SSSOM will have a wild variety of all prefixes, some of which are in the obo context, others of which are not.
What is ok is to try and standardise the prefixes mapping sets pre-ingest using curies.standardize() command, but we always have to prefer the built-in curie maps over the obo_context when interpreting the mappings.
@anitacaron I know we talked about this dependency at some point, which may have been ok for a first prototype, but not for the full fledged API; the point of sssom mapping sets is that they spring their own mapping sets.
Can you share the part of the code that would need to be changed to get rid of the obo context dependency?