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Description
Under the assumptions that
- the structure factor amplitudes are normally distributed
- the phases are Von Mises (circularly normally) distributed
- all amplitudes and phases are independent
It is possible to show that the MLE for a difference map is
Assuming the phases come from a model,
Three points:
- this theory needs to be tested empirically
- if we employ a more sophisticated scheme, such as the one recommended by R. Read, if we should weight or not will depend on the final map
- we should be able to re-use code from the
ROCKETpipeline to estimatems
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