Specificity and Sensitivity - arkers from non-missing/non-missing data

[domjacri]

Initialize_markers() has defaults for pct.1, pct.2 columns from Seurat::FindAllMarkers() -- if you are using a dataset/modality without missingness (spatial) or a method that corrects for sparsness (scVI --> using corrected model for markers), you will need to relax parameters:

Current recommendation: Initialize_markers(..., sens_thresh = 0, spec_thresh = 1)

[richardmustaklem]

Include this in the custom vignette @domjacri