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tirth1305/README.md

πŸ‘‹ Hi, I'm Tirth Patel

πŸŽ“ Bioinformatics Student | Machine Learning & Genomics Enthusiast
πŸ’» Department of Bioinformatics, Marwadi University
🌱 Exploring computational biology, transcriptomics, and AI-driven drug discovery


πŸš€ About Me

  • πŸ”¬ Passionate about integrating machine learning with biological data to solve real-world healthcare challenges.
  • 🧬 Researching antimicrobial resistance prediction, cancer genomics, and graph-based biological networks.
  • ☁️ Hands-on with Python, R, C#, SQL, Azure, and Streamlit.
  • πŸ’‘ I love designing data-driven bioinformatics pipelines β€” from raw sequencing to predictive modeling.
  • πŸŽ₯ Also a creative After Effects video editor (because science should look good too πŸ˜‰).

🧩 Projects

Machine learning-based pipeline for predicting antimicrobial resistance in Acinetobacter baumannii using k-mer genomic features.

Used Catboost with TCGA data to predict lung adenocarcinoma treatment outcomes.

🧫 Breast Cancer Pathway Analysis (KEGG)

Analyzed the PI3K-AKT signaling pathway for breast cancer progression and potential drug targets.

🧬 Prion Protein Structural Modeling

Molecular modeling and therapeutic site prediction using computational structural biology.


🧰 Tech Stack

Languages:
Python β€’ R β€’ C# β€’ SQL

Machine Learning:
scikit-learn β€’ XGBoost β€’ LightGBM β€’ Pandas β€’ NumPy

Bioinformatics Tools:
Biopython β€’ Scanpy β€’ KEGG API β€’ TCGA data β€’ BV-BRC

Visualization:
Matplotlib β€’ Seaborn β€’

Others:
GitHub β€’ Azure OpenAI β€’ Streamlit β€’ FAISS β€’ LangChain


πŸ† Highlights

  • πŸ§ͺ Built an ensemble ML model achieving ~80% accuracy in AMR prediction
  • 🧠 Applied feature selection & ensemble learning for biological datasets
  • πŸ“Š Experienced with omics data analysis, gene expression, and network biology
  • 🌐 Currently exploring Graph Neural Networks for antibiotic combination prediction

πŸ“« Connect with Me

πŸ“§ tirthq1@gmail.com
πŸ”— LinkedIn
πŸ’» GitHub


⭐ "Bridging biology and machine learning β€” one dataset at a time."

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