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mhngr and others added 5 commits December 18, 2025 17:47
… candidate matching logic

- Implement functions to parse alleles, compute allele frequencies, and build an inverted index for efficient lookups.
- Introduce mutation checking and likelihood ratio calculations for parent-child relationships.
- Add pre-filtering of candidates based on shared rare alleles and mutation potential.
- Optimize match_single function to utilize caching for allele frequencies and inverted index, improving performance.
- Return top candidate matches sorted by combined likelihood ratio (CLR) with posterior probability calculations.
Added scalability to handle 500,000 data records
@tavallaie tavallaie merged commit ceac726 into main Dec 28, 2025
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@tavallaie tavallaie deleted the mhngr-main branch December 28, 2025 07:22
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2 participants