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@akmanning akmanning commented Aug 3, 2022

Major changes from assoc-aggregate.wdl

workflow: assoc_agg_one_gds

  • The expected gds and variant_group_file are for a single chromosome
  • the Array[File] input_gds_files input was changed to File input_gds and likewise the Array[File] variant_group_files and variant_include_files was changed to File variant_group_file and variant_include_file
  • the scatter across chromosomes was removed
  • the sbg_prepare_segments_1 task is no longer necessary
  • scattering across the segments is now simplified to scatter over an integer array (based on the number of actual segments for the chromosome
  • added a default value for n_segments and n_segments must be between 1 and 10. The upper limit is arbitrary, but in order to make the segments feature work, n_segments is multiplied by 23 in the input to the define_segments.R
  • required aggregate_type, chromosome, test inputs

Task assoc_aggregate

  • simpler file inputs
  • Int segment is now used
  • the variant include file is calculated on the fly
  • fixed the default out_prefix so that the output files have the form label.chrN.segN.RData (that format is expected in task assoc_combine_r

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