Joint transcriptome and regulome analysis in the developing human brain cortex at the single cell level

Description

• merge_samples.R describes the process of creating a single Seurat object from Cell Ranger ARC outputs of different samples.
• preprocessing.R includes quality control, pre-processing and clustering steps on the raw data.
• pseudobulk.R shows how to create the aggregated pseudobulk samples.
• varcomp.R implements the variance component model.
• links.R includes peak-gene links identification, and DORC-related quantification.
• trajectory.R describes trajectory pseudotime analysis on neuronal populations.
• run_tradeseq.R contains downstream pseudotime analysis by using tradeSeq.