diff --git a/packages/react-dom/src/__tests__/ReactDOM-test.js b/packages/react-dom/src/__tests__/ReactDOM-test.js
index ff829654454..dc70b16138a 100644
--- a/packages/react-dom/src/__tests__/ReactDOM-test.js
+++ b/packages/react-dom/src/__tests__/ReactDOM-test.js
@@ -477,6 +477,26 @@ describe('ReactDOM', () => {
     }
   });
 
+  it('should suppress DevTools console message when __REACT_DEVTOOLS_HIDE_CONSOLE__ is set', () => {
+    try {
+      global.__REACT_DEVTOOLS_HIDE_CONSOLE__ = true;
+      jest.resetModules();
+
+      const infoSpy = jest.spyOn(console, 'info').mockImplementation(() => {});
+
+      require('react-dom/client');
+
+      const devToolsMessage = infoSpy.mock.calls.find(call =>
+        call[0]?.includes?.('Download the React DevTools'),
+      );
+      expect(devToolsMessage).toBeUndefined();
+
+      infoSpy.mockRestore();
+    } finally {
+      delete global.__REACT_DEVTOOLS_HIDE_CONSOLE__;
+    }
+  });
+
   it('should not crash calling findDOMNode inside a function component', async () => {
     class Component extends React.Component {
       render() {
diff --git a/packages/react-dom/src/client/ReactDOMClient.js b/packages/react-dom/src/client/ReactDOMClient.js
index 9a9f3157b82..90ebf66353c 100644
--- a/packages/react-dom/src/client/ReactDOMClient.js
+++ b/packages/react-dom/src/client/ReactDOMClient.js
@@ -54,7 +54,14 @@ export {ReactVersion as version, createRoot, hydrateRoot};
 const foundDevTools = injectIntoDevTools();
 
 if (__DEV__) {
-  if (!foundDevTools && canUseDOM && window.top === window.self) {
+  if (
+    !foundDevTools &&
+    canUseDOM &&
+    window.top === window.self &&
+    // Allow suppressing this message via __REACT_DEVTOOLS_HIDE_CONSOLE__ in
+    // environments like CEP or nwjs where the DevTools extension cannot be installed.
+    typeof __REACT_DEVTOOLS_HIDE_CONSOLE__ === 'undefined'
+  ) {
     // If we're in Chrome or Firefox, provide a download link if not installed.
     if (
       (navigator.userAgent.indexOf('Chrome') > -1 &&
diff --git a/packages/react-dom/src/client/ReactDOMClientFB.js b/packages/react-dom/src/client/ReactDOMClientFB.js
index 872a4550aa3..305aa5a8591 100644
--- a/packages/react-dom/src/client/ReactDOMClientFB.js
+++ b/packages/react-dom/src/client/ReactDOMClientFB.js
@@ -150,7 +150,14 @@ Internals.Events /* Events */ = [
 const foundDevTools = injectIntoDevTools();
 
 if (__DEV__) {
-  if (!foundDevTools && canUseDOM && window.top === window.self) {
+  if (
+    !foundDevTools &&
+    canUseDOM &&
+    window.top === window.self &&
+    // Allow suppressing this message via __REACT_DEVTOOLS_HIDE_CONSOLE__ in
+    // environments like CEP or nwjs where the DevTools extension cannot be installed.
+    typeof __REACT_DEVTOOLS_HIDE_CONSOLE__ === 'undefined'
+  ) {
     // If we're in Chrome or Firefox, provide a download link if not installed.
     if (
       (navigator.userAgent.indexOf('Chrome') > -1 &&
diff --git a/scripts/flow/environment.js b/scripts/flow/environment.js
index 180ee3838de..5fd781443f6 100644
--- a/scripts/flow/environment.js
+++ b/scripts/flow/environment.js
@@ -17,6 +17,8 @@ declare const __REACT_DEVTOOLS_GLOBAL_HOOK__: any; /*?{
   inject: ?((stuff: Object) => void)
 };*/
 
+declare const __REACT_DEVTOOLS_HIDE_CONSOLE__: void | true;
+
 declare const reportError: (error: mixed) => void;
 
 declare module 'create-react-class' {