diff --git a/src/NSubstitute/Core/DefaultForType.cs b/src/NSubstitute/Core/DefaultForType.cs
index f1fde93a..d20909fc 100644
--- a/src/NSubstitute/Core/DefaultForType.cs
+++ b/src/NSubstitute/Core/DefaultForType.cs
@@ -46,6 +46,15 @@ private object DefaultInstanceOfValueType(Type returnType)
             return BoxedDouble;
         }
 
-        return Activator.CreateInstance(returnType)!;
+        // Need to have a special case for Nullable<T> to return null.
+        if (returnType.IsGenericType && returnType.GetGenericTypeDefinition() == typeof(Nullable<>))
+        {
+            return null!;
+        }
+#if NET5_0_OR_GREATER
+        return System.Runtime.CompilerServices.RuntimeHelpers.GetUninitializedObject(returnType);
+#else
+        return System.Runtime.Serialization.FormatterServices.GetUninitializedObject(returnType);
+#endif
     }
 }
\ No newline at end of file
diff --git a/src/NSubstitute/Routing/AutoValues/AutoObservableProvider.cs b/src/NSubstitute/Routing/AutoValues/AutoObservableProvider.cs
index 713a5bde..8d768534 100644
--- a/src/NSubstitute/Routing/AutoValues/AutoObservableProvider.cs
+++ b/src/NSubstitute/Routing/AutoValues/AutoObservableProvider.cs
@@ -21,6 +21,7 @@ public bool CanProvideValueFor(Type type) =>
 
     private static object? GetDefault(Type type)
     {
-        return type.GetTypeInfo().IsValueType ? Activator.CreateInstance(type) : null;
+        var defaultForType = new DefaultForType();
+        return defaultForType.GetDefaultFor(type);
     }
 }
diff --git a/src/NSubstitute/Routing/AutoValues/AutoTaskProvider.cs b/src/NSubstitute/Routing/AutoValues/AutoTaskProvider.cs
index 13d365f3..a7be528b 100644
--- a/src/NSubstitute/Routing/AutoValues/AutoTaskProvider.cs
+++ b/src/NSubstitute/Routing/AutoValues/AutoTaskProvider.cs
@@ -1,3 +1,4 @@
+using NSubstitute.Core;
 using System.Reflection;
 
 namespace NSubstitute.Routing.AutoValues;
@@ -32,6 +33,7 @@ public object GetValue(Type type)
 
     private static object? GetDefault(Type type)
     {
-        return type.GetTypeInfo().IsValueType ? Activator.CreateInstance(type) : null;
+        var defaultForType = new DefaultForType();
+        return defaultForType.GetDefaultFor(type);
     }
 }
diff --git a/tests/NSubstitute.Acceptance.Specs/ArgumentMatching.cs b/tests/NSubstitute.Acceptance.Specs/ArgumentMatching.cs
index b43ef848..b0b2a16b 100644
--- a/tests/NSubstitute.Acceptance.Specs/ArgumentMatching.cs
+++ b/tests/NSubstitute.Acceptance.Specs/ArgumentMatching.cs
@@ -866,6 +866,27 @@ public void Does_support_out_method_with_base_override()
         Assert.That(outArg, Is.EqualTo(4));
     }
 
+    [Test]
+    public void Any_on_struct_with_default_constructor_should_work()
+    {
+        var something = Substitute.For<IWithStructWithDefaultConstructor>();
+        Assert.DoesNotThrow(() => something.MethodWithStruct(Arg.Any<StructWithDefaultConstructor>()));
+    }
+
+    public struct StructWithDefaultConstructor
+    {
+        public int Value { get; set; }
+        public StructWithDefaultConstructor()
+        {
+            Value = 42;
+        }
+    }
+
+    public interface IWithStructWithDefaultConstructor
+    {
+        void MethodWithStruct(StructWithDefaultConstructor arg);
+    }
+
     [SetUp]
     public void SetUp()
     {