lower_bound":-999999.0, +"upper_bound":999999.0, +"gene_reaction_rule":"55276_AT1 or 5373_AT1 or 5372_AT1", +"subsystem":"Fructose and Mannose Metabolism", +"notes":{ +"original_bigg_ids":[ +"PMANM" +] +} +}, +{ +"id":"PMEVKx", +"name":"Phosphomevalonate kinase", +"metabolites":{ +"5dpmev_x":1.0, +"5pmev_x":-1.0, +"adp_x":1.0, +"atp_x":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, +"gene_reaction_rule":"10654_AT1", +"subsystem":"Cholesterol Metabolism", +"notes":{ +"original_bigg_ids":[ +"PMEVKx" +] +} +}, +{ +"id":"PMI12346PH", +"name":"5 diphosphoinositol 1 2 3 4 6 pentakisphosphate diphosphohydrolase", +"metabolites":{ +"h2o_c":-1.0, +"h_c":1.0, +"minohp_c":1.0, +"pi_c":1.0, +"ppmi12346p_c":-1.0 +}, +"lower_bound":0.0, +"upper_bound":999999.0, 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