Mathematical model of thermosensory neurons in C. elegans

This repository accompanies the analysis from and data used in the article: Batra, A., & Sharma, R. (2026). Neuronal decoding of temperature signals in Caenorhabditis elegans. Physical Review E. https://doi.org/10.1103/6qyt-79kr

Here the following files will be found:

• Code for numerically solving the model for cGMP signal transduction pathway in primary thermosensory neurons (AFD) in C. elegans: AFD_model.nb
• Temperature signal used in the model and its comparison to experiments: Signal_fit_model.ipynb
• Experimental data of linear thermal ramp signals: Shown in Excel File Data Signaldata_AFDExpts.xlsx
• Experimental data against which the model is validated: Fig3g_Huang_Calcium.csv