CIDP is a software for designing sgRNAs in CRISPR system.
So many sgRNA-design tools have been published. Most of them require users to select a closely-related species for completing the designing process.
However, there are still huge differences in sequences between the species of interest and the closely-related species. Not to mention that some researchers have difficulties in finding a closely-related species from the database of the sgRNA-design tools. The situation is particularly serious in plant research。
Therefore, we developed CIDP that allows users to build the database using the input genomic sequences instead of choosing a closely-related species. Furthermore, apart from designing sgRNAs, CIDP can perform the functions of designing primers and extracting required sequences from genome-sequence files.
CIDP is an open-source software. The source code will be published as soon as the related article has been accepted.
Please note: The software can be downloaded from the "Releases" of this website (on the right side). If you have some downloading problems, please don't hesitate to contact me at xudongzhuanyong@163.com. For Chinese users, you can download the related tools from the "Releases" of our gitee account.
Xu D, Zhang J, Zhao X, Hou Y, Jiang H, He W, Ma X, Pan W: CIDP: a multi-functional platform for designing CRISPR sgRNAs. Horticulture Research 2023, 10(7):uhad092. https://doi.org/10.1093/hr/uhad092