SPLAT (Simultaneous Proteome Localization and Turnover) is a method to simultaneously quantify protein translocation and turnover rates in vivo. This repository provides a workflow to process tandem mass tag (TMT) and stable isotopic labeling by amino acids in cell culture (SILAC) mass spectrometry data generated in SPLAT experiments. The SPLAT method is described in detail in our preprint. Please see the Documentation page for more information.
The splat-workflow package can be installed via pip and will automatically install the
dependencies of splat. After installation, the splat command will be available in your path.
SPLAT requires the following software to be installed:
riana==0.7.1
pytmt=0.4.1
Please contact us if you wish to contribute, and submit pull requests to us.
- Edward Lau, PhD - ed-lau
- Jordan Currie, BSc - jordancurrie
This project is licensed under the MIT License - see the LICENSE.md file for details