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54 changes: 54 additions & 0 deletions data/offsides/meta.yaml
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---
name: offsides
description: |-
OffSIDES is a database of individual drug side effect
signals mined from the FDA's Adverse Event Reporting System. The
innovation of OffSIDES is that a propensity score matching (PSM) model
is used to identify control drugs and produce better PRR estimates. In
OffSIDES we focus on drug safety signals that are not already
established by being listed on the structured product label - hence
they are off-label drug side effects.
targets:
- id: PRR
description: proportional reporting ratio
type: continuous
names:
- proportional reporting ratio
- id: PRR_error
description: standard error of the PRR estimate
type: continuous
sample: false
names:
- standard error of the proportional reporting ratio error
- id: mean_reporting_frequency
description: mean reporting frequency for the drug
type: continuous
names:
- mean reporting frequency
identifier:
- id: drug_concept_name
description: RxNorm name string for the drug
type: categorical
- id: condition_concept_name
description: MedDRA identifier for the side effect
type: categorical
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this will need to use prompt templates, I guess, because they are not independent.

license: CC BY 4.0
links:
- url: https://tatonettilab.org/resources/nsides/
description: data source
- url: https://nsides.io/
description: database website
num_points: 2977338
bibtex: |-
@article{Tatonetti2012,
author = {Tatonetti, Nicholas P. and Ye, Peter P. and Daneshjou, Roxana and Altman, Russ B.},
title = {Data-driven prediction of drug effects and interactions},
journal = {Sci Transl Med},
volume = {4},
number = {125},
pages = {125ra31},
year = {2012},
doi = {10.1126/scitranslmed.3003377},
pmid = {22422992},
pmcid = {PMC3382018}
}
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