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The packages certifi, charset-normalizer, idna, and urllib3 are transitive dependencies of requests and cdisc-library-client. Pinning transitive dependencies in requirements.txt can lead to version conflicts and maintenance issues. Unless there's a specific security or compatibility reason, it's better to let pip resolve these automatically. Consider removing these entries and only specifying direct dependencies (cdisc-library-client, jsonata-python, python-dotenv, PyYAML, requests). If requests is only used indirectly through cdisc-library-client, you may also consider removing it.