I am Oluwaseun Ajayi, a Chemistry PhD Researcher at the University of Georgia, specializing in bioanalytical and materials chemistry, structural biology, enzymology, molecular biology, glycobiology, and computer-aided drug design (CADD) for enzyme and therapeutic research. I develop and implement robust, automated analytical and computational workflows for glycans, glycoproteins, antibodies, and complex biological systems, integrating high-resolution mass spectrometry, enzyme kinetics, structural biology, predictive modeling, and machine learning. My work emphasizes reproducibility, scalability, and data-driven decision-making, bridging experimental chemistry with software-enabled and automated laboratory workflows.

• Multiomics sample preparation and protein expression/purification
• PLP-dependent enzyme characterization
• High-performance liquid chromatography coupled with ion mobility mass spectrometry (HPLC-IM-MS)
• Liquid chromatography-tandem mass spectrometry (LC-MS/MS)
• High-resolution MS¹ profiling, Fast Protein Liquid Chromatography (FPLC), UV-Vis, Raman spectroscopy, and nuclear magnetic resonance spectroscopy
• Stopped-flow kinetics, X-ray crystallography, and cryo-electron microscopy workflows
• High-throughput assay development and automated analytical workflows

• Computer-Aided Drug Design (CADD): end-to-end workflows for enzyme and therapeutic design
• Molecular docking and molecular dynamics simulations
• MM/GBSA free-energy calculations, virtual screening, ligand optimization, and ADMET predictions
• Integration of computational modeling with experimental data for mechanistic insights

• Multidisciplinary research at the interface of chemical biology, structural enzymology, and computational modeling
• Molecular-level determinants of enzyme function and mechanism-driven therapeutic design
• Workflow automation, method development, and high-throughput analysis

Incoming Lab Automation Co-op at Johnson & Johnson – Cell Engineering and Analytical Sciences group

I will contribute to the deployment and operation of automated laboratory workcells, including robotic transport systems, control logic configuration, and workcell communication protocols.
The role combines hands-on experience with high-throughput automation, method development, and bio/chem/biochem laboratory workflows, emphasizing problem-solving, creative thinking, and technical execution.

Key Skills: Laboratory automation, robotic systems, liquid handling, workflow development, problem-solving

Experimental: HPLC-IM-MS, LC-MS/MS, FPLC, UV-Vis, Raman, NMR, X-ray crystallography, cryo-EM
Computational & CADD: Molecular docking, molecular dynamics simulations, MM/GBSA, virtual screening, ligand optimization, ADMET prediction, end-to-end computer-aided drug design workflows
Workflow & Automation: High-throughput assay development, automated analytical workflows, experimental-computational integration

I am open to collaborations involving analytical workflows, computational modeling, structural chemistry, method development, laboratory automation, and CADD-based research.

Email: seunolanikeajayi@gmail.com
LinkedIn: Oluwaseun Ajayi