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fc3d374
Update README.md
brendanreardon Jan 8, 2021
714649f
Create LICENSE
brendanreardon Feb 12, 2021
d0140b3
Release 0.4.1 (#1)
brendanreardon Mar 1, 2021
153237f
Renamed FireCloud to Terra
brendanreardon Apr 29, 2021
875d72e
Update README.md
brendanreardon Sep 30, 2021
441c985
Update README.md
brendanreardon Sep 30, 2021
a0beea6
Update description-of-inputs.md
brendanreardon Sep 30, 2021
bc096d3
Update README.md
brendanreardon Nov 4, 2021
92ac79c
Added MSigDB
brendanreardon Feb 4, 2022
758a977
Added README for datasources
brendanreardon Feb 4, 2022
ed38b4f
Revised README
brendanreardon Feb 4, 2022
a2806c1
Added means to download evaluated preclinical data
brendanreardon Feb 4, 2022
fe19028
Added file sizes and md5 to preclinical download
brendanreardon Feb 4, 2022
9fbda13
Added file sizes and md5 to preclinical download
brendanreardon Feb 4, 2022
18f3cc7
Added additional hyperlinks to README
brendanreardon Feb 4, 2022
214cb73
Revised EXAC Readme
brendanreardon Feb 8, 2022
ccb3c15
Migrated documentation, scripts, and building of preclinical datasour…
brendanreardon Feb 10, 2022
19bce17
Release 0.4.2 (#3)
brendanreardon Feb 15, 2022
6ab3d7f
Tumor mutational burden display (#4)
brendanreardon Mar 4, 2022
9929710
Flexible maf import (#5)
brendanreardon Apr 13, 2022
ef7c18d
Label report and additional matches output at generation (#6)
brendanreardon Apr 26, 2022
414a496
Documentation update (#7)
brendanreardon Apr 29, 2022
f87ead4
Revised spelling of GitHub to capitalize H
brendanreardon Sep 8, 2022
206be6f
Specify output directory (#8)
brendanreardon Oct 5, 2022
2d766ff
Revise to use in memory db (#9)
brendanreardon Mar 9, 2023
5a759c6
Simplified input (#10)
brendanreardon Mar 9, 2023
eaf86ed
Update datasources (#12)
brendanreardon Mar 9, 2023
ecbac9c
Updated OncoTree citation
brendanreardon Mar 9, 2023
e125d55
Bug fix: Report generation without preclinical efficacy data (#14)
brendanreardon Apr 13, 2023
09fab94
Update Python to 3.11 (#13)
brendanreardon Apr 13, 2023
56fe007
Updated moalmanac db to v.2023-04-06
brendanreardon Apr 13, 2023
c1a27c9
Update README.md
brendanreardon Aug 8, 2023
6a328cf
Added AIP to hereditary cancers gene list (#15)
brendanreardon Oct 31, 2023
f8c4501
Update db to 2023-11-09 (#16)
brendanreardon Nov 22, 2023
37c7b04
Revise handling of COSMIC mutational signatures (#17)
brendanreardon Nov 22, 2023
40fd946
Update to Python 3.12 (#18)
brendanreardon May 13, 2024
9c6823c
Updated moalmanac db to 2024-04-11 release (#19)
brendanreardon May 15, 2024
10561af
Remove database generation from main function (#21)
brendanreardon Jul 12, 2024
20ee1e3
Adding logging (#22)
brendanreardon Oct 1, 2024
5b40001
2024-10-23 bug changes (#23)
brendanreardon Oct 25, 2024
73053f9
Update db to 2024-10-03 (#24)
brendanreardon Oct 25, 2024
3dd2e13
Update documentation hyperand docker (#25)
brendanreardon Nov 6, 2024
1911f24
Revert "Update documentation and docker" (#26)
brendanreardon Nov 6, 2024
1477682
Update documentation and docker (#27)
brendanreardon Nov 6, 2024
a4f7042
Bug fix: failing on empty read count columns (#28)
brendanreardon Nov 22, 2024
7926480
Shutdown logging (#29)
brendanreardon Nov 26, 2024
242ab69
Add two additional outputs (#30)
brendanreardon Dec 10, 2024
3cf4682
Updated moalmanac db to 2024-12-05 release (#31)
brendanreardon Dec 10, 2024
4c01f68
Resolve warnings with partial empty input files (#32)
brendanreardon Dec 24, 2024
7232160
Updated docker build to support multiple architectures (#33)
brendanreardon Jan 27, 2025
9691257
Updated hyperlinks in OncoTree documentation, noted in argument docum…
brendanreardon Jan 28, 2025
b2eedf8
Revert "Updated hyperlinks in OncoTree documentation, noted in argume…
brendanreardon Jan 30, 2025
da834b6
Revisions to datasource documentation (#35)
brendanreardon Jan 30, 2025
df30133
Update moalmanac db to 2025-02-07 release (#36)
brendanreardon Feb 7, 2025
8c44233
Resolve pylint errors
lhuhmann May 20, 2025
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60 changes: 34 additions & 26 deletions Dockerfile
Original file line number Diff line number Diff line change
@@ -1,43 +1,51 @@
FROM vanallenlab/almanac:base
FROM vanallenlab/miniconda:3.12

WORKDIR /

RUN apt-get update && apt-get install -y

COPY requirements.txt /
RUN pip install --upgrade pip
RUN pip install -r requirements.txt

COPY example_data/ /example_data/
COPY example_output/ /example_output/
COPY test/ /test/

RUN mkdir /moalmanac/
RUN mkdir /moalmanac/datasources/

COPY moalmanac/datasources/acmg/ /moalmanac/datasources/acmg/
COPY moalmanac/datasources/almanac/ /moalmanac/datasources/almanac/
COPY moalmanac/datasources/cancergenecensus/ /moalmanac/datasources/cancergenecensus/
COPY moalmanac/datasources/cancerhotspots/ /moalmanac/datasources/cancerhotspots/
COPY moalmanac/datasources/clinvar/ /moalmanac/datasources/clinvar/
COPY moalmanac/datasources/cosmic/ /moalmanac/datasources/cosmic/
COPY moalmanac/datasources/exac/ /moalmanac/datasources/exac/
COPY moalmanac/datasources/gsea_gene_sets/ /moalmanac/datasources/gsea_gene_sets/
COPY moalmanac/datasources/hereditary/ /moalmanac/datasources/hereditary/
COPY moalmanac/datasources/lawrence/ /moalmanac/datasources/lawrence/
COPY moalmanac/datasources/oncotree/ /moalmanac/datasources/oncotree/

COPY moalmanac/datasources/preclinical/almanac-gdsc-mappings.json /moalmanac/datasources/preclinical/almanac-gdsc-mappings.json
COPY moalmanac/datasources/preclinical/cell-lines.summary.txt /moalmanac/datasources/preclinical/cell-lines.summary.txt
COPY moalmanac/datasources/preclinical/ccle.variants.evaluated.txt /moalmanac/datasources/preclinical/ccle.variants.evaluated.txt
COPY moalmanac/datasources/preclinical/ccle.copy-numbers.evaluated.txt /moalmanac/datasources/preclinical/ccle.copy-numbers.evaluated.txt
COPY moalmanac/datasources/preclinical/sanger.fusions.evaluated.txt /moalmanac/datasources/preclinical/sanger.fusions.evaluated.txt
COPY moalmanac/datasources/preclinical/sanger.fusions.gene1.evaluated.txt /moalmanac/datasources/preclinical/sanger.fusions.gene1.evaluated.txt
COPY moalmanac/datasources/preclinical/sanger.fusions.gene2.evaluated.txt /moalmanac/datasources/preclinical/sanger.fusions.gene2.evaluated.txt
COPY moalmanac/datasources/preclinical/sanger.gdsc.txt /moalmanac/datasources/preclinical/sanger.gdsc.txt
COPY moalmanac/datasources/preclinical/cell-lines.pkl /moalmanac/datasources/preclinical/cell-lines.pkl
RUN mkdir /datasources
RUN mkdir /docs/

COPY moalmanac/test/ moalmanac/test/

COPY datasources/acmg/ /datasources/acmg/
COPY datasources/cancergenecensus/ /datasources/cancergenecensus/
COPY datasources/cancerhotspots/ /datasources/cancerhotspots/
COPY datasources/clinvar/ /datasources/clinvar/
COPY datasources/cosmic/ /datasources/cosmic/
COPY datasources/exac/ /datasources/exac/
COPY datasources/gsea_gene_sets/ /datasources/gsea_gene_sets/
COPY datasources/hereditary/ /datasources/hereditary/
COPY datasources/lawrence/ /datasources/lawrence/
COPY datasources/oncotree/ /datasources/oncotree/

COPY moalmanac/templates/ /moalmanac/templates/
COPY moalmanac/wrapper_deconstructsigs.sh moalmanac/run_deconstructsigs.R /moalmanac/
COPY moalmanac/*.py moalmanac/*.ini /moalmanac/

COPY datasources/moalmanac/ /datasources/moalmanac/

COPY datasources/preclinical/README.md /datasources/preclinical/README.md
COPY datasources/preclinical/generate-dictionary.ipynb /datasources/preclinical/generate-dictionary.ipynb
COPY datasources/preclinical/cell-lines.pkl /datasources/preclinical/cell-lines.pkl
COPY datasources/preclinical/formatted/almanac-gdsc-mappings.json /datasources/preclinical/formatted/almanac-gdsc-mappings.json
COPY datasources/preclinical/formatted/cell-lines.summary.txt /datasources/preclinical/formatted/cell-lines.summary.txt
COPY datasources/preclinical/annotated/cell-lines.somatic-variants.annotated.txt /datasources/preclinical/annotated/cell-lines.somatic-variants.annotated.txt
COPY datasources/preclinical/annotated/cell-lines.copy-numbers.annotated.txt /datasources/preclinical/annotated/cell-lines.copy-numbers.annotated.txt
COPY datasources/preclinical/annotated/cell-lines.fusions.annotated.txt /datasources/preclinical/annotated/cell-lines.fusions.annotated.txt
COPY datasources/preclinical/annotated/cell-lines.fusions.annotated.gene1.txt /datasources/preclinical/annotated/cell-lines.fusions.annotated.gene1.txt
COPY datasources/preclinical/annotated/cell-lines.fusions.annotated.gene2.txt /datasources/preclinical/annotated/cell-lines.fusions.annotated.gene2.txt
COPY datasources/preclinical/formatted/sanger.gdsc.txt /datasources/preclinical/formatted/sanger.gdsc.txt

COPY docs/* /docs/
COPY README.md /
COPY LICENSE /
COPY Dockerfile /
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