Input is the unit of rare variants within a gene (or a pathway) I assume?

[qserenali]

Since the genotype data does not need to have a header (or marker name), I assume that GV-GDT expects the user to break the data set into units for testing. So if one wants to test 20,000 genes, one would need to call rv-gdt 20,000 times?

[zhangyuan5422]

Hi,
I also have this question " if one wants to test 20,000 genes, one would need to call rv-gdt 20,000 times", do you have methods to deal with it?

Best,
Yuan