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DBSVATstats

Calculation of VAT summary and subregion statistics

The calculation of summary VAT and subregion statisitics from files extracted within LEADDBS (http://www.lead-dbs.org/). Matlab software is required.

The codes here were initially performed upon 64 PD patients receiving DBS stimulation on the STN, as analysed in Mosley et al. (2018, Neuroimage: Clinical)

graphical abstract

The full citation if you find this package useful:

  • Mosley, PE, Smith, D, Coyne, T, Silburn, P, Breakspear, M, & Perry, A. (2018). The site of stimulation moderates neuropsychiatric symptoms after subthalamic deep brain stimulation for Parkinson's disease. NeuroImage: Clinical.

Contributers: Alistair Perry and Philip Mosley

We note these codes are to be used on files extracted after utilizing Lead DBS software. We hence acknowledge Lead DBS software and it's developers, as well as the Acolla and BigBrain datasets for providing open-source anatomical information that were implemented in the current study.

References:

Accolla, EA, Dukart, J, Helms, G, Weiskopf, N, Kherif, F, Lutti, A, ... & Draganski, B. (2014). Brain tissue properties differentiate between motor and limbic basal ganglia circuits. Human brain mapping, 35(10), 5083-5092.

Amunts K, Lepage C, Borgeat L, Mohlberg H, Dickscheid T, Rousseau M+, Bludau S, Bazin PL, Lewis LB, Oros-Peusquens AM, Shah NJ, Lippert T, Zilles K, Evans AC (2013) BigBrain: An ultrahigh-resolution 3D human brain model. Science, 340(6139): 1472-1475

Horn A, Kühn A. Lead-DBS: A toolbox for deep brain stimulation electrode localizations and visualizations. NeuroImage, 2014.

If any questions or opportunities to collaborate, please email either alistairgperry at gmail or p.mosley at uq.edu.au

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