How to fast the calculation of CalcDM

[Yukaixu666]

Dear URD Team,

I'm experiencing significant delays with calcDM when analyzing ~58,000 cells. My current command:
obj.urd <- calcDM(obj.urd, knn = 10, genes.use = obj.urd@var.genes)

I've already:

Reduced highly variable genes to 500
Lowered knn to 10
Tried basic parallel setup

Could you advise:

Optimal parameters for large datasets?
Proper way to enable multi-core processing?
Any progress tracking methods for calcDM?
Other optimization strategies?