Check the following links: https://github.com/greglandrum/RSC_OpenScience_Standardization_202104/blob/main/Standardization%20and%20Validation%20with%20the%20RDKit.ipynb https://github.com/chembl/ChEMBL_Structure_Pipeline/wiki/Work-done-by-each-step https://github.com/rdkit/rdkit/issues/3998
