Adverse Events Analyzer

A web-based tool for analyzing medical documents to identify adverse events, related medications, and relevant research articles.

Features

1. Document Analysis

• Upload and process PDF documents containing medical information
• Extract key medical entities:
  • Medications and drugs
  • Symptoms and side effects
  • Medical conditions and diseases
• Intelligent text processing with advanced NLP capabilities

2. Research Integration

• Automatic PubMed article search based on extracted information
• Relevant medical literature discovery
• Direct links to full articles on PubMed
• Smart filtering for case studies and adverse event reports

3. Smart Summarization

• Comprehensive case summaries
• Relationship analysis between medications and symptoms
• Key findings highlighting
• Clinical context integration

4. User Interface

• Modern, responsive design using Bootstrap 5
• Drag-and-drop file upload
• Real-time processing status indicators
• Clear visualization of results using cards
• Mobile-friendly layout

Technology Stack

• Frontend:

  • HTML5
  • CSS3 (Bootstrap 5.3.2)
  • JavaScript (ES6+)
  • Bootstrap Icons

• APIs:

  • Gemini API for text extraction and summarization
  • OpenAI API for PubMed search term generation
  • PubMed E-utilities for article retrieval

• Features:

  • PDF text extraction and base64 encoding
  • Medical entity recognition using LLMs
  • Smart PubMed search term generation
  • XML parsing for PubMed articles
  • Intelligent adverse event analysis
  • Real-time processing with status indicators

Getting Started

1. Clone the repository
2. Configure your API keys:
   • Set up Gemini API key
   • Set up OpenAI API key
3. Open index.html in a modern web browser
4. Enter your API keys in the configuration panel
5. Upload a medical document (PDF format)
6. Wait for the three-step analysis to complete:
   • Text extraction
   • Article search
   • Summary generation
7. Review the extracted information, related articles, and adverse event analysis

Project Structure

adverse-events/
├── index.html          # Main application page
├── script.js           # Main application logic
├── api-config.js       # API configuration and setup
├── xml-helper.js       # XML parsing utilities  
├── data/              # Data files
   └── npi.docx       # NPI guidelines

Browser Compatibility

• Chrome (latest)
• Firefox (latest)
• Safari (latest)
• Edge (latest)

Contributing

1. Fork the repository
2. Create a feature branch
3. Commit your changes
4. Push to the branch
5. Create a Pull Request

License

This project is licensed under the MIT License - see the LICENSE file for details.

Acknowledgments

• Google for Gemini API access
• OpenAI for GPT API access
• NCBI for PubMed E-utilities
• Bootstrap team for the UI framework