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sb0201 -- Integrase BxB1-His10 #1

@graik

Description

@graik
ID / Name
tentative ID sb0201
construct name Int-BxB1-His10-pJEx411c
benchling link construct sb0201 in sharedParts/recombinases
rotmic link construct link

What's the purpose of this construct?
Integrase expression construct. Primary goal is to establish an efficient protocol for sequential insertion of DNA fragments into a backbone for (1) bar-coding purposes and (2) combinatorial pathway assembly.

Discussion & Comments
Judging from literature BxB1 is, so far, the best-performing Serine recombinase for cloning purposes. It features fast kinetics and near 100% recombination efficiency without any excision activity.

Implementation Progress

  • sequence design
  • rotmic registration
  • primer / gene synthesis order
  • sequencing / quality control
  • sample registration of DNA and cell stock

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