diff --git a/requirements.txt b/requirements.txt
index 0888228..716f0de 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,5 +1,5 @@
 biopython==1.73
 Click==7.0
 intervaltree==3.0.2
-numpy==1.16.3
+numpy==1.22.0
 sortedcontainers==2.1.0