InterTADs is an open-source tool written in R, for integrating multi-omics data (e.g. DNA methylation, expression, mutation) from the same physical source (e.g. patient) taking into account the chromatin configuration of the genome, i.e. the topologically associating domains (TADs).
You can simply clone the repository by using git:
git clone https://github.com/BiodataAnalysisGroup/InterTADs.git
The proposed method was evaluated on data from Chronic lymphocytic leukemia (DNA methylation and expression values). The datasets have been deposited in the ArrayExpress database at EMBL‐EBI under the accession numbers E‐MTAB‐6955 and E‐MTAB‐6962, respectively.
Pull requests are welcome. For major changes, please open an issue first to discuss what you would like to change.
This project is licensed under the MIT License - see the LICENSE file for details