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TEbenchmarking

Benchmarking single-cell, locus-specific TE analysis tools in scRNA-seq

Preprocessing and TE quantification

Snakemake workflow in folders:

  • config (config file)
  • workflow (Snakefile, rules and conda environments)

Dockerfile: Dockerfile_containerize

Data simulation

Scripts for data simulation using Minnow and splatter in folder simulations

Evaluation

Notebooks with analysis used for tool evaluation available in folder evaluation

Preprint published on Biorxiv (10.64898/2026.02.26.708244)

Data is be available on Zenodo (10.5281/zenodo.18772673)

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Benchmarking computational tools for locus-specific analysis of transposable elements in single-cell RNA-seq datasets

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  • Jupyter Notebook 87.1%
  • Python 10.4%
  • Shell 1.9%
  • R 0.6%