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The repository provides the source code for "A Deep Learning Approach for Fast Muscle Water T2 Mapping with Subject Specific Fat T2 Calibration from Multi-Spin-Echo Acquisitions"

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barma7/Deep_Learning_for_Muscle_T2_mapping

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Deep_Learning_for_Muscle_T2_mapping

The repository provides the source code for "A Deep Learning Approach for Fast Muscle Water T2 Mapping with Subject Specific Fat T2 Calibration from Multi-Spin-Echo Acquisitions"

Full citation: Barbieri, M., Hooijmans, M.T., Moulin, K. et al. A deep learning approach for fast muscle water T2 mapping with subject specific fat T2 calibration from multi-spin-echo acquisitions. Sci Rep 14, 8253 (2024). https://doi.org/10.1038/s41598-024-58812-2

Deep Learning Application

The deep learning application has been developed in TensorFlow. TensorFlow, Numpy, and Scipy are required to run the deep learning application.

The EPG code for simulating the Multi-Echo-Spin-Echo (MESE) data is provided in Matlab. The core EPG function is taken from the StimFit toolbox (https://github.com/usc-mrel/StimFit). Since the actual pulse shapes used by the vendors in implementing the MESE sequence are proprietary information, the simulations are provided for SINC pulses with TBW = 2.

The functions used to generate the excitation and refocusing pulses and respective slice profiles are provided and make use of the RF Pulse Design toolbox created by John Pauly (https://rsl.stanford.edu/research/software.html)

DATA

The raw MESE data (in NIfTI format) and processed data can be downloaded from Zenodo (https://doi.org/10.5281/zenodo.10520542)

Alternative T2 fitting methods

Conventional EPG fitting algorithms based on Dictionary and Non-Linear Lease-Squared (NLSQ) methods are also provided in Matlab.

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The repository provides the source code for "A Deep Learning Approach for Fast Muscle Water T2 Mapping with Subject Specific Fat T2 Calibration from Multi-Spin-Echo Acquisitions"

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