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Dear @tschuelia,
Thanks for the update on Pythia!
I was wondering if this (or the old) version of pythia can handle a concatenated alignment of nucleotides and aminoacid sequences? If not, separating the alignment and running pythia on the different parts doesn't seem like an option as I would expect each part of the alignment give me different information on the difficulty to analyse the data.
And another small question: I find quite a change on the difficulty score given by pythia 0.0 (score=0.5) and 2.0 (score=0.3), why can this be?
Thanks again!
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