Add 500-protein human SwissProt subset for mhcquant SDRF test#1987
Merged
jonasscheid merged 1 commit intonf-core:mhcquantfrom Apr 14, 2026
Merged
Add 500-protein human SwissProt subset for mhcquant SDRF test#1987jonasscheid merged 1 commit intonf-core:mhcquantfrom
jonasscheid merged 1 commit intonf-core:mhcquantfrom
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mashehu
approved these changes
Apr 14, 2026
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Summary
Adds
testdata/UP000005640_9606_500prot.fasta, a 500-protein subset of the human SwissProt proteome (UP000005640), for use as the default FASTA in the upcomingtest_sdrfprofile in nf-core/mhcquant.Rationale
The current full proteome (
UP000005640_9606.fasta, 20,610 proteins) causes the CometAdapter step in the SDRF test to exceed the 6 GB CI memory cap or hit the 2 h wall-time when combined with unspecific cleavage on thePXD009752test RAW files.Benchmarking showed the 500-protein subset:
spectrum_batch_size=20000)Content
UP000005640_9606.fasta(deterministic head)Related
Used by nf-core/mhcquant#445 (SDRF/PRIDE input support).