Interpretation of log likelihood

[cgrace1978]

Dear Dr Pickrell,

I am currently using the FGWAS software which you developed, and have some questions:

1. Could you tell me how the ln(llk) value in the *.llk file is interpreted?
   a. For example we observed a ln(llk) value of 504 –does this correspond to a likelihood value of 504 to the base e or -504 to the base e?
2. In an analysis we are observing a ln(llk) value of greater than 43619.5. Is this a symptom of convergence issues: The dataset we are using does not have many strong signals.

Many Thanks,

Chris Grace

Bioinformatician
PROCARDIS Group
The Wellcome Trust Centre for Human Genetics
Roosevelt Drive, Oxford, OX3 7BN, United Kingdom