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🛠️ Mason: [Add Change Control Regulatory Impact Assessor]#582

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feat/strategic-genesis-change-control-assessor-17459061468396427450
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🛠️ Mason: [Add Change Control Regulatory Impact Assessor]#582
fderuiter wants to merge 2 commits intomainfrom
feat/strategic-genesis-change-control-assessor-17459061468396427450

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💡 What
Added a new expert-level prompt change_control_regulatory_impact_assessor.prompt.yaml within the prompts/regulatory/quality domain. It acts as a Principal Regulatory Affairs Change Control Architect to evaluate proposed medical device changes against jurisdictional frameworks (e.g., US FDA, EU MDR).

🎯 Why
Gap Analysis identified a critical void in the regulatory/quality ecosystem. While CAPA, complaints, and FDA 483 responses were addressed, there was no prompt dedicated to the rigorous, multi-jurisdictional regulatory impact assessment of proposed changes to marketed devices (a ubiquitous and high-risk task in QMS).

📊 Impact
Provides Quality and Regulatory professionals with a highly analytical, objective tool to explicitly determine if a change is 'Significant' (requiring submission) or 'Non-Significant' (requiring only a Letter to File), standardizing documentation and mitigating compliance risks.


PR created automatically by Jules for task 17459061468396427450 started by @fderuiter

Co-authored-by: google-labs-jules[bot] <161369871+google-labs-jules[bot]@users.noreply.github.com>
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@fderuiter fderuiter marked this pull request as ready for review March 18, 2026 23:59
Copilot AI review requested due to automatic review settings March 18, 2026 23:59
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Pull request overview

Adds a new expert prompt under prompts/regulatory/quality to assess regulatory impact of medical device change controls across multiple jurisdictions, and wires it into the repository’s overview and docs navigation.

Changes:

  • Introduces change_control_regulatory_impact_assessor.prompt.yaml with variables, structured XML-tagged output requirements, and basic evaluators.
  • Updates prompts/regulatory/quality/overview.md to list the new prompt.
  • Updates documentation indices (TOC + regulatory landing pages) and adds the generated prompt documentation page.

Reviewed changes

Copilot reviewed 6 out of 6 changed files in this pull request and generated 2 comments.

Show a summary per file
File Description
prompts/regulatory/quality/overview.md Adds the new prompt to the quality overview list.
prompts/regulatory/quality/change_control_regulatory_impact_assessor.prompt.yaml New change-control regulatory impact assessor prompt definition.
docs/table-of-contents.md Adds the new prompt doc page to the global docs TOC.
docs/regulatory.md Adds the new prompt link to the regulatory docs index.
docs/prompts/regulatory/quality/change_control_regulatory_impact_assessor.prompt.md Adds the generated documentation page for the new prompt.
docs/index.md Adds the new prompt link to the docs homepage prompt listing.

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Target Jurisdictions: {{jurisdictions}}
</input>
testData:
- input:
Comment on lines +74 to +79
testData:
- input:
device_description: "Class II (US) / Class IIb (EU) electro-surgical generator intended for cutting and coagulating tissue."
proposed_change: "Change in the main microcontroller unit (MCU) due to component obsolescence. The new MCU has the same core architecture but operates at a higher clock speed. Software requires a minor update to adjust timing loops, but no changes to the algorithm, GUI, or safety features."
jurisdictions: "US FDA, EU MDR"
expected: "1. Executive Summary"
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2 participants