diff --git a/.changeset/solid-turkeys-shop.md b/.changeset/solid-turkeys-shop.md
new file mode 100644
index 00000000000..cbce371d3a4
--- /dev/null
+++ b/.changeset/solid-turkeys-shop.md
@@ -0,0 +1,5 @@
+---
+'@primer/react': patch
+---
+
+SelectPanel: Remove `usingRemoveActiveDescendant` usage from component
diff --git a/packages/react/src/SelectPanel/SelectPanel.tsx b/packages/react/src/SelectPanel/SelectPanel.tsx
index 8fe2e158fed..cd99fc00bc2 100644
--- a/packages/react/src/SelectPanel/SelectPanel.tsx
+++ b/packages/react/src/SelectPanel/SelectPanel.tsx
@@ -216,7 +216,6 @@ function Panel({
   const usingFullScreenOnNarrow = disableFullscreenOnNarrow ? false : featureFlagFullScreenOnNarrow
   const shouldOrderSelectedFirst =
     useFeatureFlag('primer_react_select_panel_order_selected_at_top') && showSelectedOptionsFirst
-  const usingRemoveActiveDescendant = useFeatureFlag('primer_react_select_panel_remove_active_descendant')
 
   // Single select modals work differently, they have an intermediate state where the user has selected an item but
   // has not yet confirmed the selection. This is the only time the user can cancel the selection.
@@ -755,8 +754,10 @@ function Panel({
       const hasModifier = event.ctrlKey || event.altKey || event.metaKey
       if (hasModifier) return
 
-      // skip if it's not a alphabet key
-      if (!isAlphabetKey(event.nativeEvent as KeyboardEvent)) return
+      // skip if it's not the forward slash or an alphabet key
+      if (event.key !== '/' && !isAlphabetKey(event.nativeEvent as KeyboardEvent)) {
+        return
+      }
 
       // if this is a typeahead event, don't propagate outside of menu
       event.stopPropagation()
@@ -794,7 +795,7 @@ function Panel({
                 }
               : {}),
           } as React.CSSProperties,
-          onKeyDown: usingRemoveActiveDescendant ? preventBubbling(overlayProps?.onKeyDown) : overlayProps?.onKeyDown,
+          onKeyDown: preventBubbling(overlayProps?.onKeyDown),
         }}
         focusTrapSettings={focusTrapSettings}
         focusZoneSettings={focusZoneSettings}